GABRIEL ANDREUCCETTI
Projetos de Pesquisa
Unidades Organizacionais
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense, Hospital das Clínicas, Faculdade de Medicina
12 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 12
- A review of emergency room studies on alcohol and injuries conducted in Latin America and the Caribbean region(2012) ANDREUCCETTI, Gabriel; CARVALHO, Heraclito B.; KORCHA, Rachael; YE, Yu; BOND, Jason; CHERPITEL, Cheryl J.Issues. Alcohol-attributable burden of injury is one of the most serious public health problems in Latin America and the Caribbean region (LAC). Although knowledge on alcohol's involvement in injuries has progressed along with the implementation of evidenced-based alcohol policies in developed countries, this was not true for the most part of LAC countries for which reducing alcohol-related injuries is an urgent necessity. Approach. A systematic review was performed in order to identify the most up-to-date information on alcohol and injuries derived from emergency room (ER) studies conducted in LAC. Key Findings. Findings corroborate that alcohol has a high prevalence among injured patients in the ER setting in LAC, with violence-related injuries showing an increased association with alcohol use compared to unintentional injuries. However, a large number of studies did not include all types of injury and the measurement of injury risk associated with alcohol consumption. The amount of alcohol consumed in the event and hazardous drinking patterns seem to be strongly associated with injury occurrence, as well as drinking in public spaces, but a paucity of data relating to social-contextual factors limits the interpretation of the heterogeneity in the magnitude of the association of alcohol and injuries found across studies. Conclusions. There is a lack of ER studies able to support strategies to reduce alcohol-related injuries in a region where effective alcohol policies are scant. Future research should focus on understanding how drinking influenced by local contexts and drinking behaviours may affect the risk of injury within each LAC country.[Andreuccetti G, Carvalho HB, Korcha R, Ye Y, Bond J, Cherpitel CJ. A review of emergency room studies on alcohol and injuries conducted in Latin America and the Caribbean region. Drug Alcohol Rev 2012;31:737746]
- Alcohol use among fatally injured victims in SAo Paulo, Brazil: bridging the gap between research and health services in developing countries(2017) ANDREUCCETTI, Gabriel; LEYTON, Vilma; LEMOS, Nikolas P.; MIZIARA, Ivan Dieb; YE, Yu; TAKITANE, Juliana; MUNOZ, Daniel Romero; REINGOLD, Arthur L.; CHERPITEL, Cheryl J.; CARVALHO, Heraclito Barbosa deBackground and aimsMost studies reporting alcohol use among fatally injured victims are subject to bias, particularly those related to sample selection and to absence of injury context data. We developed a research method to estimate the prevalence of alcohol consumption and test correlates of alcohol use prior to fatal injuries. Design, Setting and ParticipantsCross-sectional study based on a probability sample of fatally injured adult victims (n=365) autopsied in SAo Paulo, Brazil. Victims were sampled within systematically selected 8-hour sampling blocks, generating a representative sample of fatal injuries occurring during all hours of the day for each day of the week between June 2014 and December 2015. MeasurementsThe presence of alcohol and blood alcohol concentration (BAC) were the primary outcomes evaluated according to victims' socio-demographic, injury context data (type, day, time and injury place) and criminal history characteristics. FindingsAlcohol was detected in 30.1% [95% confidence interval (CI)=25.6-35.1)] of the victims, with a mean blood alcohol level (BAC) level of 0.11%w/v (95% CI=0.09-0.13) among alcohol-positive cases. Black and mixed race victims presented a higher mean BAC than white victims (P=0.03). Fewer than one in every six suicides tested positive for alcohol, while almost half of traffic-related casualties were alcohol-positive. Having suffered traffic-related injuries, particularly those involving vehicle crashes, and injuries occurring during weekends and at night were associated significantly with alcohol use before injury (P<0.05). ConclusionsNearly one-third of fatal injuries in SAo Paulo between June 2014 and December 2015 were alcohol-related, with traffic accidents showing a greater association with alcohol use than other injuries. The sampling methodology tested here, including the possibility of adding injury context data to improve population-based estimates of alcohol use before fatal injury, appears to be a reliable and lower-cost strategy for avoiding biases common in death investigations.
- Alcohol Use and Injury Severity Among Emergency Department Patients in Six Countries(2013) KORCHA, Rachael A.; CHERPITEL, Cheryl J.; YE, Yu; BOND, Jason; ANDREUCCETTI, Gabriel; BORGES, Guilherme; BAZARGAN-HEJAZI, ShahrzadThis study examines the individual and sociocultural factors related to severity of injury among emergency department (ED) patients across six countries (United States, Canada, Mexico, Australia, Spain, and Italy). Secondary analysis of existing data using probability samples of injured patients from 15 studies (N = 9,599) were analyzed for severity of injury as measured by arrival by ambulance and admission to the hospital, using logistic regression models and multilevel hierarchical linear models. Patients drinking greater quantities of alcohol before the injury were more likely to have arrived to the ED by ambulance or admitted to the hospital after the injury event. Country-level detrimental drinking pattern explained some of the study variation for patients arriving by ambulance but not for patients admitted to the ED. Findings support a relationship between acute alcohol consumption to injury severity; however, further examination of the clinical implications related to triage, patient evaluation, and intervention for alcohol-related problems is merited.
