ANA LUCIA DE SA PINTO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
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- Creatine Supplementation Associated or Not with Strength Training upon Emotional and Cognitive Measures in Older Women: A Randomized Double-Blind Study(2013) ALVES, Christiano Robles Rodrigues; MEREGE FILHO, Carlos Alberto Abujabra; BENATTI, Fabiana Braga; BRUCKI, Sonia; PEREIRA, Rosa Maria R.; PINTO, Ana Lucia de Sa; LIMA, Fernanda Rodrigues; ROSCHEL, Hamilton; GUALANO, BrunoPurpose: To assess the effects of creatine supplementation, associated or not with strength training, upon emotional and cognitive measures in older woman. Methods: This is a 24-week, parallel-group, double-blind, randomized, placebo-controlled trial. The individuals were randomly allocated into one of the following groups (n=14 each): 1) placebo, 2) creatine supplementation, 3) placebo associated with strength training or 4) creatine supplementation associated with strength training. According to their allocation, the participants were given creatine (4 x 5 g/d for 5 days followed by 5 g/d) or placebo (dextrose at the same dosage) and were strength trained or not. Cognitive function, assessed by a comprehensive battery of tests involving memory, selective attention, and inhibitory control, and emotional measures, assessed by the Geriatric Depression Scale, were evaluated at baseline, after 12 and 24 weeks of the intervention. Muscle strength and food intake were evaluated at baseline and after 24 weeks. Results: After the 24-week intervention, both training groups (ingesting creatine supplementation and placebo) had significant reductions on the Geriatric Depression Scale scores when compared with the non-trained placebo group (p = 0.001 and p = 0.01, respectively) and the non-trained creatine group (p < 0.001 for both comparison). However, no significant differences were observed between the non-trained placebo and creatine (p = 0.60) groups, or between the trained placebo and creatine groups (p = 0.83). Both trained groups, irrespective of creatine supplementation, had better muscle strength performance than the non-trained groups. Neither strength training nor creatine supplementation altered any parameter of cognitive performance. Food intake remained unchanged. Conclusion: Creatine supplementation did not promote any significant change in cognitive function and emotional parameters in apparently healthy older individuals. In addition, strength training per se improved emotional state and muscle strength, but not cognition, with no additive effects of creatine supplementation.
- Performing moderate to severe activity is safe and tolerable for healthy youth while wearing a cloth facemask(2023) MARTICORENA, Felipe Miguel; BARRETO, Gabriel Castanho; GUARDIEIRO, Natalia Mendes; ESTEVES, Gabriel Perri; OLIVEIRA, Tamires Nunes; OLIVEIRA, Luana Farias de; PINTO, Ana Lucia de Sa; RIANI, Luiz; PRADO, Danilo Mendes; SAUNDERS, Bryan; GUALANO, BrunoObjectiveTo investigate if a cloth facemask could affect physiological and perceptual responses to exercise at distinct exercise intensities in healthy young individuals. MethodsNine participants (sex, female/male: 6/3; age: 13 +/- 1 years; VO2peak: 44.5 +/- 5.5 mL/kg/min) underwent a progressive square-wave test at four intensities: (1) 80% of ventilatory anaerobic threshold (VAT), (2) VAT, and (3) 40% between VAT and _VO2peak wearing a triple-layered cloth facemask or not. Participants then completed a final stage to exhaustion at a running speed equivalent to the maximum achieved during the cardio-respiratory exercise test (Peak). Physiological, metabolic, and perceptual measures were measured. ResultsMask did not affect spirometry (forced vital capacity, peak expiratory flow, forced expiratory volume; all p >= 0.27), respiratory (inspiratory capacity, end-expiratory volume [EELV] to functional vital capacity ratio, EELV, respiratory frequency [Rf], tidal volume [VT], Rf/VT, end tidal carbo dioxide pressure, ventilatory equivalent to carbon dioxide ratio; all p >= 0.196), hemodynamic (heart rate, systolic and diastolic blood pressure; all p > 0.41), ratings of perceived exertion (p = 0.04) or metabolic measures (lactate; p = 0.78) at rest or at any exercise intensity. ConclusionsThis study shows that performing moderate to severe activity is safe and tolerable for healthy youth while wearing a cloth facemask.
- Similar Health Benefits of Endurance and High-Intensity Interval Training in Obese Children(2012) ARAUJO, Ana Carolina Corte de; ROSCHEL, Hamilton; PICANCO, Andreia Rossi; PRADO, Danilo Marcelo Leite do; VILLARES, Sandra Mara Ferreira; PINTO, Ana Lucia de Sa; GUALANO, BrunoPurpose: To compare two modalities of exercise training (i.e., Endurance Training [ET] and High-Intensity Interval Training [HIT]) on health-related parameters in obese children aged between 8 and 12 years. Methods: Thirty obese children were randomly allocated into either the ET or HIT group. The ET group performed a 30 to 60-minute continuous exercise at 80% of the peak heart rate (HR). The HIT group training performed 3 to 6 sets of 60-s sprint at 100% of the peak velocity interspersed by a 3-min active recovery period at 50% of the exercise velocity. HIT sessions last similar to 70% less than ET sessions. At baseline and after 12 weeks of intervention, aerobic fitness, body composition and metabolic parameters were assessed. Results: Both the absolute (ET: 26.0%; HIT: 19.0%) and the relative VO2 peak (ET: 13.1%; HIT: 14.6%) were significantly increased in both groups after the intervention. Additionally, the total time of exercise (ET: 19.5%; HIT: 16.4%) and the peak velocity during the maximal graded cardiorespiratory test (ET: 16.9%; HIT: 13.4%) were significantly improved across interventions. Insulinemia (ET: 29.4%; HIT: 30.5%) and HOMA-index (ET: 42.8%; HIT: 37.0%) were significantly lower for both groups at POST when compared to PRE. Body mass was significantly reduced in the HIT (2.6%), but not in the ET group (1.2%). A significant reduction in BMI was observed for both groups after the intervention (ET: 3.0%; HIT: 5.0%). The responsiveness analysis revealed a very similar pattern of the most responsive variables among groups. Conclusion: HIT and ET were equally effective in improving important health related parameters in obese youth.
