ERASMO BARBANTE CASELLA
Projetos de Pesquisa
Unidades Organizacionais
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina - Médico
7 resultados
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- Attention deficit hyperactivity disorder and restless leg syndrome across the lifespan: A systematic review and meta-analysis(2023) MIGUEIS, D. P.; LOPES, M. C.; CASELLA, E.; SOARES, P. V.; SOSTER, L.; SPRUYT, K.This systematic review aims to assess the association between attention deficit hyperactivity disorder (ADHD) and restless legs syndrome (RLS) in accordance with the Preferred Reporting Items for Sys-tematic Reviews and Meta-Analyses (PRISMA) guidelines. Databases were searched for original articles that reported prevalence data on ADHD and RLS until January 24th, 2023. Two independent reviewers evaluated the quality of the articles using the National Institutes of Health assessment tool. Among the 208 articles identified between 1996 and 2022, 29 were included. In large general population studies, 2.6-15.3% of participants met the RLS criteria, of which 3.2-17.4% presented with ADHD. In the ADHD group, RLS symptoms ranged from 11 to 42.9% in children and 20-33.0% in adults. This suggests a strong co-occurrence between RLS and ADHD. A common characteristic of these conditions is sleep fragmen-tation, as discussed in the reviewed papers. Although large-scale studies with comparable diagnostic criteria across the lifespan are required, our findings may advocate a possible common physiological pathway, including sleep fragmentation and dopaminergic system impairment.(c) 2023 Elsevier Ltd. All rights reserved.
- Attention deficit disorder/hyperactivity: a scientific overview(2012) POLANCZYK, Guilherme V.; CASELLA, Erasmo Barbante; MIGUEL, Euripedes Constantino; REED, Umbertina Conti
- Validation of the Expression and Emotion Scale for Children with attention deficit hyperactivity disorder into Brazilian Portuguese(2017) SIMON, Margarete Andreozzi Vaz Pereira; REED, Umbertina Conti; VAUGHAN, Brigette; SIMON, Valdecir Antonio; CASELLA, Erasmo BarbanteObjective: To validate the parent-rated Expression and Emotion Scale for Children (EESC) for patients with attention-deficit/ hyperactivity disorder (ADHD). Methods: The EESC was applied to parents of children with and without ADHD. The children were divided into age groups: Group A, between six and eight years old; Group B, between nine and 11 years old; and Group C, between 12 and 15 years old. The validation was carried out according to the steps proposed by Guillemin et al. For the statistical calculation, Cronbach's alpha, Pearson's correlation, the ICC and ROC curve were used. Results: The statistical tests showed satisfactory coefficients: Cronbach's alpha = 0.76; Pearson's correlation r = 0.91 with CI 95%; replicability ICC = 0.66; sensitivity 0.75; specificity 0.67; accuracy 71%. Conclusion: According to psychometric data on internal and external consistency (reliability, reproducibility), sensitivity, and specificity, the parent-rated EESC for ADHD is useful in assessing emotional expression.
article 19 Citação(ões) na Scopus Quality of life and psychomotor profile of children with attention deficit hyperactivity disorder (ADHD)(2011) GOULARDINS, Juliana Barbosa; MARQUES, Juliana Cristina Fernandes Bilhar; CASELLA, Erasmo BarbanteThe knowledge of psychomotor development of children with attention deficit hyperactivity disorder (ADHD) may help in defining therapeutic approaches in order to minimize losses in their quality of life. The study objectives were to evaluate the quality of life and psychomotor profile of children with ADHD and check your correlation. Fourteen children, from seven to ten years, with ADHD combined type were evaluate using the scales PedsQL (TM) and Motor Development Scale. Results showed adverse effects of ADHD on quality of life and a deficit in motor skills. Nine participants (64.2%) were classified in motor development as ""Normal Medium"", followed by the classification ""Normal Low"" in four (28.5%) and ""Low"" in one subject (7.1%). We observed a positive correlation between quality of life and psychomotor development of children with ADHD, especially in areas: fine motor and spatial organization with social and psychosocial aspects, gross motor control with the emotional and temporal organization with the emotional, psychosocial and overall quality of life.- Motor profile of children with attention deficit hyperactivity disorder, combined type(2013) GOULARDINS, Juliana B.; MARQUES, Juliana C. Bilhar; CASELLA, Erasmo B.; NASCIMENTO, Roseane O.; OLIVEIRA, Jorge A.Objectives: The aim of this study was to assess the motor profile of children with attention deficit hyperactivity disorder (ADHD), combined type. Method: The case group consisted of 34 treatment-naive, male patients, aged 7-11 years, who had been diagnosed with ADHD, combined type, without comorbidities (except oppositional defiant disorder). The control group was composed of 32 age- and gender-matched, typically developing children. The evaluation was made using the Motor Development Scale, which assessed global and fine motricity, balance, body scheme, and spatial and temporal organization. Results: The results showed that the motor quotients in all areas studied were lower in the ADHD group than in the control group, although in most cases they represent normal values relative to the scale (53% were classified as having ""normal medium"" motor development, 29% ""normal low"", 9% ""very low"", 6% ""normal high"" and 3% as ""lower""). Statistically significant differences between groups were observed in general motor age, general motor quotient, balance, spatial organization, and fine and global motricity. Conclusion: Difficulties in motor performance were observed in the children with ADHD, combined type. The identification of such deficits may assist in the design of therapeutic protocols for the treatment of children with this type of ADHD.
