ABRAHAO FONTES BAPTISTA
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina
LIM/54 - Laboratório de Bacteriologia, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
- Author response: Insular and anterior cingulate cortex deep stimulation for central neuropathic pain: Disassembling the percept of pain(2020) ANDRADE, Daniel Ciampi de; GALHARDONI, Ricardo; SILVA, Valquiria Aparecida da; GARCIA-LARREA, Luis; DALE, Camila; BAPTISTA, Abrahao F.; BARBOSA, Luciana Mendonca; MENEZES, Luciana Mendes Bahia; SIQUEIRA, Silvia R. D. T. de; VALERIO, Fernanda; ROSI, Jefferson; RODRIGUES, Antonia Lilian de Lima; FERNANDES, Diego Toledo Reis Mendes; SELINGARDI, Priscila Mara Lorencini; MARCOLIN, Marco Antonio; DURAN, Fabio Luis de Souza; ONO, Carla Rachel; LUCATO, Leandro Tavares; FERNANDES, Ana Mercia B. L.; SILVA, Fabio E. F. da; YENG, Lin T.; BRUNONI, Andre R.; BUCHPIGUEL, Carlos A.; TEIXEIRA, Manoel J.
- Transcranial direct current stimulation relieves the severe anxiety of a patient with COVID-19(2020) SHINJO, Samuel Katsuyuki; BRUNONI, Andre Russowsky; OKANO, Alexandre Hideki; TANAKA, Clarice; BAPTISTA, Abrahao Fontes
- Applications of Non-invasive Neuromodulation for the Management of Disorders Related to COVID-19(2020) BAPTISTA, Abrahao Fontes; BALTAR, Adriana; OKANO, Alexandre Hideki; MOREIRA, Alexandre; CAMPOS, Ana Carolina Pinheiro; FERNANDES, Ana Mercia; BRUNONI, Andre Russowsky; BADRAN, Bashar W.; TANAKA, Clarice; ANDRADE, Daniel Ciampi de; MACHADO, Daniel Gomes da Silva; MORYA, Edgard; TRUJILLO, Eduardo; SWAMI, Jaiti K.; CAMPRODON, Joan A.; MONTE-SILVA, Katia; SA, Katia Nunes; NUNES, Isadora; GOULARDINS, Juliana Barbosa; BIKSON, Marom; SUDBRACK-OLIVEIRA, Pedro; CARVALHO, Priscila de; DUARTE-MOREIRA, Rafael Jardim; PAGANO, Rosana Lima; SHINJO, Samuel Katsuyuki; ZANA, YossiBackground: Novel coronavirus disease (COVID-19) morbidity is not restricted to the respiratory system, but also affects the nervous system. Non-invasive neuromodulation may be useful in the treatment of the disorders associated with COVID-19. Objective: To describe the rationale and empirical basis of the use of non-invasive neuromodulation in the management of patients with COVID-10 and related disorders. Methods: We summarize COVID-19 pathophysiology with emphasis of direct neuroinvasiveness, neuroimmune response and inflammation, autonomic balance and neurological, musculoskeletal and neuropsychiatric sequela. This supports the development of a framework for advancing applications of non-invasive neuromodulation in the management COVID-19 and related disorders. Results: Non-invasive neuromodulation may manage disorders associated with COVID-19 through four pathways: (1) Direct infection mitigation through the stimulation of regions involved in the regulation of systemic anti-inflammatory responses and/or autonomic responses and prevention of neuroinflammation and recovery of respiration; (2) Amelioration of COVID-19 symptoms of musculoskeletal pain and systemic fatigue; (3) Augmenting cognitive and physical rehabilitation following critical illness; and (4) Treating outbreak-related mental distress including neurological and psychiatric disorders exacerbated by surrounding psychosocial stressors related to COVID-19. The selection of the appropriate techniques will depend on the identified target treatment pathway. Conclusion: COVID-19 infection results in a myriad of acute and chronic symptoms, both directly associated with respiratory distress (e.g., rehabilitation) or of yet-to-be-determined etiology (e.g., fatigue). Non-invasive neuromodulation is a toolbox of techniques that based on targeted pathways and empirical evidence (largely in non-COVID-19 patients) can be investigated in the management of patients with COVID-19.
