JOSE SOARES JUNIOR
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
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conferenceObject 18F-FDG PET/CT Findings vs. Histology of Surgically Resected Cardiac Valves in Patients With Infective Endocarditis.(2018) CAMARGO, Raphael A.; CASTELLI, Jussara B.; BITTENCOURT, Marcio S.; AYABE, Daniel; PAIXAO, Milena R.; FELICIO, Marilia F.; SOEIRO, Alexandre M.; GONCALVES, Luis Fernando T.; V, Tania Strabelli; SOARES JR., Jose; BUCHPIGUEL, Carlos A.; MANSUR, Alfredo J.; TARASOUTCHI, Flavio; OLIVEIRA JR., Mucio T.; MENEGHETTI, Claudio; GUALANDRO, Daniele M.; POCEBON, Lucas; BLANKSTEIN, Ron; ALAVI, Abass; SICILIANO, Rinaldo F.conferenceObject Rheumatic myocarditis: a poorly recognized etiology of left ventricular dysfunction in valvular heart disease patients(2021) ROSA, V. Emer Egypto; LOPES, M. P.; SPINA, G. S.; SOARES JR., J.; SALAZAR, D.; ROMERO, C. E.; LOTTEMBERG, M. P.; SANTIS, A. De; PIRES, L. J. N. T.; GONCALVES, L. F. T.; FERNANDES, J. R. C.; SAMPAIO, R. O.; TARASOUTCHI, F.- Rheumatic Myocarditis: A Poorly Recognized Etiology of Left Ventricular Dysfunction in Valvular Heart Disease Patients(2021) ROSA, Vitor Emer Egypto; LOPES, Mariana Pezzute; SPINA, Guilherme Sobreira; SOARES JUNIOR, Jose; SALAZAR, David; ROMERO, Cristhian Espinoza; LOTTENBERG, Marcos Pita; SANTIS, Antonio de; PIRES, Lucas Jose Neves Tachotti; GONCALVES, Luis Fernando Tonello; FERNANDES, Joao Ricardo Cordeiro; SAMPAIO, Roney Orismar; TARASOUTCHI, FlavioBackground: Heart failure occurs in similar to 10% of patients with acute rheumatic fever (RF), and several studies have shown that cardiac decompensation in RF results primarily from valvular disease and is not due to primary myocarditis. However, the literature on this topic is scarce, and a recent case series has shown that recurrent RF can cause ventricular dysfunction even in the absence of valvular heart disease. Methods: The present study evaluated the clinical, laboratory and imaging characteristics of 25 consecutive patients with a clinical diagnosis of myocarditis confirmed by 18F-FDG PET/CT or gallium-67 cardiac scintigraphy and RF reactivation according to the revised Jones Criteria. Patients underwent three sequential echocardiograms at (1) baseline, (2) during myocarditis and (3) post corticosteroid treatment. Patients were divided according to the presence (Group 1) or absence (Group 2) of reduced left ventricular ejection fraction (LVEF) during myocarditis episodes. Results: The median age was 42 (17-51) years, 64% of patients were older than 40 years, and 64% were women. Between Group 1 (n = 16) and in Group 2 (n = 9), there were no demographic, echocardiographic or laboratory differences except for NYHA III/IV heart failure (Group 1: 100.0% vs. Group 2: 50.0%; p = 0.012) and LVEF (30 [25-37] vs. 56 [49-62]%, respectively; p < 0.001), as expected. Group 1 patients showed a significant reduction in LVEF during carditis with further improvement after treatment. There was no correlation between LVEF and valvular dysfunction during myocarditis. Among all patients, 19 (76%) underwent 18F-FDG PET/CT, with a positive scan in 68.4%, and 21 (84%) underwent gallium-67 cardiac scintigraphy, with positive uptake in 95.2%, there was no difference between these groups. Conclusion: Myocarditis due to rheumatic fever reactivation can cause left ventricular dysfunction despite valvular disease, and it is reversible after corticosteroid treatment.
- The Role of F-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in the Diagnosis of Left-sided Endocarditis: Native vs Prosthetic Valves Endocarditis(2020) CAMARGO, Raphael Abegao de; BITENCOURT, Marcio Sommer; MENEGHETTI, Jose Claudio; JR, Jose Soares; GONCALVES, Luis Fernando Tonello; BUCHPIGUEL, Carlos Alberto; PAIXAO, Milena Ribeiro; FELICIO, Marilia Francesconi; SOEIRO, Alexandre de Matos; STRABELLI, Tania Mara Varejao; MANSUR, Alfredo Jose; TARASOUTCHI, Flavio; JR, Mucio Tavares de Oliveira; CASTELLI, Jussara Bianchi; GUALANDRO, Danielle Menosi; POCEBON, Lucas Zoboli; BLANKSTEIN, Ron; ALAVI, Abass; MOORE, John Edmund; MILLAR, Beverley Cherie; SICILIANO, Rinaldo FocacciaBackground: F-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG-PET/CT) has emerged as a useful diagnostic tool for suspected infective endocarditis (IE) in patients with prosthetic valves or implantable devices. However, there is limited evidence regarding use of F-18-FDG-PET/CT for the diagnosis of native valve endocarditis (NVE). Methods: Between 2014 and 2017, 303 episodes of left-sided suspected IE (188 prosthetic valves/ascending aortic prosthesis and 115 native valves) were studied. F-18-FDG-PET/CT accuracy was determined in the subgroups of patients with NVE and prosthetic valve endocarditis (PVE)/ascending aortic prosthesis infection (AAPI). Associations between inflammatory infiltrate patterns and F-18-FDG-PET/CT uptake were investigated in an exploratory ad hoc histological analysis. Results: Among 188 patients with PVE/AAPI, the sensitivity, specificity, and positive and negative predictive values of F-18-FDG-PET/CT focal uptake were 93%, 90%, 89%, and 94%, respectively, while among 115 patients with NVE, the corresponding values were 22%, 100%, 100%, and 66%. The inclusion of abnormal F-18-FDG cardiac uptake as a major criterion at admission enabled a recategorization of 76% (47/62) of PVE/AAPI cases initially classified as ""possible"" to ""definite"" IE. In the histopathological analysis, a predominance of polymorphonuclear cell inflammatory infiltrate and a reduced extent of fibrosis were observed in the PVE group only. Conclusions: Use of F-18-FDG-PET/CT at the initial presentation of patients with suspected PVE increases the diagnostic capability of the modified Duke criteria. In patients who present with suspected NVE, the use of F-18-FDG-PET/CT is less accurate and could only be considered a complementary diagnostic tool for a specific population of patients with NVE.
- Cardiac Magnetic Resonance and Positron Emission Tomography in the Diagnosis and Follow-Up of Acute Rheumatic Fever - Case Report(2023) SALAZAR, David; ROMERO, Cristhian Espinoza; LOPES, Mariana Pezzute; BRANCO, Carlos Eduardo de Barros; SOARES JUNIOR, José; SANTIS, Antonio de; SAMPAIO, Roney Orismar; TARASOUTCHI, Flávio
conferenceObject Diagnostic value of Positron emission tomography (PET/CT) in native and prosthetic infective endocarditis(2017) CAMARGO, R. A.; SICILIANO, R. F.; PAIXAO, M. R.; SOEIRO, A. M.; SOARES JR., J.; FELICIO, M. F.; STRABELLI, T. M. V.; BUCHPIGUEL, C. A.; ALAVI, A.; TONELLO, L.; MANSUR, A. J.; TARASOUTCHI, F.; OLIVEIRA JR., M. T.; MENEGHETTI, J. C.