VALERIA APARECIDA DA COSTA HONG
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conferenceObject Gender Differences of Aortic Wave Reflection and Influence of Menopause on Central Blood Pressure in Patients With Arterial Hypertension.(2017) COSTA-HONG, Valeria; MUELA, Henrique C.; MACEDO, Thiago A.; SALES, Allan R.; BORTOLOTTO, Luiz A.- Does Obstructive Sleep Apnea Influence Blood Pressure and Arterial Stiffness in Response to Antihypertensive Treatment?(2018) FATURETO-BORGES, Fernanda; JENNER, Raimundo; COSTA-HONG, Valeria; LOPES, Heno F.; TEIXEIRA, Sandra H.; MARUM, Elias; GIORGI, Dante A. M.; CONSOLIM-COLOMBO, Fernanda M.; BORTOLOTTO, Luiz A.; LORENZI-FILHO, Geraldo; KRIEGER, Eduardo M.; DRAGER, Luciano F.Untreated obstructive sleep apnea (OSA) is common in patients with hypertension and may impair blood pressure (BP) and target-organ damage responses to antihypertensive therapy. In this study, we recruited hypertensive patients who underwent treatment with a 30-day regimen of hydrochlorothiazide 25 mg plus enalapril (20 mg BID) or losartan (50 mg BID) and were assessed with a baseline clinical evaluation, polysomnography, 24-hour ambulatory BP monitoring, and carotid-femoral pulse wave velocity. All the examinations except for polysomnography were repeated at 6 and 18 months of follow-up. We studied 94 hypertensive patients (mean age, 55 +/- 9 years). The frequency of OSA was 55%. Compared with baseline, we did not observe significant differences between groups in 24-hour BP, daytime systolic and diastolic BPs, or night-time systolic BP at 6 and 18 months. The BP control rate at 24 hours (<130/80 mmHg) was similar between the groups (baseline, 42.3% versus 45.2%; 6 months, 46.9% versus 57.5%; 18 months, 66.7% versus 61.5%). However, patients with OSA had higher night-time diastolic BP decrease than did the non-OSA group (6 months, -4.9 +/- 11.8 versus -0.3 +/- 10.3 mmHg; 18 months, -6.7 +/- 11.1 versus -1.2 +/- 10.6 mmHg; P=0.027). There were no differences in the number and class of antihypertensive medications prescribed during follow-up. In terms of arterial stiffness, patients with OSA had higher pulse wave velocity than did patients without OSA at baseline (10.3 +/- 1.9 versus 9.2 +/- 1.7 m/s; P=0.024), but both groups had similar decreases in pulse wave velocity during follow-up. In conclusion, with combined antihypertensive treatment aimed at controlling BP, hypertensive patients with OSA had similar 24-hour BP and arterial stiffness to those without OSA.
conferenceObject Arterial Stiffness is Associated With Lower Performance on the Cognitive Tests at Different Domains in Hypertensive Patients.(2017) MUELA, Henrique; COSTA-HONG, Valeria; MACHADO, Michel F.; MORAES, Natalia C.; MEMORIA, Claudia M.; YASSUDA, Monica S.; SHU, Edson B.; MASSARO, Ayrton R.; NITRINI, Ricardo; MANSUR, Alfredo; BORTOLOTTO, LuizconferenceObject The Influence Of Religiosity On The Embracement Vs. Technology Based Distance Learning In Therapy Adherence In Patient Hypertensive(2016) GUERRA, Grazia M.; WEN, Chao L.; VIEIRA, Margarida; FISTAROL, Isabela; TSUNEMI, Miriam H.; GIORGI, Dante M.; MOTTA, Raquel A.; OLIVEIRA, Jefferson C.; HONG, Valeria; LOPES, Heno F.conferenceObject Increased Blood Pressure Variability and Baroreflex Impairment in Patients With End-stage Renal Disease Undergoing Hemodialysis(2013) SCAPINI, Katia B.; HONG, Valeria C.; FERREIRA, Janaina B.; SOUZA, Silvia B.; FERREIRA, Naomi V.; MORAES, Oscar A.; CONSOLIM-COLOMBO, Fernanda M.; LIMA, Jose J. de; MOSTARDA, Cristiano; IRIGOYEN, Maria C.conferenceObject Carvedilol Benefits in Hypertensive Cardiomyopathy(2016) DOMINGUEZ, Renata; COSTA-HONG, Valeria; CONSOLIM-COLOMBO, Fernanda; FERRETTI, Luan; BORTOLOTTO, Luiz; EGAN, Brent; LOPES, Heno F.