PEDRO CARUSO
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
28 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 28
conferenceObject Diaphragmatic dysfunction in interstitial lung disease: An ultrasonography study(2014) SANTANA, Pauliane Vieira; PRINA, Elena; PLETSCH, Renata; FERREIRA, Jeferson; PEREIRA, Mayra Caleff; US, Andre Apanav; TREVISAN, Patricia; ALBUQUERQUE, Andre P.; CARVALHO, Carlos Roberto R.; CARUSO, Pedro- Regional ventilation of patients with hemidiaphragm paralysis by electrical impedance tomography(2015) PEREIRA, Mayra Caleffi; TORSANI, Vinicius; APANAVICIUS, Andre; FERREIRA, Jeferson George; IAMONTI, Vinicius C.; AMATO, Marcelo Britto Passos; CARVALHO, Carlos Roberto Ribeiro de; ALBUQUERQUE, Andre Luis Pereira de; CARUSO, Pedro
- Comparison of thoracoabdominal synchrony using two methods in healthy subjects, chronic obstructive and interstitial lung disease(2016) PEREIRA, Mayra Caleffi; FERREIRA, Jeferson; IAMONTI, Vinicius; TREVISAN, Patricia; APANAVICIUS, Andre; SANTANA, Pauliane; CARDENAS, Leticia; CARVALHO, Carlos Roberto Ribeiro de; CARUSO, Pedro; ALBUQUERQUE, Andre Luis Pereira de
- Volitional and non-volitional strength, synchrony and inspiratory force reserve in fibrosing interstitial lung disease at rest and during exercise(2015) SANTANA, Pauliane V.; CARDENAS, Leticia Z.; RAMOS, Ozires; FERREIRA, Jeferson G.; JAEGER, Thomas N.; TREVISAN, Patricia; MACCHIONE, Marcelo C.; CARVALHO, Carlos R. R.; ALBUQUERQUE, Andre L. P.; CARUSO, Pedro
- Respiratory work and its components during exercise in interstitial lung disease, COPD and controls(2015) FERREIRA, Jeferson George; CARDENAS, Leticia Zumpano; MACCHIONE, Marcelo; SANTANA, Pauliane; MALONI, Renan; PEREIRA, Mayra Caleffi; CARVALHO, Carlos Roberto R.; CARUSO, Pedro; ALBUQUERQUE, Andre
- Lung synchrony in different body positions in unilateral diaphragm paralysis(2018) PEREIRA, Mayra Caleffi; IAMONTI, Vinicius; FERREIRA, Jeferson; LIMA, Natalia; BADARO, Flavia; CARUSO, Pedro; CARVALHO, Carlos; ALBUQUERQUE, Andre
- Accuracy of Invasive and Noninvasive Parameters for Diagnosing Ventilatory Overassistance During Pressure Support Ventilation*(2018) PLETSCH-ASSUNCAO, Renata; PEREIRA, Mayra Caleffi; FERREIRA, Jeferson George; CARDENAS, Leticia Zumpano; ALBUQUERQUE, Andre Luis Pereira de; CARVALHO, Carlos Roberto Ribeiro de; CARUSO, PedroObjective: Evaluate the accuracy of criteria for diagnosing pressure overassistance during pressure support ventilation. Design: Prospective clinical study. Setting: Medical-surgical ICU. Patients: Adults under mechanical ventilation for 48 hours or more using pressure support ventilation and without any sedative for 6 hours or more. Overassistance was defined as the occurrence of work of breathing less than 0.3 J/L or 10% or more of ineffective inspiratory effort. Two alternative overassistance definitions were based on the occurrence of inspiratory esophageal pressure-time product of less than 50 cm H2O s/min or esophageal occlusion pressure of less than 1.5 cm H2O. Interventions: The pressure support was set to 20 cm H2O and decreased in 3-cm H2O steps down to 2 cm H2O. Measurements and Main Results: The following parameters were evaluated to diagnose overassistance: respiratory rate, tidal volume, minute ventilation, peripheral arterial oxygen saturation, rapid shallow breathing index, heart rate, mean arterial pressure, change in esophageal pressure during inspiration, and esophageal and airway occlusion pressure. In all definitions, the respiratory rate had the greatest accuracy for diagnosing overassistance (receiver operating characteristic area = 0.92; 0.91 and 0.76 for work of breathing, pressure-time product and esophageal occlusion pressure in definition, respectively) and always with a cutoff of 17 incursions per minute. In all definitions, a respiratory rate of less than or equal to 12 confirmed overassistance (100% specificity), whereas a respiratory rate of greater than or equal to 30 excluded overassistance (100% sensitivity). Conclusion: A respiratory rate of 17 breaths/min is the parameter with the greatest accuracy for diagnosing overassistance. Respiratory rates of less than or equal to 12 or greater than or equal to 30 are useful clinical references to confirm or exclude pressure support overassistance.
