FELIX JOSE ALVAREZ RAMIRES

(Fonte: Lattes)
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Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/11 - Laboratório de Cirurgia Cardiovascular e Fisiopatologia da Circulação, Hospital das Clínicas, Faculdade de Medicina

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Agora exibindo 1 - 10 de 29
  • conferenceObject
    Impact of sympathectomy upon myocardium
    (2019) PESSOA, F. Fernanda; JORDAO, M. R.; FONSECA, K. C. B.; ZANONI, F.; SALEMI, V. M. C.; RIBEIRO, O. N.; SOUZA, L. E.; FERNANDES, F.; IRIGOYEN, M. C.; MOREIRA, L. F. P.; MADY, C.; RAMIRES, F. J. A.
  • conferenceObject
    Effects of sympathectomy on myocardium
    (2014) JORDAO, M.; RAMIRES, F.; PESSOA, F.; FONSECA, K.; ZANONI, F.; SOUZA, L.; SALEMI, V.; MADY, C.
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    Effect of the angiotensin receptor neprilysin inhibitor LCZ696 compared with enalapril according to systolic blood pressure in PARADIGM-HF
    (2015) BOHM, M.; REFSGAARD, J.; RAMIRES, F. J. A.; ROULEAU, J. L.; SOLOMON, S. D.; SWEDBERG, K.; ZILE, M.; SHI, V. C.; PACKER, M.; MCMURRAY, J. J. V.
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    Brain natriuretic peptide predicts mortality in patients undergoing pericardiectomy for constrictive pericarditis
    (2014) MELO, D. T. P.; FERNANDES, F.; GUALANDRO, D. M.; SALEMI, V. M. C.; OLIVETTI, N. Q. S.; BUCK, P. C.; DIAS, R. R.; RAMIRES, F. J. A.; CARAMELLI, B.; MADY, C.
  • conferenceObject
    IMPACT OF AIR POLLUTION ON MYOCARDIAL REMODELING IN CHAGA'S DISEASE
    (2019) FONSECA, Keila; PESSOA, Fernanda; MADY, Charles; HOTTA, Viviane; RIBEIRO, Orlando N.; FERNANDES, Fabio; IANNI, Barbara; SALDIVA, Paulo; RAMIRES, Felix
  • conferenceObject
    Myocardial Stiffness evaluation by shear wave elastography in transthyretin amyloidosis with and without cardiac involvement
    (2023) ALENCAR NETO, A. C. Comte de; CAFEZEIRO, C. R. F. C. Caio Reboucas Fonseca; BUENO, B. V. K. B. Bruno Vaz Kerges; RISSATO, J. H. R. Joao Henrique; HOTTA, V. T. H. Viviane Tiemi; ALENCAR FILHO, A. C. A. F. Aristoteles Comte De; PEREIRA, F. L. P. Fernando Linhares; COUCEIRO, K. C. Katia; ROCHITTE, C. E. R. Carlos Eduardo; BARBOSA, J. M. B. B. Joao Marcos Bemfica; SOARES JUNIOR, J. S. J. Jose; RAMIRES, F. J. A. R. Felix Jose Alvarez; KALIL FILHO, R. K. F. Roberto; MATHIAS JUNIOR, W. M. J. Wilson; FERNANDES, F. F. Fabio
  • conferenceObject
    Lack of Effect of Simvastatin on Structural Remodeling in Animal Model of Chagas Cardiomyopathy
    (2012) IANNI, Barbara M.; RAMIRES, Felix J. A.; SALEMI, Vera M. C.; FERNANDES, Fabio; OLIVEIRA, Adriana M.; PESSOA, Fernanda G.; FONSECA, Keila C. B.; ARTEAGA, Edmundo; NASTARI, Luciano; MADY, Charles
    Purpose: Chagas cardiomyopathy(CM) is characterized by a large amount of fibrosis and inflamation. As simvastatin (simva) has anti-inflamatory effects, we hypothetized that it could be an important drug in the treatment of patients with CM. The purpose was to evaluate simva in the myocardium remodeling and inflammation in na animal model of CM. Methods: 123 hamsters were divided: C-controls(25), CSimva-controls with simva 10mg/Kg/day(25), Simva1-infected treated from beginning with the same dose of simva(25), Simva2-infected treated after 4 months(24); Infect-untreated(24). Follow-up of 10 months. Interstitial collagen volume fraction (ICVF) RV and LV measured using videomorphometry and picrosirius red stained heart. Metalloproteinase9 (MMP9) was obtained by zymography. Gene expression of TNFalpha, IFNgamma, IL10 by real time PCR and ΔCt. Survival by Kaplan-Meier and log rank. Comparison between groups by Kruskal-Wallis; p≤0.05. Results: Infected animals Simva1=189±133 days Simva2=150±124; Infect=138±123) lived less than controls (C=257±80; CSimva=283±58)(p≤0.05) with no difference among infected. ICVF-RV(%) was greater in infected groups (Simva1=3.88±1.14, Simva2=2.22±0.64; Infect=4.38±0.83) than in controls C=1.12±0.31; CSimva=2.18±0.73)(p≤0.05)with no difference among infected groups. ICVF-LV(%) was greater in infected animals (Simva1=1.83±1.01, Simva2=1.52±0.93; Infect=3.01±0.66) than in controls (C=0.68±0.31; CSimva=0.81±0.28)(p≤0.05) with no difference among infected. MMP9 was higher in infected groups (Simva1=2394±2441, Simva2=5673±4091; Infect=2392±2042) compared to controls (C=954±2332; CSimva=454±1123)(p≤0.05) with no difference among infected. TNFalpha did not have difference among infected groups (Simva1=5.33±3.66, Simva2=4.44±2.17; Infect=6.13±3.24). IFNgamma in infected groups (Simva1=5.47±3.56, Simva2=4.46±2.08; Infect=4.21±2.09) was higher than in controls (C=8.50±2.59; CSimva=6.84±2.53)(p≤0.05) with no difference among infected. IL10 in infected animals (Simva1=9.07±4.62, Simva2=7.76±4.77; Infect=8.11±4.48) did not have difference and the values were greater than controls (C=14.11±4.40; CSimva=12.55±3.90)(p≤0.05). Conclusions: Simva did not attenuate deposition of interstitial collagen, did not change dynamics of collagen degradation, did not decrease inflammation, and did not reduce mortality.
  • conferenceObject
    Influence of increasing age in hospital readmission and mortality rate at 180 days in patients hospitalized for decompensated heart failure
    (2019) ISSA, Victor; LLORET, Rafael; TAMBURIM, Barbara; RAMIRES, Felix; AMORIM, Carolina; CORRAL, Semeia
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    Influence of renal dysfunction on the increase in rehospitalization rates and mortality at 180 days in patients hospitalized for decompensated heart failure
    (2019) ISSA, Victor; LLORET, Rafael; TAMBURIM, Barbara; AMORIM, Carolina; CORRAL, Semeia; RAMIRES, Felix
  • conferenceObject
    Influence of air pollution upon myocardial remodeling
    (2013) OLIVEIRA, A. M.; RAMIRES, F.; FONSECA, K. C. B.; SALEMI, V. M.; PESSOA, F. G.; FERNANDES, F.; SALDIVA, P.; MADY, C.