- Effects of a new intervention based on the Health at Every Size approach for the management of obesity: The ""Health and Wellness in Obesity"" study(2018) ULIAN, Mariana Dimitrov; PINTO, Ana Jessica; SATO, Priscila de Morais; BENATTI, Fabiana B.; CAMPOS-FERRAZ, Patricia Lopes de; COELHO, Desire; ROBLE, Odilon J.; SABATINI, Fernanda; PEREZ, Isabel; ABURAD, Luiz; VESSONI, Andre; UNSAIN, Ramiro Fernandez; ROGERO, Marcelo Macedo; TOPORCOV, Tatiana Natasha; SA-PINTO, Ana Lucia de; GUALANO, Bruno; SCAGLIUSI, Fernanda B.Health at Every Size (R) (HAES (R)) is a weight-neutral approach focused on promoting healthy behaviors in people with different body sizes. This study examined multiple physiological, attitudinal, nutritional, and behavioral effects of a newly developed, intensive, interdisciplinary HAES (R)-based intervention in obese women. This was a prospective, seven-month, randomized (2: 1), controlled, mixed-method clinical trial. The intervention group (I-HAES (R); n = 39) took part in an intensified HAES (R)-based intervention comprising a physical activity program, nutrition counseling sessions, and philosophical workshops. The control group (CTRL; n = 19) underwent a traditional HAES (R)-based intervention. Before and after the interventions, participants were assessed for physiological, psychological, and behavioral parameters (quantitative data) and took part in focus groups (qualitative data). Body weight, body mass index, and waist and hip circumferences did not significantly differ within or between groups (P > 0.05). I-HAES (R) showed increased peak oxygen uptake and improved performance in the timed-stand test (P = 0.004 and P = 0.004, between-group comparisons). No significant within-or between-group differences were observed for objectively measured physical activity levels, even though the majority of the I-HAES (R) participants indicated that they were engaged in or had plans to include physical activity in their routines. I-HAES (R) resulted in improvements in eating attitudes and practices. The I-HAES (R) group showed significantly improved all Body Attitude Questionnaire subscale and all Figure Rating Scale scores (P <= 0.05 for all parameters, within-group comparisons), whereas the CTRL group showed slight or no changes. Both groups had significant improvements in health-related quality of life parameters, although the I-HAES (R) group had superior gains in the ""physical health,"" ""psychological health,"" and ""overall perception of quality of life and health"" (P = 0.05, 0.03, and 0.02, respectively, between-group comparisons) domains. Finally, most of the quantitative improvements were explained by qualitative data. Our results show that this new intensified HAES (R)-based intervention improved participants' eating attitudes and practices, perception of body image, physical capacity, and health-related quality of life despite the lack of changes in body weight and physical activity levels, showing that our novel approach was superior to a traditional HAES (R)-based program.
- I put it in my head that the supplement would help me: Open-placebo improves exercise performance in female cyclists(2019) SAUNDERS, Bryan; SAITO, Tiemi; KLOSTERHOFF, Rafael; OLIVEIRA, Luana Farias de; BARRETO, Gabriel; PERIM, Pedro; PINTO, Ana Jessica; LIMA, Fernanda; SAPINTO, Ana Lucia de; GUALANO, BrunoThis study investigated the effect of open-placebo on cycling time-trial (TT) performance. Twenty-eight trained female cyclists completed a 1-km cycling TT following a control session or an open-placebo intervention. The intervention consisted of an individual presentation, provided by a medic, in which the concept of open-placebo was explained to the participant, before she ingested two red and white capsules containing flour; 15 min later, they performed the TT. In the control session, the participant sat quietly for 20 min. Heart rate and ratings of perceived exertion (RPE) were monitored throughout exercise, while blood lactate was determined pre- and post-exercise. Post-exercise questionnaires were employed to gain insight into the perceived influence of the supplement on performance. Open-placebo improved time-to-completion (P = 0.039, 103.6 +/- 5.0 vs. 104.4 +/- 5.1 s, -0.7 +/- 1.8 s, -0.7 +/- 1.7%) and mean power output (P = 0.01, 244.8 +/- 34.7 vs. 239.7 +/- 33.2, +5.1 +/- 9.5 W) during the TT. Individual data analysis showed that 11 individuals improved, 13 remained unchanged and 4 worsened their performance with open-placebo. Heart rate, RPE and blood lactate were not different between sessions (all P>0.05). Positive expectation did not appear necessary to induce performance improvements, suggesting unconscious processes occurred, although a lack of an improvement appeared to be associated with a lack of belief. Open-placebo improved 1-km cycling TT performance in trained female cyclists. Although the intervention was successful for some individuals, individual variation was high, and some athletes did not respond or even performed worse. Thus, open-placebo interventions should be carefully considered by coaches and practitioners, while further studies are warranted.