PAULO MANUEL PEGO FERNANDES
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cardio-Pneumologia, Faculdade de Medicina - Docente
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina - Líder
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina - Líder
50 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 50
- Great expectations(2012) PEGO-FERNANDES, Paulo Manuel; BIBAS, Benoit Jacques
- The 500th Lung Transplantation at the Faculdade de Medicina da Universidade de Sao Paulo: Reflecting on Our Journey and Looking Ahead(2023) REIS, Flavio Pola dos; PEGO-FERNANDES, Paulo Manuel
- Smartphones and health promotion(2014) MARIANI, Alessandro Wasum; PEGO-FERNANDES, Paulo Manuel
- Robotic surgery training(2023) ARAUJO, Pedro Henrique Xavier Nabuco de; PEGO-FERNANDES, Paulo Manuel
- Global Health Governance: a rising challenge(2013) MARIANI, Alessandro Wasum; PEGO-FERNANDES, Paulo Manuel
article 0 Citação(ões) na Scopus Healthcare systems: what do we want?(2011) PEGO-FERNANDES, Paulo Manuel; BIBAS, Benoit Jacquesarticle 1 Citação(ões) na Scopus Surgical treatment of heart failure: a hot topic(2011) PEGO-FERNANDES, Paulo Manuel; MONTEIRO, Rosangela- Pulmonary emphysema induced by methylphenidate: experimental study(2015) RAPELLO, Gabriel Victor Guimaraes; ANTONIOLLI, Andreia; PEREIRA, Daniel Martins; FACCO, Gilberto; PEGO-FERNANDES, Paulo Manuel; PAZETTI, RogerioCONTEXT AND OBJECTIVE: Methylphenidate is the most widely used drug for treating attention deficit hyperactivity disorder. However, it has important side effects, such as abdominal pain, insomnia, anorexia and loss of appetite, and also some cases of early severe emphysema after drug abuse have been reported. Our aim was to investigate the development of pulmonary emphysema in rats that were subjected to different doses of methylphenidate. DESIGN AND SETTING: Experimental study carried out at the laboratory of a public university. METHODS: Eighteen male Wistar rats were divided into three groups: control (0.9% saline solution); MP 0.8 (methylphenidate, 0.8 mg/kg); MP 1.2 (methylphenidate, 1.2 mg/kg). After 90 days of daily gavage, the animals were sacrificed and lung tissue samples were prepared for analysis on the mean alveolar diameter (Lm). RESULTS: The Lm was greater in MP 0.8 (47.91 +/- 3.13; P < 0.01) and MP 1.2 (46.36 +/- 4.39; P < 0.05) than in the control group (40.00 +/- 3.48). CONCLUSION: Methylphenidate caused an increase in the alveolar diameter of rats, which was compatible with human pulmonary emphysema.
- E-Learning: from useful to indispensable tool(2012) MARIANI, Alessandro Wasum; TERRA, Ricardo Mingarini; PEGO-FERNANDES, Paulo Manuel
- Three-dimensional computed tomography reconstruction in the era of digital personalized medicine(2023) ROCHA-JUNIOR, Eserval; PEGO-FERNANDES, Paulo Manuel