CLEIDE GUIMARAES MACHADO CARANI

(Fonte: Lattes)
Índice h a partir de 2011
7
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina

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  • article 1 Citação(ões) na Scopus
    Large inferior retinectomies for proliferative vitreoretinopathy in silicone oil-filled eyes
    (2022) BARBOSA, Gabriel Castilho Sandoval; SILVA, Allan Gomes da; REIS, Guilherme Daher Goncalves Monteiro dos; BERMUDES, Frederico Hackbart; LEMOS, Carolina Maria Barbosa; GARCIA, Rafael; MAZZEO, Thiago Jose Muniz Machado; MACHADO, Cleide Guimaraes; GOMES, Andre Marcelo Vieira
    Background: To describe the anatomical and functional outcomes and late complications in patients who developed inferior proliferative vitreoretinopathy (PVR) in silicone oil-filled eyes and who required reoperation with large inferior retinectomy. Methods: This is a single-center, retrospective, interventional case series analysis. The study involved 18 individuals with tractional retinal re-detachment due to PVR development inferiorly in eyes who had undergone prior pars plana vitrectomy and silicone oil as a tamponade. All patients included in the study underwent secondary surgery with large inferior retinectomy (from 120 degrees to 270 degrees) and silicone oil filling. Results: The mean follow-up period was 44.0 +/- 31.5 (+/- SD) months (range: 4 to 96 months. The anatomical success, defined as the complete reattachment of the retina until the last follow-up, was observed in 88.9% of the cases. The postoperative visual acuity ranged from 20/100 to hand motion at 60 cm. Only two cases (11.1%) did not achieve anatomical success at the last follow-up due to recurrent PVR and retinal re-detachment (one including hypotony). All of the patients were pseudophakic. The PVR grade, as well as the presence of PVR prior to primary surgery, showed no statistical correlation with BCVA, the extent of retinectomies, and final macular status. There was a statistically significant correlation between ""Final BCVA"" and ""Initial BCVA"" (r = 0.654) and between ""Final BCVA"" and ""Extent of Retinectomy"" (r = 0.615). Conclusions: Reoperation in eyes filled with silicone oil may be required when PVR is developed. Secondary surgery in these cases with large inferior retinectomy and silicone oil implantation may reach good anatomical success with low rates of late complications, besides improving visual acuity. A better BCVA at the time of re-RD diagnosis and cases of retinectomies with greater extensions showed a positive correlation with better functional outcomes. Trial registration Research Ethics Committee of the Suel Abujamra Institute reviewed and approved this study protocol (approval number, 5.404.961).
  • article 1 Citação(ões) na Scopus
    Fingerprint sign in Vogt-Koyanagi-Harada disease: a case series
    (2022) MISSAKA, Ruy Felippe Brito Goncalves; GOLDBAUM, Mauro; MACHADO, Cleide Guimaraes; JR, Emmett T. Cunningham; SOUTO, Fernanda Maria Silveira; LAVEZZO, Marcelo Mendes; NOBREGA, Priscilla Figueiredo Campos da; SAKATA, Viviane Mayumi; OYAMADA, Maria Kiyoko; HIRATA, Carlos Eduardo; YAMAMOTO, Joyce Hisae
    Background The tomographic finding, which has been called the ""fingerprint sign"" in en face reconstructions, seems to be the result of a variety of processes that cause distension of the outer plexiform layer (OPL) and the Henle fiber layer (HFL). The aim of this paper is to describe the appearance of concentric rings at the OPL/HFL interface visualized using en face reconstructions of cross-sectional optical coherence tomography images of patients with Vogt-Koyanagi-Harada disease. Methods Retrospective analysis of images of six eyes of three patients obtained by cross-sectional OCT imaging and en face reconstruction at the level of the OPL/HFL interface. Results All eyes presented with a dentate or saw-tooth pattern of the OPL/HFL interface on cross-sectional OCT with corresponding concentric rings on en face OCT reconstruction, consistent with the recently published ""fingerprint sign"". Initial OPL/HFL interface changes were observed between the first and fourth months after treatment and resolution of VKHD associated serous retinal detachments. These OPL/HFL interface changes have persisted for many years following the resolution of the active inflammation. Conclusions Changes in the OPL/HFL interface can be identified following successful treatment of VKHD. These included both a dentate or saw-tooth pattern on cross-sectional imaging and concentric rings or the ""fingerprint sign"" on en face reconstructions. These changes persisted for many years despite disease quiescence.