MATHEUS SCHMIDT SOARES
Projetos de Pesquisa
Unidades Organizacionais
LIM/26 - Laboratório de Pesquisa em Cirurgia Experimental, Hospital das Clínicas, Faculdade de Medicina
3 resultados
Resultados de Busca
Agora exibindo 1 - 3 de 3
- Psychosurgery for schizophrenia: history and perspectives(2013) SOARES, Matheus Schmidt; PAIVA, Wellingson Silva; GUERTZENSTEIN, Eda Z.; AMORIM, Robson Luis; BERNARDO, Luca Silveira; PEREIRA, Jose Francisco; FONOFF, Erich Talamoni; TEIXEIRA, Manoel JacobsenFollowing the early studies of Moniz and Lima, psychosurgery had considerable scientific credibility until the advent of modern antipsychotics in the mid 1950s. Thereafter, psychosurgery was almost abandoned in large medical centers as a common treatment for schizophrenia, although is still used for some affective and anxiety disorders. We reviewed relevant papers cited in the Medline/Index Medicus, Cochrane, and Scielo databases from 1930 to 2012. In our review of the literature, we show from recent studies that there are still many patients with schizophrenia who have serious deficits even after being treated with current noninvasive therapies. The value of psychosurgery remains controversial. There are no data available to support the use of stereotactic procedures for schizophrenia. Well designed controlled trials are needed to establish the effectiveness of psychosurgery in patients with schizophrenia.
- Letter to the Editor Regarding ""Subdural Hematoma in Patients with Hematologic Malignancies: An Outcome Analysis and Examination of Risk Factors of Operative and Nonoperative Management""(2020) FAGUNDES, Caroline Ferreira; SOUZA, Matheus Rodrigues de; SOARES, Matheus Schmidt; PAIVA, Wellingson Silva
- Morbidity following sural nerve harvesting: A prospective study(2012) MARTINS, Roberto S.; BARBOSA, Rafael A.; SIQUEIRA, Mario G.; SOARES, Matheus S.; HEISE, Carlos Otto; FORONI, Luciano; TEIXEIRA, Manoel J.Objective: To evaluate donor site morbidity following sural nerve harvesting, with special attention to the recovery of sensory loss. Methods: We prospectively followed 38 subjects who underwent sural nerve harvest, including two with bilateral nerve excision. Symptoms related to sural nerve excision were evaluated and demarcation of the area with reduced touch sensation was quantified. Assessments were performed periodically up to 1 year after surgery and the results of different sensory evaluations were compared. Results: A significant reduction of sensory deficit was identified between consecutive evaluations (p < 0.05). Decreases of 26.85%, 20.69% and 24.29% were observed 3, 6 and 12 months after surgery, respectively. Shock-like pain (7.5%), stabbing pain (7.5%), and numbness (5%) were the most frequently reported symptoms. All symptoms were brief and resolved spontaneously 3-6 months after surgery. Conclusion: Sural nerve harvest can be performed with acceptable morbidity. When present, symptoms resolve between the third and sixth month after surgery and a significant reduction of sensory loss in the area innervated by the sural nerve was observed during the first year of follow-up.