MARIA ALICE PIMENTEL FALCAO
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- Characterization of consumption and costs of antimicrobials in intensive care units in a Brazilian tertiary hospital(2023) CASTRO, Tazia Lopes de; CAMBIAIS, Amanda Magalhaes Vilas Boas; SFORSIN, Andrea Cassia Pereira; PINTO, Vanusa Barbosa; FALCAO, Maria Alice PimentelBackground: The consumption of antimicrobials and the growing resistance of infectious agents to these drugs are not related only to health issues, but also to economic parameters.Objectives: The study objective was to evaluate the consumption of antimicrobials in General and Covid-19 Intensive Care Units (ICUs) and the impact on institutional costs in the largest institute of a tertiary public hospital.Methods: This is a quantitative and retrospective study, which analyzed consumption, through the Defined Daily Dose (DDD), and the annual direct cost of antimicrobials in Reais (R$) and Dollars (US$), from January to December 2021. Results: The total annual consumption (DDD/1000 patient-day) of antimicrobials in the ICUs was 14,368.85. beta-Lactams had the highest total annual value, with a DDD/1000 patient-day of 7062.98, being meropenem the antimi-crobial that reached the highest consumption (3107.20), followed by vancomycin (2322.6). Total consumption was higher in Covid-19 ICUs than in General ICUs, and the annual direct cost of antimicrobials in ICUs was US$560,680.79.Conclusions: The study showed high consumption of broad-spectrum antimicrobials, highlighting the importance of structuring programs to manage the use of antimicrobials, both to reduce antimicrobial consumption and hospital costs, consolidating rational use even in pandemic scenarios.