- Update on the Use of Transcranial Electrical Brain Stimulation to Manage Acute and Chronic COVID-19 Symptoms(2020) PILLONI, Giuseppina; BIKSON, Marom; BADRAN, Bashar W.; GEORGE, Mark S.; KAUTZ, Steven A.; OKANO, Alexandre Hideki; BAPTISTA, Abrahao Fontes; CHARVET, Leigh E.The coronavirus disease 19 (COVID-19) pandemic has resulted in the urgent need to develop and deploy treatment approaches that can minimize mortality and morbidity. As infection, resulting illness, and the often prolonged recovery period continue to be characterized, therapeutic roles for transcranial electrical stimulation (tES) have emerged as promising non-pharmacological interventions. tES techniques have established therapeutic potential for managing a range of conditions relevant to COVID-19 illness and recovery, and may further be relevant for the general management of increased mental health problems during this time. Furthermore, these tES techniques can be inexpensive, portable, and allow for trained self-administration. Here, we summarize the rationale for using tES techniques, specifically transcranial Direct Current Stimulation (tDCS), across the COVID-19 clinical course, and index ongoing efforts to evaluate the inclusion of tES optimal clinical care.
- Balance assessment in HTLV-1 associated myelopathy or tropical spastic paraparesis(2020) PATRICIO, Naiane Araujo; RIOS, Monica Andrade; BARBOSA, Patricia Carvalho; RIBEIRO, Jessica Ramos; VIDAL, Diogo Guedes; SA, Katia Nunes; BAPTISTA, Abrahao FontesIntroduction: A good rating of the device in people with HTLV-1 in this population is essential for accuracy in prescribing data (walking). Thus, this study aimed to analyze the counterpart assessment methods that are best suited to patients with human T-cell lymphotropic virus (HTLV)-1 associated myelopathy or tropical spastic paraparesis (HAM/TSP). Methods: This cross-sectional study related stabilometric and kinematic variables of postural oscillations with Berg's balance scale (BBS) and Timed Up and Go (TUG) in subjects with HAM/1'SP compared to asymptomatic subjects. To assess the posterior and lateral postural projection, baropodornetry and the Footwork (R) system was used, and the CVMob system was applied to kinematic parameters. The means comparison tests and correlations were applied with an alpha of 5%. Results: Thirty-nine subjects (predominantly female) made up the sample. There was an increase in barodopometric oscillations, in the total oscillation area (p = 0.004), in the anteroposterior oscillation in the left (p = 0.015) and right views (p = 0.036), and in the lateral oscillation (p = 0.039) in the HAM/TSP group. Moderate correlations were found between oscillation baropodometry and the angular variation of the ankle, as well as with the BBS in the three angles and the TUG for lateral oscillation (p = 0.406). Conclusions: Each method has advantages and disadvantages, including cost accuracy. The best resources available at no additional cost for outpatient to use are the kinematic evaluation using a simple smartphone camera and free analysis software, and the TUG.
- Does meditation lead to a stable mind? Synchronous stability and time-varying graphs in meditators(2020) TOUTAIN, Thaise G.; BAPTISTA, Abrahao F.; JAPYASSU, Hilton F.; ROSARIO, Raphael S.; PORTO, Joel A.; CAMPBELL, Fernanda Q.; V, Jose Garcia MirandaThe dynamical approach represents a new branch in the understanding of functional brain networks. Using simple indices to represent time connectivity and topological stability, we evaluated the hypothesis of increased brain stability during the meditative state in comparison to the relaxation state. We used a new way to consider the time evolution of synchronization patterns in electroencephalography (EEG) data. The time-varying graph approach and the motif synchronization method were combined to build a set of graphs representing time evolution for the synchronization of 29 EEG electrodes. We analysed these graphs during meditation and relaxation states in 17 experienced meditators. As result, we found significant increasing of time connectivity (t(15) = -2.50, p = 0.023) and topological stability (t(15) = 1.23, p = 0.020) in the meditation state when compared to the relaxation state. These findings suggest that dynamical properties of the synchronization network may revel aspects of brain activity in altered states of consciousness not possible to measure using a static approach. We concluded that the topological patterns evolution in the functional networks of experienced meditators are more stable in the meditative state than in the relaxation state.