PEDRO RODRIGUES GENTA
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/63, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/63, Hospital das Clínicas, Faculdade de Medicina - Líder
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
bookPart Efeitos da obesidade no pulmão|asma, apneia do sono e hipoventilação(2015) GENTA, Pedro Rodrigues; SCHORR, Fabíola; BEZERRA, Lia Belchior Mendes; LORENZI FILHO, GeraldoconferenceObject Effects Of Oropharyngeal Exercises On Snoring: A Randomized Trial(2015) IETO, V.; KAYAMORI, F.; MONTES, M. I.; HIRATA, R. P.; GREGORIO, M. G.; ALENCAR, A. M.; DRAGER, L. F.; GENTA, P. R.; LORENZI-FILHO, G.bookPart Apneia Obstrutiva do Sono(2015) SANTANA, Alfredo Nicodemos da Cruz; GENTA, Pedro Rodrigues; LORENZI FILHO, Geraldo- Critical evaluation of screening questionnaires for obstructive sleep apnea in patients undergoing coronary artery bypass grafting and abdominal surgery(2015) NUNES, Flavia S.; DANZI-SOARES, Naury J.; GENTA, Pedro R.; DRAGER, Luciano F.; CESAR, Luiz A. M.; LORENZI-FILHO, GeraldoObstructive sleep apnea (OSA) is an independent risk factor for complications after surgery. However, OSA remains largely under recognized, and questionnaires designed to detect OSA have shown inconsistent results. Patients with cardiovascular diseases may not present with the typical symptoms of OSA. We therefore sought to compare the performance of screening questionnaires of patients referred for coronary artery bypass grafting (CABG) versus abdominal surgery (Abd surgery). We studied 40 consecutive patients referred for CABG [29 men; age 56 +/- 7 years; body mass index (BMI) 30 +/- 4 kg/m(2)], and 41 referred to Abd Surgery matched for age, gender, and BMI (28 men; age 56 +/- 8 years; BMI 29 +/- 5 kg/m(2)). All patients were evaluated with validated questionnaires to predict OSA (STOP-Bang and Berlin), Epworth sleepiness scale (ESS) and full overnight polysomnography. The prevalence of OSA (apnea-hypopnea index a parts per thousand yen15 events/hour) in the CABG and Abd surgery groups was similar (52 and 41 %, respectively, p = 0.32). The Berlin questionnaire showed similar sensitivity (67 vs. 82 %, p = 0.17) but lower specificity in the CABG group (26 vs. 62 %, p = 0.02). The STOP-BANG questionnaire had a high sensitivity (90 vs. 94 %, p = 0.42) but low specificity (5 vs. 13 %, p = 0.25) in the CABG and Abd surgery groups, respectively. Patients referred for CABG slept less (323 [285-376] vs. 378 [308-415] minutes, p = 0.04) but had lower levels of daytime sleepiness than Abd surgery patients had (ESS, 6 +/- 4 vs. 9 +/- 5; p = 0.01, respectively). Presenting clinical characteristics of OSA are modulated by the population evaluated and may affect the performance of screening questionnaires.
conferenceObject Upper Airway Collapsibility Assessed By Negative Expiratory Pressure While Awake Is Associated With Tongue Dimensions And Hyoid Position(2015) HIRATA, R. P.; KAYAMORI, F.; SCHORR, F.; GENTA, P. R.; MORIYA, H. T.; ROMANO, S.; INSALACO, G.; OLIVEIRA, L. F.; LORENZI-FILHO, G.- Effects of Oropharyngeal Exercises on Snoring A Randomized Trial(2015) IETO, Vanessa; KAYAMORI, Fabiane; MONTES, Maria I.; HIRATA, Raquel P.; GREGORIO, Marcelo G.; ALENCAR, Adriano M.; DRAGER, Luciano F.; GENTA, Pedro R.; LORENZI-FILHO, GeraldoBACKGROUND: Snoring is extremely common in the general population and may indicate OSA. However, snoring is not objectively measured during polysomnography, and no standard treatment is available for primary snoring or when snoring is associated with mild forms of OSA. This study determined the effects of oropharyngeal exercises on snoring in minimally symptomatic patients with a primary complaint of snoring and diagnosis of primary snoring or mild to moderate OSA. METHODS: Patients were randomized for 3 months of treatment with nasal dilator strips plus respiratory exercises (control) or daily oropharyngeal exercises (therapy). Patients were evaluated at study entry and end by sleep questionnaires (Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index) and full polysomnography with objective measurements of snoring. RESULTS: We studied 39 patients (age, 46 +/- 13 years; BMI, 28.2 +/- 3.1 kg/m(2); apnea-hypopnea index (AHI), 15.3 +/- 9.3 events/h; Epworth Sleepiness Scale, 9.2 +/- 4.9; Pittsburgh Sleep Quality Index, 6.4 +/- 3.3). Control (n = 20) and therapy (n = 19) groups were similar at study entry. One patient from each group dropped out. Intention-to-treat analysis was used. No significant changes occurred in the control group. In contrast, patients randomized to therapy experienced a significant decrease in the snore index (snores. 36 dB/h), 99.5 (49.6-221.3) vs 48.2 (25.5-219.2); P = .017 and total snore index (total power of snore/h), 60.4 (21.8-220.6) vs 31.0 (10.1-146.5); P = .033. CONCLUSIONS: Oropharyngeal exercises are effective in reducing objectively measured snoring and are a possible treatment of a large population suffering from snoring.
conferenceObject Tongue Shape And Pharyngeal Critical Closing Pressure(2015) GENTA, P. R.; KAYAMORI, F.; SCHORR, F.; MORIYA, H.; GEBRIM, E.; LORENZI-FILHO, G.