ROLF GEMPERLI

(Fonte: Lattes)
Índice h a partir de 2011
19
Lattes
ResearcherID
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cirurgia, Faculdade de Medicina - Docente
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/04 - Laboratório de Microcirurgia, Hospital das Clínicas, Faculdade de Medicina - Líder

Filtros

Limpar filtros

Configurações

Autor e Coautores FMUSP-HC Normalizados: MARCUS CASTRO FERREIRA ×

Resultados de Busca

Agora exibindo 1 - 10 de 28
  • article 39 Citação(ões) na Scopus
    Outcome Analysis of Immediate and Delayed Conservative Breast Surgery Reconstruction With Mastopexy and Reduction Mammaplasty Techniques
    (2011) MUNHOZ, Alexandre Mendonca; ALDRIGHI, Claudia Maria; MONTAG, Eduardo; ARRUDA, Eduardo; BRASIL, Jose Augusto; FILASSI, Jose Roberto; ALDRIGHI, Jose Mendes; GEMPERLI, Rolf; FERREIRA, Marcus Castro
    Background: Bilateral mammaplasty or mastopexy is frequently used for oncoplastic objectives. However, little information has been available regarding outcome following immediate and delayed reconstruction. Method: Patients were divided into Group I (immediate reconstruction) and Group II (delayed reconstruction). Retrospective review was performed to compare complications, length of hospital stay, revision surgeries, and satisfaction. The associations between the complications with potential risk factors (timing, age, body mass index, smoking, and comorbid medical conditions) were analyzed. Results: There were a total of 144 patients with a mean follow-up of 47 months. Of the 106 patients in Group I, complications occurred in 24 (22.6%), skin necrosis was observed in 7.5%, fat necrosis in 5.6%, and 6.6% patients developed local recurrence. Mean period of hospitalization was 1.89 days. Of the 38 patients of the Group II, complications occurred in 12 (31.5%), skin necrosis was observed in 7 (18.4%), fat necrosis in 4 (10.5%), and 5.2% patients developed local recurrence. Mean period of hospitalization was 1.35 days. Increased length of hospital stay greater than 1 day (P < 0.001) and the number of revision surgeries (P = 0.043) were associated with the timing of the reconstruction. In univariate analysis, no difference between groups was found with respect to complication incidence (P = 0.275); however, after adjusting for other risk factors, the probability of complications tend to be higher for Group II (OR = 2.65; 95% confidence interval - 1.01-7.00; P = 0.049). Conclusions: On the basis of the results of our study, the probability of complications tends to be higher for delayed reconstructions, and it is demonstrated that obesity and smoking are risk factors for complications. Ultimately, these data may facilitate the provision of individualized risk information for shared medical decision-making.
  • article 7 Citação(ões) na Scopus
    Evaluation of nerve regeneration in diabetic rats
    (2013) SALLES JR., Guatacara Schenfelder; FARIA, Jose Carlos Marques de; BUSNARDO, Fabio Freitas; GEMPERLI, Rolf; FERREIRA, Marcus Castro
    PURPOSE: To compare sciatic nerve regeneration between non-diabetic (control) and streptozotocin-induced diabetic Wistar rats. METHODS: Four subgroups were evaluated. CN: Non-diabetic rats submitted to neurorrhaphy (n=9); DN: Diabetic rats submitted to neurorrhaphy (n=9); CG: Non-diabetic rats submitted to nerve grafting (n=10); DG: Diabetic rats submitted to nerve grafting (n=9). The nerve regeneration was evaluated by walking track analysis (sciatic functional index), electrophysiological test, histomorphometric analysis and triceps surae muscle weight. RESULTS: At 60 days post-surgery, functional recovery of DN was similar to that of the non-diabetic rats (CN, CG), but DG didn't achieve the same. Evoked potential amplitudes showed no statistically significant differences among subgroups. Triceps surae muscle was heavier in CN. No statistically significant differences were observed between the control and diabetes subgroups with respect to histomorphometric analysis. CONCLUSION: After 60 days, DN had a functionally similar recovery to that of the control animals, whereas nerve grafting in diabetic rats didn't allow the same. The muscle atrophy was lower in CN. In the rest of evaluations, as electrophysiological and histomorphometric, diabetic rats were not different from control ones.
  • article 13 Citação(ões) na Scopus
    An outcome analysis and long-term viability of cryopreserved cultured epidermal allografts. Assessment of the conservation of transplantable human skin allografts
    (2013) SCHIOZER, Wandir Antonio; GEMPERLI, Rolf; MUEHLBAUER, Wolfgang; MUNHOZ, Alexandre Mendonca; FERREIRA, Marcus Castro