- Reducing the legal blood alcohol concentration limit for driving in developing countries: a time for change? Results and implications derived from a time-series analysis (2001-10) conducted in Brazil (vol 106, pg 2124, 2011)(2012) ANDREUCCETTI, Gabriel; CARVALHO, Heraclito B.; CHERPITEL, Cheryl J.; YE, Yu; PONCE, Julio C.; KAHN, Tulio; LEYTON, Vilma
- THE CALL FOR EVIDENCE-BASED DRINK AND DRIVING POLICIES IN BRAZIL(2012) ANDREUCCETTI, Gabriel; CARVALHO, Heraclito Barbosa De; CHERPITEL, Cheryl J.; LEYTON, Vilma
- Introducing a new research method for evaluating alcohol and other drug use among fatally injured victims in Latin America(2017) ANDREUCCETTI, Gabriel; LEYTON, Vilma; MIZIARA, Ivan Dieb; LEMOS, Nikolas P.; MUNOZ, Daniel Romero; CHERPITEL, Cheryl J.; CARVALHO, Heraclito Barbosa
- Development of the International Alcohol Policy and Injury Index(2018) KORCHA, Rachael A.; WITBRODT, Jane; CHERPITEL, Cheryl J.; YE, Yu; ANDREUCCETTI, Gabriel; KANG, Jaewook; MONTEIRO, MaristelaObjective. To develop a new index to measure the effectiveness of alcohol control policies on selected indicators of alcohol-related injuries. Methods. We used the World Health Organization Global Information System on Alcohol and Health (GISAH) for cross-sectional data from 156 countries for this analysis. Five policy domains were selected: physical availability, drinking context, pricing, advertising, and vehicular. Injury mortality and alcohol-attributable fractions (AAFs) for vehicular deaths were also used for the same countries. We created a new composite indicator, the International Alcohol Policy Injury Index (IAPII), in order to assess the association between policy and deaths due to alcohol-related injury. Results. After we controlled for per-capita alcohol consumption, we found that injury deaths and AAF deaths were inversely associated with four of the five policy domains. The domains were weighted according to effectiveness and used to construct the IAPII, which produced acceptable sensitivity and specificity. Regression results, controlling for consumption, demonstrated that the IAPII was significantly associated with AAF vehicular injury death for males, AAF vehicular injury death for females, and overall injury death at p < 0.01. Conclusions. Our findings support the IAPII as a reliable indicator of the relationship between alcohol policies and injury deaths: the stronger the policy, the less the likelihood of both overall and vehicular injury death. Future work should test the effectiveness of the IAPII in reducing alcohol-related injury morbidity, which accounts for a larger share of the global burden of disease than alcohol-related injury mortality does.
- RETHINKING THE DEBATE ON DRINKING AND DRIVING LAWS IN SAO PAULO: RESPONSE TO THE LETTER BY VOLPE & FANTONI(2015) ANDREUCCETTI, Gabriel; CARVALHO, Heraclito Barbosa de; CHERPITEL, Cheryl J.; YE, Yu; LEYTON, Vilma
- Alcohol use among fatally injured victims in Sao Paulo, Brazil: bridging the gap between research and health services in developing countries (vol 112, pg 596, 2017)(2017) ANDREUCCETTI, Gabriel; LEYTON, Vilma; LEMOS, Nikolas P.; MIZIARA, Ivan Dieb; YE, Yu; TAKITANE, Juliana; MUNOZ, Daniel Romero; REINGOLD, Arthur L.; CHERPITEL, Cheryl J.; CARVALHO, Heraclito Barbosa de
- Reducing the legal blood alcohol concentration limit for driving in developing countries: a time for change? Results and implications derived from a time-series analysis (2001-10) conducted in Brazil(2011) ANDREUCCETTI, Gabriel; CARVALHO, Heraclito B.; CHERPITEL, Cheryl J.; YE, Yu; PONCE, Julio C.; KAHN, Tulio; LEYTON, VilmaAims In Brazil, a new lawintroduced in 2008 has lowered the blood alcohol concentration limit for drivers from 0.06 to 0.02, but the effectiveness in reducing traffic accidents remains uncertain. This study evaluated the effects of this enactment on road traffic injuries and fatalities. Design Time-series analysis using autoregressive integrated moving average (ARIMA) modelling. Setting State and capital of Sao Paulo, Brazil. Participants A total of 1 471 087 non-fatal and 51 561 fatal road traffic accident cases in both regions. Measurements Monthly rates of traffic injuries and fatalities per 100 000 inhabitants from January 2001 to June 2010. Findings The new traffic law was responsible for significant reductions in traffic injury and fatality rates in both localities (P < 0.05). A stronger effect was observed for traffic fatality (-7.2 and -16.0% in the average monthly rate in the State and capital, respectively) compared to traffic injury rates (-1.8 and -2.3% in the State and capital, respectively). Conclusions Lowering the blood alcohol concentration limit in Brazil had a greater impact on traffic fatalities than injuries, with a higher effect in the capital, where presumably the police enforcement was enhanced.