SERGIO EDUARDO DEMARZO

Índice h a partir de 2011
4
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico

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Agora exibindo 1 - 6 de 6
  • article 4 Citação(ões) na Scopus
    Early complications in flexible bronchoscopy at a university hospital
    (2020) JACOMELLI, Marcia; MARGOTTO, Stephania Silva; DEMARZO, Sergio Eduardo; SCORDAMAGLIO, Paulo Rogerio; CARDOSO, Paulo Francisco Guerreiro; PALOMINO, Addy Lidvina Mejia; FIGUEIREDO, Viviane Rossi
    Objective: To analyze the complications related to flexible bronchoscopy (FB) and its collection procedures in outpatients and inpatients with various lung and airway diseases treated at a university hospital. Methods: This was a retrospective analysis of complications occurring during or within 2 h after FB performed between January of 2012 and December of 2013, as recorded in the database of the respiratory endoscopy department of a hospital complex in the city of Sao Paulo, Brazil. Results: We analyzed 3,473 FBs. Complications occurred in 185 procedures (5.3%): moderate to severe bleeding, in 2.2%; pneumothorax, in 0.7%; severe bronchospasm, in 0.8%; general complications (hypoxemia, psychomotor agitation, arrhythmias, vomiting, or hypotension), in 1.6%; and cardiopulmonary arrest, in 0.03%. There were no deaths related to the procedures. Specifically, among the 1,728 patients undergoing biopsy, bronchial brushing, or fine-needle aspiration biopsy, bleeding occurred in 75 (4.3%). Among the 1,191 patients undergoing transbronchial biopsy, severe pneumothorax (requiring chest tube drainage) occurred in 24 (2.0%). Conclusions: In our patient sample, FB proved to be a safe method with a low rate of complications. Appropriate continuing training of specialist doctors and nursing staff, as well as the development of standardized care protocols, are important for maintaining those standards.
  • article 0 Citação(ões) na Scopus
    Bronchoscopy in COVID-19 inpatients: experience of a university hospital in the first outbreak of the disease in Brazil
    (2022) DEMARZO, Sergio Eduardo; MELO, Julia Bamberg Cunha; CARRANZA, Mariasol Ximena Martinez; OLIVEIRA, Felipe Nominando Diniz; FERREIRA, Anaregia de Pontes; PALOMINO, Addy Lidvina Mejia; FIGUEIREDO, Viviane Rossi; JACOMELLI, Marcia
    Objective: To describe the indications and endoscopic findings of bronchoscopy performed at a reference university hospital for inpatients diagnosed with COVID-19 during the first outbreak of the disease in Brazil. Methods: A retrospective analysis of medical records of adult patients diagnosed with COVID-19 who underwent bronchoscopy at the intensive care units of Instituto do Coracao and Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, from March to August 2020. Results: A total of 132 bronchoscopies were performed in 103 patients diagnosed with COVID-19. Mean age was 56.1 +/- 14.5 years, and distribution was similar in both sexes. More than one test was performed in 16 patients. The most frequent indications were diagnostic endoscopic evaluation and therapeutic procedures in 78.6% of cases (n=81) and material collection in 21.4% of cases (n=22). The most frequent endoscopic findings were presence of secretion or clots in 34% of cases, the presence of acute inflammatory changes in 22.3%, and tracheal wall laceration in 20.4%. In 27.2% of patients, no relevant bronchoscopic findings were observed. In three patients, bronchoscopy was indicated to assess hemoptysis, but there was only one case of active bleeding. Procedure-related complications were not observed in this group of patients. Conclusion: Bronchoscopy proved to be a safe and effective procedure to assist in treatment of COVID-19 patients, and the most frequent indications were related to investigation of airway involvement or to evaluate infectious and inflammatory pulmonary processes.
