GISELE RODRIGUES GOUVEIA
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Psiquiatria, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
LIM/21 - Laboratório de Neuroimagem em Psiquiatria, Hospital das Clínicas, Faculdade de Medicina
8 resultados
Resultados de Busca
Agora exibindo 1 - 8 de 8
conferenceObject THE DOWREGULATION EXPRESSION OF PROLINE OXIDASE GENE IMBALANCE GLUTAMATE IN BRAINS OF THE SUBJECTS WITH OBSESSIVE COMPULSIVE DISORDER A POST MORTEM STUDY(2017) OLIVEIRA, Katia de; LISBOA, Bianca Cristina Garcia; CARREIRA, Luzia Lima; GOUVEIA, Gisele Rodrigues; MORETTO, Ariane Cristine; NEVES, Ricardo de Caires; PASQUA-LUCCI, Carlos Augusto; GRINBERG, Lea Tenenholz; JACOB-FILHO, Wilson; LAFER, Beny; MIGUEL, Euripedes Constantino; SHAVITT, Roseli Gedanke; HOEXTER, Marcelo Queiroz; PEREIRA, Carlos Alberto de Bragranca; BRENTANI, HelenaconferenceObject GAD1 POLYMORPHISMS ARE ASSOCIATED WITH GLUTAMATERGIC ACTIVITY IN THE ANTERIOR CINGULATE IN BIPOLAR I DISORDER(2017) SOEIRO-DE-SOUZA, Marcio; MACHADO-VIEIRA, Rodrigo; MORENO, Ricardo; CHILE, Thais; GOUVEIA, Gisele; PASTORELLO, Bruno; LEITE, Claudia; HENNING, Anke; OTADUY, Maria Concepcion; VALLADA, Homero- IDENTIFICATION OF O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE (OGT) EXPRESSION IN HUMAN PLACENTAS AS A POTENTIAL BIOMARKER OF PRENATAL STRESS EXPOSURE(2022) CAMILO, Caroline; VIEIRA, Luana Martos; TORREZAN, Arleti Caramori; SOUSA, Antonia Beatriz; GOUVEIA, Gisele Rodrigues; EUCLYDES, Veronica Luiza Vale; SILVA, Aloisio Souza Felipe da; BRENTANI, Alexandra; BRENTANI, Helena
- Genome-wide DNA methylation profile in the peripheral blood of cocaine and crack dependents(2019) CAMILO, Caroline; MASCHIETTO, Mariana; VIEIRA, Henrique C.; TAHIRA, Ana C.; GOUVEIA, Gisele R.; SANTOS, Ana C. Feio dos; NEGRAO, Andre B.; RIBEIRO, Marcelo; LARANJEIRA, Ronaldo; VALLADA, Homero; BRENTANI, HelenaObjective: Cocaine use disorders (CUDs) represent a major public health problem in many countries. To better understand the interaction between the environmental modulations and phenotype, the aim of the present study was to investigate the DNA methylation pattern of CUD patients, who had concomitant cocaine and crack dependence, and healthy controls. Methods: We studied DNA methylation profiles in the peripheral blood of 23 CUD patients and 24 healthy control subjects using the Illumina Infinium HumanMethylation450 BeadChip arrays. Results: Comparison between CUD patients and controls revealed 186 differentially methylated positions (DMPs; adjusted p-value [adjP] < 10(-5)) related to 152 genes, with a subset of CpGs confirmed by pyrosequencing. DNA methylation patterns discriminated CUD patients and control groups. A gene network approach showed that the EHMT1, EHMT2, MAPK1, MAPK3, MAP2K1, and HDAC5 genes, which are involved in transcription and chromatin regulation cellular signaling pathways, were also associated with cocaine dependence. Conclusion: The investigation of DNA methylation patterns may contribute to a better understanding of the biological mechanisms involved in CUD.
- DNA METHYLATION OF STRESS-RESPONSE HPA RELATED GENES COULD BE PROGRAMMED BY PRENATAL STRESS EXPOSURES(2022) GOUVEIA, Gisele; EUCLYDES, Veronica; BRAGA, Caio; WILEY, Kyle; CAMILO, Caroline; POLANCZYK, Guilherme; BRENTANI, Helena
- Associations between maternal cortisol during pregnancy, methylation of glucocorticoid regulatory genes, and infant stress physiology at 12 months(2019) WILEY, Kyle Steven; CAMILO, Caroline; GOUVEIA, Gisele; EUCLYDES, Veronica; POLANCZYK, Guilherme; MIGUEL, Euripedes; BRENTANI, Helena
conferenceObject ASSOCIATION OF LITHIUM RESPONSE TO TELOMERE LENGTH IN BIPOLAR DISORDER IN A BRAZILIAN COHORT(2017) MICHELON, Leandro; MARTINEZ, Daniela; CHILE, Thais; GOUVEIA, Gisele; CAMILO, Caroline; SCHALLING, Martin; VALLADA, Homero- CHARACTERIZATION OF DNA METHYLATION CHANGES IN THE PERIPHERAL BLOOD OF COCAINE AND CRACK DEPENDENTS(2019) CAMILO, Caroline; MASCHIETTO, Mariana; VIEIRA, Henrique C.; TAHIRA, Ana Carolina; GOUVEIA, Gisele Rodrigues; NEGRAO, Andre Brooking; RIBEIRO, Marcelo; LARANJEIRA, Ronaldo; BRENTANI, Helena; VALLADA, Homero