UENIS TANNURI

(Fonte: Lattes)
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Departamento de Pediatria, Faculdade de Medicina - Docente
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/30 - Laboratório de Investigação em Cirurgia Pediát, Hospital das Clínicas, Faculdade de Medicina - Líder

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Agora exibindo 1 - 10 de 25
  • bookPart
    Dilatação congênita das vias biliares
    (2020) TANNURI, Uenis
  • bookPart
  • bookPart
    Anomalias do arco aórtico
    (2020) TANNURI, Uenis; TANNURI, Ana Cristina Aoun
  • bookPart
    Transplante de fígado na criança
    (2020) TANNURI, Ana Cristina Aoun; TANNURI, Uenis
  • bookPart
    Afecções congênitas geniturinárias
    (2020) RICARDI, Luiz Roberto Schlaich; TANNURI, Uenis
  • article 0 Citação(ões) na Scopus
    Sepsis and cirrhosis in growing animals: description of a new experimental model and its pathological and immunological reliability
    (2020) MORAES, Pedro Augusto Dantas de; TANNURI, Ana Cristina Aoun; RIOS, Livio Moreira; PEES, Vitor Ribeiro; GONCALVES, Josiane de Oliveira; SERAFINI, Suellen; TANNURI, Uenis
    OBJECTIVES: In cirrhotic children, infection events and sepsis are more frequent and more severe due to immune dysfunction. The objectives of the current study were therefore to develop an experimental model of infection and sepsis in cirrhotic weaning growing rats, by the use of bile duct ligation (BDL) and cecal ligation and puncture (CLP). Additionally, the correlation of the clinico-histopathological data and serial cytokine levels in septic cirrhotic and non-cirrhotic animals was studied. METHODS: Young Wistar rats of age 21 days and of weight between 70-90 g were divided into 12 groups according to the surgical procedure performed: sham (sacrificed after 2 or 4 weeks), BDL (sacrificed after 2 or 4 weeks), CLP (2- or 4-week old animals sacrificed after 12 or 24 hours), BDL+CLP (2- or 4-week old animals sacrificed after 12 hours). Histopathological studies and determination of serum levels of cytokines IL-1 beta, IL10, and TNF-alpha, for studies of systemic infection, were performed. Murine sepsis scores (MSS) based on the clinical aspects just before euthanasia were also included. RESULTS: A transitory increase in IL-1, IL-10, and TNF-alpha levels was observed, with different patterns according to the groups. Two-hit groups tended to present with higher values of serum cytokines and histopathological scores than their septic non-cirrhotic counterparts. There was a correlation between mortality rate and MSS (p<0.0001). CONCLUSION: The model is feasible and may be utilized in studies on liver cirrhosis and infection in growing animals.
  • bookPart
    Afecções cirúrgicas causadas por parasitas
    (2020) TANNURI, Uenis
  • bookPart
  • article 5 Citação(ões) na Scopus
    Non-Alcoholic Cirrhosis and Heart Rate Variability: A Systematic Mini-Review
    (2020) AMARAL, Joice Anaize Tonon do; SALATINI, Renata; ARAB, Claudia; ABREU, Luiz Carlos; VALENTI, Vitor E.; MONTEIRO, Carlos B. M.; TANNURI, Uenis; TANNURI, Ana Cristina Aoun
    Background and Objectives: Cirrhosis is a liver disease that causes about one million deaths annually worldwide. The estimated cirrhosis prevalence ranges from 4.5-9.5% in the general population. Up to 40% of cirrhotic patients are asymptomatic and may be diagnosed late. Studies have described the importance of the functions of the liver and autonomic nervous system (ANS) and their relationship. There is limited information available on non-alcoholic cirrhosis and heart rate variability (HRV), which is a measure of the ANS. This study aimed to evaluate cardiac autonomic modulation through HRV in non-alcoholic cirrhosis individuals reported in previous observational and clinical trial studies. Materials and Methods: We performed a systematic review according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) statement using the Medline, Scopus, and Web of Science electronic databases. Five studies were identified and reviewed. Results: HRV was decreased in patients with non-alcoholic cirrhosis, even in the first stage. Conclusions: HRV could be used as a complementary method to improve both the diagnosis and prognosis of non-alcoholic cirrhosis.
  • bookPart
    Atuação da equipe de enfermagem no centro cirúrgico pediátrico de alta complexidade
    (2020) FéLIX, Camila Prestes Martins; JESUS, Iranilda de; VELHOTE, Manoel Carlos Prieto; ROSSI, Suzana Guernieri; TANNURI, Uenis