- Comparison of child self-reports and parent proxy-reports on quality of life of children with attention deficit hyperactivity disorder(2013) MARQUES, Juliana C. B.; OLIVEIRA, Jorge A.; GOULARDINS, Juliana B.; NASCIMENTO, Roseane O.; LIMA, Allana M. V.; CASELLA, Erasmo B.Background: Attention deficit hyperactivity disorder (ADHD) is a neurobiological condition that affects 3%-7% of the pediatric population and significantly compromises the quality of life (QoL) of these individuals. The aim of the current study was to compare child self-reports and parent proxy reports on the QoL of children with ADHD. Methods: Forty-five children with ADHD, combined type, aged 8-12 years without comorbidities, were compared with 43 typically developing children. PedsQL (TM) 4.0 (Pediatric QoL Inventory (TM)) Generic Core Scales (physical, emotional, social, and school functioning) were completed by families and children self-reporting their health-related QoL. Results: Children with ADHD reported themselves significantly lowered their PedsQL (TM) scores on all dimensions in comparison to typically developing children. Statistically significant differences were observed in social functioning (p = 0.010), school functioning (p < 0.001), psychosocial health (p < 0.001), and total score (p = 0.002). The physical functioning and emotional functioning dimensions did not differ significantly between groups, with p = 0.841 and p = 0.070, respectively. Parents of children with ADHD also reported lower PedsQL (TM) scores, with statistically significant differences in all dimensions. The relationship between child self-reports and parent proxy reports indicated that there is greater agreement among children with ADHD, except for the school functioning. Conclusions: This suggests that children with the disorder and their parents have a perception of the functional limitations the disorder brings. It is therefore important to undertake studies to verify the QoL in children with ADHD that aim to provide and measure the scope of the well-being of these children.
- Associations between Attention-Deficit Hyperactivity Disorder (ADHD) Treatment and Patient Nutritional Status and Height(2018) GRANATO, Mariana F.; FERRARO, Alexandre A.; LELLIS, Denise M.; CASELLA, Erasmo B.Attention-deficit hyperactivity disorder (ADHD) has been found to co-occur frequently with obesity, although the reasons for this association are unknown. The aim of this study was to compare the nutritional profile of a Brazilian cohort of ADHD patients with that of the general population and to analyze the association between ADHD drug treatment (with methylphenidate), nutritional status, and height of these individuals. In the first phase of the study, we designed the nutritional and height profile of 93 ADHD patients (5.1 to 13.8 years old) and compared it to a control group. In the second phase, we analyzed the association of the use of methylphenidate with nutritional status and height. The results showed that the prevalence of overweight/obesity was statistically higher in the cohort of ADHD patients compared to controls (40.9% vs. 34.7%; P < 0.05). After treating ADHD patients with methylphenidate, a statistically significant decrease in the BMI z-score was observed (0.695 vs. 0.305; P < 0.01). On the other hand, no significant impact on height was detected after treatment (0.189 vs. 0.248; P = 0.298). In conclusion, the results suggest that the use of methylphenidate in patients who have ADHD and obesity is relevant not only for controlling ADHD symptoms but also for improving the nutritional status of these individuals. Moreover, the treatment did not affect the patients' height.