    PURPOSE: To assess the viability of cultured epithelium and preserved by freezing for periods varying from one month to one year. METHODS: Samples of cultured epithelium were incubated in cryoprotectant medium (Group A), packed in aluminum envelopes and packed in polystyrene boxes. The boxes were subjected to a temperature of-70 degrees C. After freezing for a period of time ranging from one to 12 months, cultured epithelial samples were assessed for their viability by vital staining (Trypan blue) and metabolic analysis based on glucose consumption and lactate production. Samples of not frozen cultured epithelium (Group B) were also tested for viability and the results obtained were used as comparison parameter for the variation of viability. RESULTS: Statistical analysis between the group A and B indicate that the mean age of the donors (p=0.51) and the culture time (p=1.18) showed no statistical difference. In 30 days we obtained 37% of the original viability of cultured epithelium, 25% at six months and one year, less than 15%. This trend was confirmed statistically with a reduction of approximately 1.8% of the original viability epithelium cultured every 30 days of storage. In the analysis by lactate production, similar results were observed. In the analysis by the glucose consumption results were not significant. The viability indices show statistically significant difference between the group A and B (p<0.0001). CONCLUSIONS: Although cryopreserved cultured epithelium showed significant reduction of viability, all samples remained viable. It was also found that the viability of cryopreserved cultured epithelial decreased as a function of storage time.
  • article
    Cirurgias plásticas para readequação de contorno corporal de pacientes submetidos a cirurgia bariátrica durante a adolescência
    (2012) ROCHA, Rodrigo Itocazo; GEMPERLI, Rolf; MODOLIN, Miguel Luiz Antonio; CINTRA JUNIOR, Wilson; VELHOTE, Manoel Carlos Prieto; FERREIRA, Marcus Castro
    BACKGROUND: Surgical treatments for obesity in adolescents were introduced in the 1990s, resulting in individuals undergoing bariatric surgery, and exhibiting weight loss and dysmorphic body features. This produced a demand for plastic surgery in order to readjust the body contour. The aim of this study was to identify factors associated with morbidity and mortality for these corrective body contouring plastic surgeries in patients who underwent bariatric surgery during adolescence. METHODS: Between January 2008 and January 2011, 5 adolescent patients underwent gastric bypass surgery, with a consequent loss and stabilization of weight, and then underwent plastic surgery for correcting body contours. The average age of the patients at the time of plastic surgery was 19.7 years; 3 (60%) patients were female. Abdominoplasty was performed in all patients (100%), crural dermolipectomy in 4 (80%) patients, brachial dermolipectomy in 2 (40%) patients, thoracoplasty in 2 (40%) patients, torsoplasty in 2 (40%) patients, and a reverse abdominoplasty in 1 (20%) patient. In addition, mammoplasty with inclusion of silicone implants was performed in 2 (40%) female patients, whereas the other female patient (20%) underwent mastopexy. A male patient (20%) underwent correction of gynecomastia. An average of 3 surgical interventions were performed on each patient (range, 2 - 5), and the number of surgical sites was 20. RESULTS: Dehiscence occurred in 3 (15% of the surgical sites) cases, and it was necessary to revise the resection because of residual skin laxity in 3 (15% of the surgical sites) patients. CONCLUSIONS: Some factors associated with body contouring plastic surgeries in adolescents were identified and compared with the literature data.
  • article 19 Citação(ões) na Scopus
    Superficial inferior epigastric artery (SIEA) free flap using perforator vessels as a recipient site: clinical implications in autologous breast reconstruction
    (2011) MUNHOZ, Alexandre Mendonca; PELLARIN, Leandro; MONTAG, Eduardo; FILASSI, Jose Roberto; TACHIBANA, Adriano; GEBRIM, Heloisa; GEMPERLI, Rolf; FERREIRA, Marcus Castro
    BACKGROUND: Breast reconstruction with autogenous tissue is a well-established technique, but there are some limitations related to donor-site morbidity. Among available techniques, the superficial inferior epigastric artery (SIEA) flap is the least invasive procedure because it does not require harvesting or incision of the rectus muscle or the abdominal fascia. Besides adequate flap choice, the proper selection of the recipient vessels is an important factor. Thus, the internal mammary perforator branches (IMPBs) have been an attractive option regarding recipient pedicle morbidity. METHODS: The investigators reported the use of the free SIEA flap with the IMPBs as a recipient site to reconstruct radical mastectomy. RESULTS: Five patients with invasive ductal carcinoma underwent modified radical mastectomy and reconstruction. The IMPBs were selected as the recipient site and a free SIEA flap was used. The donor defect was closed directly without synthetic mesh. Satisfactory breast shape was achieved, and no complications were observed. CONCLUSIONS: For selected patients, the SIEA flap and IMPBs may constitute a new alternative for immediate breast reconstruction, because of the possibility of large tissue transfer with minimal donor and recipient area morbidity. The SIEA pedicle size and the quality of IMPB vessels should be carefully evaluated.