  • article 2 Citação(ões) na Scopus
    Radial echo-bronchoscopy for the diagnosis of peripheral lung lesions Response
    (2017) JACOMELLI, Marcia; DEMARZO, Sergio Eduardo; CARDOSO, Paulo Francisco Guerreiro; PALOMINO, Addy Lidvina Mejia; FIGUEIREDO, Viviane Rossi
  • article 10 Citação(ões) na Scopus
    Endobronchial ultrasound-guided transbronchial needle aspiration for lung cancer staging: early experience in Brazil
    (2015) FIGUEIREDO, Viviane Rossi; CARDOSO, Paulo Francisco Guerreiro; JACOMELLI, Marcia; DEMARZO, Sergio Eduardo; PALOMINO, Addy Lidvina Mejia; RODRIGUES, Ascedio Jose; TERRA, Ricardo Mingarini; PEGO-FERNANDES, Paulo Manoel; CARVALHO, Carlos Roberto Ribeiro
    Objective: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive, safe and accurate method for collecting samples from mediastinal and hilar lymph nodes. This study focused on the initial results obtained with EBUS-TBNA for lung cancer and lymph node staging at three teaching hospitals in Brazil. Methods: This was a retrospective analysis of patients diagnosed with lung cancer and submitted to EBUS-TBNA for mediastinal lymph node staging. The EBUS-TBNA procedures, which involved the use of an EBUS scope, an ultrasound processor, and a compatible, disposable 22 G needle, were performed while the patients were under general anesthesia. Results: Between January of 2011 and January of 2014, 149 patients underwent EBUS-TBNA for lymph node staging. The mean age was 66 +/- 12 years, and 58% were male. A total of 407 lymph nodes were sampled by EBUS-TBNA. The most common types of lung neoplasm were adenocarcinoma (in 670%) and squamous cell carcinoma (in 24%). For lung cancer staging, EBUS-TBNA was found to have a sensitivity of 96%, a specificity of 100%, and a negative predictive value of 85%. Conclusions: We found EBUS-TBNA to be a safe and accurate method for lymph node staging in lung cancer patients.
  • article 3 Citação(ões) na Scopus
    The role of endobronchial ultrasoundguided transbronchial needle aspiration in isolated intrathoracic lymphadenopathy in non-neoplastic patients: a common dilemma in clinical practice
    (2020) SANTOS, Lilia Maia; FIGUEIREDO, Viviane Rossi; DEMARZO, Sergio Eduardo; PALOMINO, Addy Lidvina Mejia; JACOMELLI, Marcia
  • article 11 Citação(ões) na Scopus
    Ecobroncoscopia radial para o diagnóstico de lesões pulmonares periféricas
    (2016) JACOMELLI, Marcia; DEMARZO, Sergio Eduardo; CARDOSO, Paulo Francisco Guerreiro; PALOMINO, Addy Lidvina Mejia; FIGUEIREDO, Viviane Rossi
    Objetivo: A broncoscopia convencional possui baixo rendimento diagnóstico para lesões pulmonares periféricas. A ecobroncoscopia radial (EBUS radial) emprega um transdutor ultrassonográfico rotatório na extremidade de uma sonda que é inserida no canal de trabalho do broncoscópio. O EBUS radial facilita a localização de nódulos pulmonares periféricos, aumentando assim o rendimento diagnóstico. O objetivo deste estudo foi apresentar nossa experiência inicial com o uso de EBUS radial para o diagnóstico de lesões pulmonares periféricas em um hospital terciário. Métodos: Foi realizada uma análise retrospectiva de 54 pacientes submetidos à broncoscopia guiada por EBUS radial para a investigação de nódulos ou massas pulmonares entre fevereiro de 2012 e setembro de 2013. O EBUS radial foi realizado com uma sonda flexível de 20 MHz, que foi inserida no canal de trabalho do broncoscópio até chegar à lesão-alvo. A fluoroscopia foi usada para localizar a lesão e realizar procedimentos de coleta (escovado brônquico, aspiração transbrônquica com agulha e biópsia transbrônquica). Resultados: O EBUS radial identificou 39 nódulos (média de diâmetro: 1,9 ± 0,7 cm) e 19 massas (média de diâmetro: 4,1 ± 0,9 cm). A sensibilidade global do EBUS radial foi de 66,7% (79,5% para as lesões visíveis pelo método e 25% para as lesões não visíveis pelo método). Nas lesões visíveis pelo método, a sensibilidade foi de 91,7% para massas e de 74,1% para nódulos. As complicações foram pneumotórax (3,7%) e sangramento brônquico controlado broncoscopicamente (9,3%). Conclusões: O EBUS radial apresenta bom perfil de segurança, baixo índice de complicações e alta sensibilidade para o diagnóstico de lesões pulmonares periféricas.