JOSE SOARES JUNIOR

(Fonte: Lattes)
Índice h a partir de 2011
7
Lattes
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina

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Autor: GIORGI, Maria Clementina P. × Autor e Coautores FMUSP-HC Normalizados: JOSE CLAUDIO MENEGHETTI ×

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Agora exibindo 1 - 7 de 7
  • bookPart
  • bookPart
    Inflamação e infecção cardiovasculares
    (2017) MENEGHETTI, José Cláudio; JúNIOR, José Soares; IZAKI, Marisa; GIORGI, Maria Clementina P.
  • article 6 Citação(ões) na Scopus
    Low-carbohydrate diet versus euglycemic hyperinsulinemic clamp for the assessment of myocardial viability with F-18-fluorodeoxyglucose-PET: a pilot study
    (2014) SOARES JR., Jose; RODRIGUES FILHO, Filadelfo; IZAKI, Marisa; GIORGI, Maria Clementina P.; CATAPIRRA, Rosa M. A.; ABE, Rubens; VINAGRE, Carmen G. C. M.; CERRI, Giovanni G.; MENEGHETTI, Jose Claudio
    Positron emission tomography with F-18-fluorodeoxyglucose (FDG-PET) is considered the gold standard for myocardial viability. A pilot study was undertaken to compare FDG-PET using euglycemic hyperinsulinemic clamp before F-18-fluorodeoxyglucose (F-18-FDG) administration (PET-CLAMP) with a new proposed technique consisting of a 24-h low-carbohydrate diet before F-18-FDG injection (PET-DIET), for the assessment of hypoperfused but viable myocardium (hibernating myocardium). Thirty patients with previous myocardial infarction were subjected to rest Tc-99m-sestamibi-SPECT and two F-18-FDG studies (PET-CLAMP and PET-DIET). Myocardial tracer uptake was visually scored using a 5-point scale in a 17-segment model. Hibernating myocardium was defined as normal or mildly reduced metabolism (F-18-FDG uptake) in areas with reduced perfusion (Tc-99m-sestamibi uptake) since F-18-FDG uptake was higher than the degree of hypoperfusion-perfusion/metabolism mismatch indicating a larger flow defect. PET-DIET identified 79 segments and PET-CLAMP 71 as hibernating myocardium. Both methods agreed in 61 segments (agreement = 94.5 %, kappa = 0.78). PET-DIET identified 230 segments and PET-CLAMP 238 as nonviable. None of the patients had hypoglycemia after DIET, while 20 % had it during CLAMP. PET-DIET compared with PET-CLAMP had a good correlation for the assessment of hibernating myocardium. To our knowledge, these data provide the first evidence of the possibility of myocardial viability assessment with this technique.
  • bookPart
    Cintilografia cardíaca com pirofosfato
    (2017) MENEGHETTI, José Cláudio; JúNIOR, José Soares; IZAKI, Marisa; GIORGI, Maria Clementina P.
  • bookPart
    Avaliação da função ventricular
    (2017) MENEGHETTI, José Cláudio; JúNIOR, José Soares; IZAKI, Marisa; GIORGI, Maria Clementina P.
  • bookPart
    Viabilidade miocárdica
    (2017) MENEGHETTI, José Cláudio; JúNIOR, José Soares; IZAKI, Marisa; GIORGI, Maria Clementina P.
  • bookPart
    Cintilografia de perfusão miocárdica
    (2017) MENEGHETTI, José Cláudio; JúNIOR, José Soares; IZAKI, Marisa; GIORGI, Maria Clementina P.; PADILHA, Bruno Gomes