  • article 2 Citação(ões) na Scopus
    Comparison of neurosensory devices in detecting cutaneous thresholds related to protective sensibility: A cross-sectional study in Sao Paulo, Brazil
    (2019) CARVALHO, V. F.; UEDA, T.; PAGGIARO, A. O.; NASCIMENTO, A. R. F.; FERREIRA, M. C.; GEMPERLI, R.
    Aims: To quantify the static and moving cutaneous sensibility threshold of diabetic patients using a neurosensory device for quantitative pressure detection. Methods: Three hundred thirty-four (n = 334) patients with type 2 diabetes and no previous history of wounds on the feet were studied using the one- and two-point static (1SP;2 SP) and one- and two-point moving (1MP;2 MP) tests through the pressure-specified sensory device (PSSD) on the cutaneous territory of the dorsal first web, hallux pulp, and medial calcaneal. In addition, patients were evaluated using the Semmes-Weinstein monofilament (SWM) No. 5.07 and tuning fork (128 Hz), which were used as normality parameters to detect the loss of protective sensibility. The same examinations were used to assess the control group (228 nondiabetic). Results: Altered values were observed for the static and moving tests over the three studied nerve territories. In comparing the sensibility threshold between diabetic patients who were sensitive and nonsensitive to SWM 5.07, we observed that this filament is not the most indicated for identifying the loss of sensibility in these patients. The prevalence of patients at risk varied between 85 and 89%. The biochemical marker associated with these high rates was HbA1c (p = 0.02). Conclusions: Numeric quantification of the pressure threshold allowed us to determine the functional deficit of nerve fibers. Our findings suggest that the neurosensory device should be used as an adjuvant tool to evaluate the degree of loss of sensation on the skin. (C) 2019 Published by Elsevier B.V.
  • article 21 Citação(ões) na Scopus
    Mechanical evaluation of the resistance and elastance of post-burn scars after topical treatment with tretinoin
    (2011) DEMATTE, Maria Fernanda; GEMPERLI, Rolf; SALLES, Alessandra Grassi; DOLHNIKOFF, Marisa; LANCAS, Tatiana; SALDIVA, Paulo Hilario Nascimento; FERREIRA, Marcus Castro
    OBJECTIVE: After burn injuries, scarred skin lacks elasticity, especially in hypertrophic scars. Topical treatment with tretinoin can improve the appearance and quality of the skin (i.e., texture, distensibility, color, and hydration). The objective of this prospective study was to examine the effects of treatment with 0.05% tretinoin for one year on the biomechanical behavior and histological changes undergone by facial skin with post-burn scarring. Setting: Tertiary, Institutional. METHOD: Fifteen female patients who had suffered partial thickness burns with more than two years of evolution were selected. Skin biopsies were obtained initially and after one year of treatment. The resistance and elastance of these skin biopsies were measured using a mechanical oscillation analysis system. The density of collagen fibers, elastic fibers, and versican were determined using immunohistochemical analysis. RESULTS: Tretinoin treatment significantly lowered skin resistance and elastance, which is a result that indicates higher distensibility of the skin. However, tretinoin treatment did not significantly affect the density of collagen fibers, elastic fibers, or versican. CONCLUSION: Topical tretinoin treatment alters the mechanical behavior of post-burn scarred skin by improving its distensibility and thus leads to improved quality of life for patients.
  • article
    Estudo epidemiológico de queimaduras em crianças atendidas em hospital terciário na cidade de São Paulo
    (2012) MILLAN, Lincoln Saito; GEMPERLI, Rolf; TOVO, Fernando Melhado; MENDAÇOLLI, Thiago Jung; GOMEZ, David Souza; FERREIRA, Marcus Castro
