MARCOS ROBERTO DE MENEZES
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
Agora exibindo 1 - 6 de 6
- Percutaneous thermoablation of small renal masses (T1a) in surgical candidate patients: oncologic outcomes(2021) ZANGIACOMO, Renato N.; MARTINS, Guilherme L. P.; VIANA, Publio C. C.; HORVAT, Natally; ARAP, Marco A.; NAHAS, William C.; SROUGI, Miguel; CERRI, Giovanni G.; MENEZES, Marcos R.Objective To evaluate the local tumour progression-free survival (LTPFS), metastasis-free survival (MFS), cancer-specific survival (CSS) and overall survival (OS) of healthy surgical candidates who underwent percutaneous thermoablation (TA) as a first-line therapy for small renal masses (T1a). Methods The institutional review board approved this bi-institutional retrospective study of 85 consecutive surgical candidates with 97 biopsy-proven malignant renal masses (T1a) treated with percutaneous TA from 2008 to 2016. The LTPFS, MFS, CSS and OS rates were calculated using the Kaplan-Meier method. Descriptive analysis was also performed. Results The median tumour size was 2.3 cm (range, 0.7-3.9 cm). The minimal and mean follow-up periods were 24 and 56 months, respectively. Local recurrence was detected in four patients (4.7%) at 8.5, 13.8, 58.0 and 64.0 months of follow-up and retreated successfully with percutaneous TA. No patient developed metastatic renal cell carcinoma, and none died due to renal oncologic complications. One patient died of heart attack. The 5-year LTPFS, OS, MFS and CSS rates were 93.0%, 98.4%, 100% and 100%, respectively. Only two patients (2.3%) had major complications (Clavien-Dindo grade > II), including ureteropelvic junction stenosis and urinary obstruction due to ureteral blood clots. Conclusions Our study demonstrates that percutaneous TA is a feasible and effective first-line therapy for healthy surgical candidates with small renal masses (T1a). The 5-year LTPFS, OS, CSS and MFS rates were 93.0%, 98.4%, 100% and 100%, respectively, with a major complication rate of only 2.3%.
- Radiofrequency ablation for treatment of hypersplenism: A feasible therapeutic option(2015) MARTINS, Guilherme Lopes P.; BERNARDES, Joao Paulo G.; ROVELLA, Marcello S.; ANDRADE, Raphael G.; VIANA, Publio Cesar C.; HERMAN, Paulo; CERRI, Giovanni Guido; MENEZES, Marcos RobertoWe present a case of a patient with hypersplenism secondary to portal hypertension due to hepato-splenic schistosomiasis, which was accompanied by severe and refractory thrombocytopenia. We performed spleen ablation and measured the total spleen and ablated volumes with contrast-enhanced computed tomography and volumetry. No major complications occurred, thrombocytopenia was resolved, and platelet levels remained stable, which allowed for early treatment of the patient's underlying disease. Previous work has shown that splenic radiofrequency ablation is an attractive alternative treatment for hypersplenism induced by liver cirrhosis. We aimed to contribute to the currently sparse literature evaluating the role of radiofrequency ablation (RFA) in the management of hypersplenism. We conclude that splenic RFA appears to be a viable and promising option for the treatment of hypersplenism.
- MAGNETIC RESONANCE-GUIDED HIGH-INTENSITY FOCUSED ULTRASOUND ABLATION OF OSTEOID OSTEOMA: A CASE SERIES REPORT(2016) ROVELLA, Marcello S.; MARTINS, Guilherme L. P.; CAVALCANTI, Conrado F. A.; BOR-SENG-SHU, Edson; CAMARGO, Olavo P.; CERRI, Giovanni G.; MENEZES, Marcos R.Osteoid osteoma is painful benign tumor. The aim of this study was to report our initial experience using magnetic resonance-guided focused ultrasound to treat osteoid osteomas. This retrospective single-center study included four patients treated with magnetic resonance-guided focused ultrasound. They presented with severe pain with reduced quality of life and a poor response to clinical treatment. The pre- and post-treatment evaluation comprised computed tomography and magnetic resonance imaging and focused on quality of life and the impact of pain on daily activities. After treatment, three patients had complete pain resolution with no recurrence. One patient had a recurrence of symptoms after 2 wk and underwent a new successful treatment with increased energy levels. On average, 13 sonications were administered (8-18 sonications/treatment) with an average energy of 2,003 J (range: 1,063-3,522 J). Magnetic resonance-guided focused ultrasound appears to be a feasible, tolerable and effective treatment in selected patients with osteoid osteomas. (E-mail: marcos.menezes@hc.fm.usp.br) (C) 2016World Federation for Ultrasound in Medicine & Biology.
- Local-Regional Treatment of Hepatocellular Carcinoma: A Primer for Radiologists(2022) HORVAT, Natally; OLIVEIRA, Ana I. De; OLIVEIRA, Brunna Clemente De; ARAUJO-FILHO, Jose A. B.; HOMSI, Maria El; ELSAKKA, Ahmed; BAJWA, Raazi; MARTINS, Guilherme L. P.; ELSAYES, Khaled M.; MENEZES, Marcos R.The treatment planning for patients with hepatocellular carcinoma (HCC) relies predominantly on tumor burden, clinical perfor-mance, and liver function test results. Curative treatments such as resection, liver transplantation, and ablative therapies of small lesions should be considered for all patients with HCC. However, many patients are ineligible for these treatments owing to advanced disease stage and comorbidities. Despite efforts to increase screen-ing, early-stage HCC remains difficult to diagnose, which decreases the possibility of curative therapies. In this context, local-regional treatment of HCC is accepted as a form of curative therapy in selected patients with early-stage disease, as a therapeutic option in patients who are not eligible to undergo curative therapies, as a downstaging approach to decrease tumor size toward meeting the criteria for liver transplantation, and as a bridging therapy to avoid tumor growth while the patient is on the waiting list for liver trans-plantation. The authors review the indications, types, mechanism of action, and possible complications of local-regional treatment, as well as the expected postprocedural imaging features of HCC. Furthermore, they discuss the role of imaging in pre-and post-procedural settings, provide guidance on how to assess treatment response, and review the current limitations of imaging assessment. Finally, the authors summarize the potential future directions with imaging tools that may add value to contemporary practice at re-sponse assessment and imaging biomarkers for patient selection, treatment response, and prognosis.
- Microwave ablation: initial experience in Brazil(2020) ROVELLA, Marcello Silveira; FIORE, Lucas; ALLEGRO FILHO, Alfredo Enzo; MARTINS, Guilherme Lopes Pinheiro; MENEZES, Marcos Roberto
- Systemic Air Embolism after Percutaneous Lung Biopsy: A Manageable Complication(2017) FIORE, Lucas; FRENK, Nathan Elie; MARTINS, Guilherme Lopes Pinheiro; VIANA, Publio Cesar Cavalcante; MENEZES, Marcos Roberto deCT-guided percutaneous biopsy is a resourceful and widely used tool to evaluate pulmonary nodules that frequently avoids costly and unnecessary surgeries. Severe complications occur in less than 1% of cases and include gas embolism, which is rarely documented. We report a case of gas embolism after transthoracic biopsies and discuss the pathophysiology and the benefits of early diagnosis and proper management.