THAIS DELLA MANNA
Projetos de Pesquisa
Unidades Organizacionais
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina
17 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 17
conferenceObject Mixed Gonadal Disgenesia: Patients of Instituto da Crianca, HC-FMUSP(2016) FERREIRA, Marianna; PINHEIRO, Claudia; QUEIROZ, Edjane; BRIGATTI, Nathalia; ITO, Simone; STEINMETZ, Leandra; COMINATO, Louise; SETIAN, Nuvarte; DICHTCHEKENIAN, Vae; MENEZES FILHO, Hamilton; MANNA, Thais Della; DAMIANI, DurvalconferenceObject Challenged Diagnosis on Hypoglycemia: Hirata Disease X Factitious Hypoglycemia(2015) JERONIMO, T.; PASSONE, C. Buff; FARIA JUNIOR, J.; SAVOLDELLI, R. Diaz; KUPERMAN, H.; MENEZES FILHO, H. Cabral de; STEINMETZ, L.; DITCHTCHEKENIAN, V; MANNA, T. Della; DAMIANI, D.conferenceObject Central Precocious Puberty After Surgical Resection of Giant Craniopharyngioma in a Girl(2018) BEZERRA, Marilia; KLINK, Gabriela; BORNEA, Rondi; PASCHOAL, Fernanda; PASSONE, Caroline; STEINMETZ, Leandra; COMINATO, Louise; ROCHA, Ruth; MANNA, Thais; FILHO, Hamilton; DAMIANI, Durval- Translation and validation of Pediatric Quality of Life Inventory (TM) 3.0 Diabetes Module (PedsQL (TM) 3.0 Diabetes Module) in Brazil-Portuguese language(2018) GARCIA, Leila F. dos S.; MANNA, Thais Della; PASSONE, Caroline de Gouveia Buff; OLIVEIRA, Lygia Spassapan deObjective: The aim of the present study was to create a translated version of the Pediatric Quality of Life Inventory (TM) 3.0 Diabetes Module (PedsQL (TM) 3.0 Diabetes Module) in Brazilian Portuguese that was conceptually equivalent to the original American English version and to linguistically validate it in a Brazilian pediatric population with type 1 diabetes mellitus and their parents or caregivers. Methods: The instrument was translated, back-translated, and then administered to 83 children/adolescents (5-18 years) with type 1 diabetes mellitus and their family members and to 25 parents/caregivers of patients aged between 2 and 4 years. The final translated version was tested for reliability by analyzing internal consistency, intraobserver (test-retest) reliability, and concurrent validity. Results: Cronbach's alpha coefficient for the total score of the questionnaires of children/adolescents (alpha = 0.85) and their parents (alpha = 0.82) was above the recommended minimum of 0.70 for group comparisons. Intraobserver reliability and concurrent validity exhibited a significant positive correlation (p < 0.001), indicating the reliability of the translated instrument. A moderate but significant positive correlation (r = 0.40; p < 0.001) was demonstrated between the total scores of patient self-report and parent proxy-report scales. There was no significant correlation between glycated hemoglobin (HbA1c) levels and the respective scores in the questionnaires answered by patients and their parents/caregivers. Conclusion: The analysis of the translated version of the PedsQL (TM) 3.0 Diabetes Module revealed adequate psychometric characteristics with respect to reliability and validity following administration to a sample of Brazilian children/adolescents with type 1 diabetes mellitus and their caregivers. (C) 2018 Sociedade Brasileira de Pediatria.
conferenceObject Changes on Gut Microbiota after Laparoscopic Sleeve Gastrectomy in Adolescence: Case Reports(2019) RACHID, L.; COMINATO, L.; FRANCO, R. R.; V, R. Cortez; MOREIRA, L. N.; FRASCINO, A.; TADDEI, C. R.; STEINMETZ, L.; MANNA, T. Della; VELHOTE, M. C. P.; FILHO, H. C. M.; TOMA, R. K.; DAMIANI, D.conferenceObject Recurrent Orchitis in a Patient with True Hermaphroditism(2016) TEIXEIRA, T. Lyrio; SOUZA, L. Guimaraes de; MARTIN, S. San; JUSTINIANO, W.; PINHEIRO, C.; STEINMETZ, L.; COMINATO, L.; FRANCO, R. Rocha; MENEZES FILHO, H. de Cabral; MANNA, T. Della; ASSIS, L. H.; DAMIANI, D.conferenceObject Osteogenesis Imperfecta Type I: Which Patients Should Be Treated with Aminobisphosphonates?(2019) SANTOS, I. N.; MENEZES FILHO, H. C.; FRANCO, R. R.; COMINATO, L.; STEINMETZ, L.; MANNA, T. D.; DAMIANI, D.- Pitfalls in the diagnosis of insulin autoimmune syndrome (Hirata's disease) in a hypoglycemic child: a case report and review of the literature(2019) SANTOS, Tiago Jeronimo Dos; PASSONE, Caroline Gouvea Buff; YBARRA, Marina; ITO, Simone Sakura; TELES, Milena Gurgel; MANNA, Thais Della; DAMIANI, DurvalBackground: Insulin autoimmune syndrome (IAS) is a rare cause of hyperinsulinemic hypoglycemia (HH) not addressed as a potential differential diagnosis in current pediatric guidelines. We present a case of IAS in a child with no previous history of autoimmune disease, no previous intake of triggering medications and absence of genetic predisposition. Case presentation: A 6-year-old boy presented with recurrent HH (blood glucose of 26 mg/dL [1.4 mmol/L] and insulin of 686 mu U/mL). Abdominal imaging was normal. After multiple therapeutic failures, we hypothesized misuse of exogenous insulin and factitious hypoglycemia. Council of Guardianship had the child separated from his mother, but insulin levels remained high. A chromatography test was then performed which showed high titers of endogenous insulin autoantibody (IAA) with early dissociation from the insulin molecule. The human leukocyte antigen (HLA) test showed a DRB1 *13:01/*08:02 genotype. The patient was advised to control food intake and physical activity routines. During a 5-year follow-up, hypoglycemic episodes were sparse, despite high insulin levels. Conclusions: Misdiagnosis of IAS with factitious hypoglycemia may happen if IAS is not considered as a differential diagnosis, leading to potential traumatic consequences. Further efforts should be made to increase awareness of IAS as a differential diagnosis of hypoglycemia and to include it in pediatric guidelines.
conferenceObject Puberty in Patients with Ovotesticular DSD: Evaluation of 20 Patients(2019) MELARDI, J. W.; CUNHA, D. F. S.; CESPEDES, W. C. J.; CARVALHO, F. M.; COMINATO, L.; MENEZES FILHO, H. C.; MANNA, T. D.; FRANCO, R. R.; SEMER, B.; STEINMETZ, L.; DAMIANI, D.- A Dominant ABCC8-Related Hyperinsulinism: Familial Case Report Moreira et al. ABCC8-Related Hyperinsulinism(2013) MOREIRA, M. C.; PIAZZON, F. B.; CARVALHO, M. D. F.; QUAIO, C. R. D. C.; DUTRA, A. B.; CECCON, M. E.; DELLA-MANNA, T.; TANNURI, U.; LEE, J. H.; ZERBINI, M. C. N.; BELLANNE-CHANTELOT, C.; LONLAY, P.; BERTOLA, D. R.; KIM, C. A.