    BACKGROUND: This study describes the experience with the care of burned children in the Burn Treatment Unit, Division of Plastic Surgery, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (Hospital of the Faculty of Medicine, University of São Paulo - HCFMUSP) over 15 consecutive months. METHODS: The data of 98 patients up to 13 years of age treated in the Burn Treatment Unit of HCFMUSP from October 2009 to December 2010 were analyzed. RESULTS: The average age of the children was 5.2 years; 67 (68.4%) were boys. Accidents were responsible for burns in 93 (94.9%) cases, whereas 1 (1%) case of burns was caused by aggression. There was a higher incidence of burns in children under 2 years of age. The main agent causing burns was hot liquids (48%), followed by fire (17%) and hot solids (17%). The mean body surface area affected by second- and third-degree burns was 10%. Six (6.1%) patients had burns over more than 20% of their body surface area - 5 (83.3%) of them had burns due to burning alcohol and 1 (16.7%) due to scalding water. All cases in which more than 30% of the body surface was affected by second- and third-degree burns were due to alcohol burns. CONCLUSIONS: This survey demonstrates the importance of burn injuries in pediatric patients. The dataset suggests prevention efforts should focus on the domestic environment, particularly against scalding in children less than 5 years of age. In children older than 5 years, prevention programs should focus on both domestic and extradomestic environments.
  • article
    Tratamento da ptose mamária e hipomastia utilizando técnica de mamoplastia com pedículo súpero-medial e implante mamário
    (2012) WADA, Alexandre; MILLAN, Lincoln Saito; GALLAFRIO, Samuel Terra; GEMPERLI, Rolf; FERREIRA, Marcus Castro
    BACKGROUND: One-stage treatment of breast ptosis with hypomastia using mastopexy techniques combined with breast augmentation is often believed to have the potential for more serious complications than when the procedures are performed separately. However, available data show that the incidence of complications associated with the combined treatment is similar to that of both procedures performed separately. Several authors have developed standard and specific care techniques that facilitate the safe use of this combined technique. The aim of this study is to describe the surgical technique used for breast augmentation in patients with breast ptosis, as well as the incidence of complications and surgical revision. METHODS: The incidence of complications and surgical revision was analyzed in 27 patients who underwent one-stage mastopexy combined with breast augmentation using the superomedial pedicle technique, between 2005 and 2010. RESULTS: There were no immediate complications that required early reoperations. Three (11.1%) patients had slight dehiscence of the suture at the inverted-T junction, with spontaneous resolution. One (3.7%) patient developed capsular contracture 1 year after the operation. Four (14.8%) patients underwent scar revision procedures. A history of smoking was associated with a four-fold increase in the incidence of suture dehiscence and doubled the number of scar revision procedures; however, the difference was not statistically significant. CONCLUSIONS: The mastopexy technique combined with breast augmentation using the superomedial pedicle technique was effective and safe for the treatment of breast ptosis with hypomastia.
  • article
    Análise comparativa da evolução e das complicações pós-operatórias nas cirurgias plásticas do contorno corporal em pacientes idosos e jovens com perda ponderal maciça
    (2012) SMANIOTTO, Pedro Henrique de Souza; SAITO, Fabio Lopes; FORTES, Fernando; SCOPEL, Simone Orpheu; GEMPERLI, Rolf; FERREIRA, Marcus Castro
    BACKGROUND: Increasing numbers of procedures are being used to treat elderly ex-obese patients after bariatric therapies. However, reliable data regarding the evolution and complications of this population are scarce in the literature. In this study, we aimed to analyze the evolution and complications of abdominoplasty performed in patients with advanced age after massive weight loss and compare them to the corresponding data from younger patients. METHODS: We retrospectively reviewed patients who experienced massive weight loss and underwent surgery for abdominal contouring between July 2005 and July 2011 in the State Hospital Sapopemba (HESAP). An age of ≥ 60 years was used as a criterion for advanced age, in order to divide patients into groups to analyze the postoperative period and complications of abdominoplasty performed after massive weight loss. RESULTS: We analyzed 264 patients, 19 of whom were 60-75 years of age (Group I) and 245 of whom were 22-59 years of age (Group J). Group I had a major complication rate of 10.5% (P > 0.999) and a minor complication rate of 41.1% (P = 0.280), whereas Group J had a major complication rate of 10.6% (P > 0.999) and a minor complication rate of 30.2% (P = 0.280). CONCLUSIONS: Patients ≥ 60 years of age do not have a higher rate of complications than younger patients after abdominoplasty.