IBERE CAUDURO SOARES
Índice h a partir de 2011
10
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/14 - Laboratório de Investigação em Patologia Hepática, Hospital das Clínicas, Faculdade de Medicina
LIM/24 - Laboratório de Oncologia Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/14 - Laboratório de Investigação em Patologia Hepática, Hospital das Clínicas, Faculdade de Medicina
LIM/24 - Laboratório de Oncologia Experimental, Hospital das Clínicas, Faculdade de Medicina
12 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 12
conferenceObject Congenital Hypopituitarism: Stem Cell Accumulation in Mutants with Developmental Arrest and Depletion in Mutants with Hyperplasia(2014) CHANG, Claudia Veiga; ARAUJO, Ricardo Viera; CIRQUEIRA, Cinthya Santos; PARFIENIUK, Agata; GUZZO, Mariana F.; BENEDETTI, Anna Flavia F.; SOARES, Ibere C.; MILLAN, Maria Ines Perez; CAMPER, Sally Ann; CARVALHO, Luciani R. S.conferenceObject A Lower Ki 67 Labelling Index (LI) Cut-Point Improves the Prognostic Assessment and Might Aid in the Diagnosis of Adult Adrenocortical Tumors(2018) MARTINS FILHO, Sebastiao N.; ALMEIDA, Madson Q.; SOARES, Ibere C.; WAKAMATSU, Alda; ALVES, Venancio; FRAGOSO, Maria C.; ZERBINI, MariaconferenceObject ESOPHAGOGASTRIC JUNCTION ADENOCARCINOMA MAY BE BIOLOGICALLY CLASSIFIED BY IMMUNOEXPRESSION OF MOLECULAR MARKERS(2023) MARQUES, Sergio B.; SOARES, Ibere C.; RIBEIRO, Mateus B.; PEREIRA, Marina A.; TAKEDA, Flavio R.; SZACHNOWICZ, Sergio; SALLUM, Rubens A.; MALUF-FILHO, Fauze; RIBEIRO, Ulysses; SAFATLE-RIBEIRO, Adriana V.conferenceObject A Lower Ki 67 Labelling Index (LI) Cut-Point Improves the Prognostic Assessment and Might Aid in the Diagnosis of Adult Adrenocortical Tumors(2018) MARTINS FILHO, Sebastiao N.; ALMEIDA, Madson Q.; SOARES, Ibere C.; WAKAMATSU, Alda; ALVES, Venancio; FRAGOSO, Maria C.; ZERBINI, MariaconferenceObject EGFR GENOTYPING AND EPIDEMIOLOGY, CLINICAL AND PATHOLOGICAL FEATURES IN 191 PATIENTS WITH METASTATIC PULMONARY ADENOCARCINOMA IN SAO PAULO - BRAZIL.(2013) CASTRO JR., Gilberto; TAKAHASHI, Tiago K.; CAIRES-LIMA, Rafael; PROTASIO, Bruno M.; MAIA, Manuel C. D. F.; SOARES, Ibere C.; ROITBERG, Felipe S. R.; MARINI, Andrea M.; MARTINS, Renata E.; TAKAGAKI, Teresa Y.; ARAUJO, Pedro H. X. N.; TERRA, Ricardo M.; SHIANG, Christina; SIQUEIRA, Sheila A. C.; MELLO, Evandro S.; ALVES, Venancio A.; HOFF, Paulo M.conferenceObject An uncommon beta catenin gene deletion in a breast desmoid-type fibromatosis(2017) SOARES, I. Cauduro; VASCONCELOS, M. A. Pereira Silva; LIMA, L. G. Cernaglia Aureliano de; BATISTA, R. Pedroso; AGUIAR, F. Nalesso; SHIMIZU, C.; RICCI, M. Desiderio; FILASSI, J. R.conferenceObject Retrospective Analysis of Prognostic Factors in Pediatric Patients with Adrenocortical Tumor from Unique Tertiary Center with Long-Term Follow-up(2023) BACHEGA, Fernanda; SUARTZ, Caio; ALMEIDA, Madson; BRONDANI, Vania; CHARCHAR, Helaine; LACOMBE, Amanda; MARTINS-FILHO, Sebastiao; SOARES, Ibere; ZERBINI, Maria