DALTON MARQUES CHAVES
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
4 resultados
Resultados de Busca
Agora exibindo 1 - 4 de 4
- Comprehensive Analysis of Adverse Events Associated with Gastric Peroral Endoscopic Myotomy: An International Multicenter Study(2021) ICHKHANIAN, Y.; VOSOUGHI, K.; MEYBODI, M. Aghaie; JACQUES, J.; SETHI, A.; PATEL, A. A.; AADAM, A. A.; TRIGGS, J. R.; BAPAYE, A.; DORWAT, S.; BENIAS, P.; CHAVES, D. M.; BARRET, M.; LAW, R. J.; BROWERS, N.; PIOCHE, M.; V, P. Draganov; KOTZEV, A.; ESTREMERA, F.; ALBENIZ, E.; UJIKI, M. B.; CALLAHAN, Z. M.; ITANI, I. M.; BREWER, O. G.; KHASHAB, M. A.Background Gastric peroral endoscopic myotomy (G-POEM) has emerged as an effective management approach for patients with refractory gastroparesis. This study aims to comprehensively study the safety of G-POEM and describe the predictive factors of adverse events (AEs) occurrence. Methods This study is a retrospective study involving 13 tertiary care centers (7 USA, 1 South America, 4 Europe, and 1 Asia). Patients who underwent G-POEM for refractory gastroparesis were included. Cases were identified by the occurrence of AEs. For each case, two controls were randomly selected and matched for age (+/- 10 years), gender, and etiology of gastroparesis. Results A total of 216 patients underwent G-POEM for gastroparesis. Overall, 31 (14%) AEs were encountered [mild 24 (77%), moderate 5 (16%), and severe 2 (6%)] during the duration of the study. The most common AE was abdominal pain (n = 16), followed by mucosotomy (n = 5) and capnoperitoneum (n = 4), and AEs were most commonly identified within the first 48-h post-procedure 18 (58%). The risk of adverse event occurrence was significantly higher for endoscopists with experience of < 20 G-POEM procedures (OR 3.03 [1.03-8.94], p < 0.05). Conclusion G-POEM seems to be a safe intervention for refractory gastroparesis. AEs are most commonly mild and managed conservatively. Longitudinal mucosal incision, use of hook knife, use of clips for mucosal closure and endoscopist's experience with > 20 G-POEM procedures is significantly associated with decreased incidence of AEs.
- Comprehensive analysis of adverse events associated with gastric peroral endoscopic myotomy: an international multicenter study (vol 10, pg 513, 2020)(2021) ICHKHANIAN, Y.; VOSOUGHI, K.; MEYBODI, M. Aghaie; JACQUES, J.; SETHI, A.; PATEL, A. A.; AADAM, A. A.; TRIGGS, J. R.; BAPAYE, A.; DORWAT, S.; BENIAS, P.; CHAVES, D. M.; BARRET, M.; LAW, R. J.; BROWERS, N.; PIOCHE, M.; DRAGANOV, P. V.; KOTZEV, A.; ESTREMERA, F.; ALBENIZ, E.; UJIKI, M. B.; CALLAHAN, Z. M.; ITANI, M. I.; BREWER, O. G.; KHASHAB, M. A.
- GASTRIC PERORAL ENDOSCOPIC MYOTOMY (G-POEM) FOR THE TREATMENT OF REFRACTORY GASTROPARESIS: RESULTS FROM THE FIRST INTERNATIONAL PROSPECTIVE TRIAL(2019) VOSOUGHI, Kia; ICHKHANIAN, Yervant; BENIAS, Petros C.; MILLER, Larry S.; AADAM, A. Aziz; TRIGGS, Joseph; LAW, Ryan; CHAVES, Dalton; PONTE, Alberto M. da; DRAGANOV, Peter V.; KOTZEV, Andrey I.; HALABI, Maan El; SANAEI, Omid; GUTIERREZ, Olaya I. Brewer; PANDOLFINO, John E.; KALLOO, Anthony N.; KHASHAB, Mouen A.
- COMPREHENSIVE CASE-MATCHED STUDY ON ADVERSE EVENTS ASSOCIATED WITH GASTRIC PER ORAL ENDOSCOPIC MYOTOMY(2019) ICHKHANIAN, Yervant; VOSOUGHI, Kia; MEYBODI, Mohamad Aghaie; JACQUES, Jeremie; SETHI, Amrita; PATEL, Anish; AADAM, A. Aziz; TRIGGS, Joseph; BENIAS, Petros C.; CHAVES, Dalton; BARRET, Maximilien; LAW, Ryan; BOWERS, Nicole; PIOCHE, Mathieu; DRAGANOV, Peter V.; KOTZEV, Andrey I.; ALBENIZ, Eduardo; ESTREMERA, Fermin; UJIKI, Michael; CALLAHAN, Zachary M.; BAPAYE, Amol; DORWAT, Shivangi; GUTIERREZ, Olaya I. Brewer; KHASHAB, Mouen A.