- Diaphragmatic ultrasound findings correlate with dyspnea, exercise tolerance, health-related quality of life and lung function in patients with fibrotic interstitial lung disease(2019) SANTANA, Pauliane Vieira; CARDENAS, Leticia Zumpano; ALBUQUERQUE, Andre Luis Pereira de; CARVALHO, Carlos Roberto Ribeiro de; CARUSO, PedroBackground Fibrotic interstitial lung disease (FILD) patients are typically dyspneic and exercise-intolerant with consequent impairment of health-related quality of life (HRQoL). Respiratory muscle dysfunction is among the underlying mechanisms of dyspnea and exercise intolerance in FILD but may be difficult to diagnose. Using ultrasound, we compared diaphragmatic mobility and thickening in FILD cases and healthy controls and correlated these findings with dyspnea, exercise tolerance, HRQoL and lung function. Methods We measured diaphragmatic mobility and thickness during quiet (QB) and deep breathing (DB) and calculated thickening fraction (TF) in 30 FILD cases and 30 healthy controls. We correlated FILD cases' diaphragmatic findings with dyspnea, exercise tolerance (six-minute walk test), lung function and HRQoL (St. George's Respiratory Questionnaire). Results Diaphragmatic mobility was similar between groups during QB but was lower in FILD cases during DB when compared to healthy controls (3.99 cm vs 7.02 cm; p < 0.01). FILD cases showed higher diaphragm thickness during QB but TF was lower in FILD when compared to healthy controls (70% vs 188%, p < 0.01). During DB, diaphragmatic mobility and thickness correlated with lung function, exercise tolerance and HRQoL, but inversely correlated with dyspnea. Most FILD cases (70%) presented reduced TF, and these patients had higher dyspnea and exercise desaturation, lower HRQoL and lung function. Conclusion Compared to healthy controls, FILD cases present with lower diaphragmatic mobility and thickening during DB that correlate to increased dyspnea, decreased exercise tolerance, worse HRQoL and worse lung function. FILD cases with reduced diaphragmatic thickening are more dyspneic and exercise-intolerant, have lower HRQoL and lung function.
conferenceObject Comparison of respiratory muscle recruitments between maximal voluntary contraction and strenuous exercise(2013) SANTANA, Pauliane; CARDENAS, Leticia; PLETSCH, Renata; FERREIRA, Jeferson; ORLANDIM, Luiz; ANDRE, Albuquerque; CARLOS, Carvalho; TREVIZAN, Patricia; MALONI, Renan; CARUSO, PedroconferenceObject Stability and agreement of micro-transducer esophageal catheter and air-filled balloon esophageal catheter: in vitro and in vivo study(2014) MALONI, Renan; ALBUQUERUUE, Andre; CARVALHO, Carlos; SALGE, Joao; CARDENAS, Leticia; FERREIRA, Jeferson; LAMONTI, Vinicius; ORLANDIN, Luiz; CARUSO, Pedro
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