Claudia; DENES, Francisco; MENDONCA, Berenice; LOPES, Roberto; LATRONICO, Ana Claudia; FRAGOSO, Maria CandidaconferenceObject EGFR ACTIVATING MUTATIONS IN NSCLC: IMPORTANCE OF ROUTINE TESTING(2012) TAKAHASHI, Tiago K.; SOARES, Ibere C.; MARINI, Andrea M.; MAK, Milena P.; TEIXEIRA, Carlos H.; ROITBERG, Felipe S. R.; TAKAGAKI, Teresa Y.; MARTINS, Renata E.; MESQUITA, Cristiane; HOFF, Paulo M. G.; CASTRO JR., GilbertoBackground: EGFR activating mutations in NSCLC confer better prognosis and are also predictive of response to both chemotherapy and EGFR-tyrosine kinase inhibitors. Therefore, EGFR genotyping in NSCLC patients (pts) is very helpful in treatment decision. Here we report the first 25 pts whose tumors samples were tested for EGFR activating mutations in our Institution. Methods: It is an observational study on all consecutively tested NSCLC samples from pts treated at ICESP. Briefly, all samples were formalin-fixed and paraffin-embedded. Tumor areas were selected and macrodissected, followed by whole DNA extraction and amplification by PCR. DNA sequencing (exons 18, 19, 20 and 21) was performed by Sanger´s methodology. Frequencies were compared by Fisher´s exact test. Results and Conclusion: Results: 25 tumor samples were tested from Aug/2011 up to now: 20 pts were caucasian, 13 were male, 14 ex-smoker, 10 never smoker; 15 pts ECOG-PS 0-1 and 5 PS 2. Regarding histologic subtype, 22 were classified as adenocarcinoma and 2 SCC. Staging: 3 IIIA, 2 IIIB and 20 IV. Activating mutations were detected in 6 pts (24%): 4 in exon 19 (del 19), 1 in exon 21 (L858R) and in 1 pt two mutations were found (T790M and L858R). The frequency of these activating mutations was not related to gender (p=0.378), race (p=0.540) or smoking habits (p=0.350). In a short follow-up of 6 mo., no deaths occurred in pts whose samples were positive for activating mutations. Conclusions: In this very selected population, the frequency of EGFR activating mutations was 24%, with no correlation with gender, race or smoking habits. This reinforces the importance of testing EGFR activating mutations in all pts with lung adenocarcinoma. Disclosure: No significant relationships.conferenceObject ERLOTINIB IN METASTATIC PULMONARY ADENOCARCINOMAS HARBOURING EGFR ACTIVATING MUTATIONS, IN SAO PAULO - BRAZIL(2013) CAIRES-LIMA, Rafael; PROTASIO, Bruno M.; TAKAHASHI, Tiago K.; MAK, Milena P.; NAKAZATO, Denyei; MESQUITA, Cristiane S.; TAKAGAKI, Teresa Y.; SOARES, Ibere C.; MELLO, Evandro S.; ALVES, Venancio A.; HOFF, Paulo M.; CASTRO JR., GilbertoconferenceObject EPSTEIN-BARR TUMOR-ASSOCIATED INFECTION IS RESTRICTED TO MORE DISTAL ADENOCARCINOMA OF ESOPHAGOGASTRIC JUNCTION (AEGJ), WHILE PD-L1 IS HIGHLY IMMUNOEXPRESSED IN BOTH, ESOPHAGEAL SQUAMOUS CELL CARCINOMA (ESCC) AND AEGJ(2021) RIBEIRO, Mateus B.; MARQUES, Sergio B.; SOARES, Ibere C.; PEREIRA, Marina A.; TAKEDA, Flavio R.; MALUF-FILHO, Fauze; SALLUM, Rubens A.; ZILBERSTEIN, Bruno; SAFATLE-RIBEIRO, Adriana V.; RIBEIRO, Ulysses