ISAAC DE FARIA SOARES RODRIGUES
Projetos de Pesquisa
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LIM/61 - Laboratório de Pesquisa em Cirurgia Torácica, Hospital das Clínicas, Faculdade de Medicina
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bookPart Afecções congênitas de traqueia e brônquios(2021) MINAMOTO, Hélio; RODRIGUES, Isaac de Faria Soares; CARDOSO, Paulo Francisco Guerreiro- Posterior laryngofissure using a surgical contact diode laser: an experimental feasibility study(2019) MENEZES, Arteiro Queiroz; CARDOSO, Paulo Francisco Guerreiro; NAGAO, Christopher Kengo; MINAMOTO, Helio; BIBAS, Benoit Jacques; RODRIGUES, Isaac de Faria Soares; OTOCH, Jose Pinhata; DOLHNIKOFF, Marisa; CANZIAN, Mauro; MANCINI, Marilia Wellichan; PEGO-FERNANDES, Paulo ManuelTo evaluate the feasibility of a 980-nm contact diode laser (CDL) as a method for creating a posterior laryngofissure in live pigs. Twenty-eight Landrace pigs (15-20 kg) were anesthetized, intubated, ventilated, and submitted to a cervical tracheostomy. An anterior and posterior midline longitudinal laryngofissure incision was created according to randomization-control (n = 4), posterior laryngofissure with a scalpel blade; electrocautery (n = 12), posterior laryngofissure by electrocautery (10, 15, 20, 25 W powers); CDL (n = 12), posterior laryngofissure by the CDL (10, 15, 20, 25 W peak powers in pulsed mode). Larynx and proximal trachea were excised, prepared for histopathology, and digital morphometric analysis. Measurements in and within each group were analyzed (Kruskal-Wallis and Dunn test) with a level of significance of p < 0.05. Incision width was not different between the groups, as well as in the powers used in CDL (p = 0.161) and electrocautery group (p = 0.319). The depth of the incisions was smaller in the Laser group compared to control (p = 0.007), and in the electrocautery compared to control (p = 0.026). Incision area was smaller in CDL compared with the control (p = 0.027), and not different between laser and electrocautery groups (p = 0.199). The lateral thermal damage produced by electrocautery was the largest, with a significant difference between laser and electrocautery (p = 0.018), and between electrocautery and control (p = 0.004), whereas the comparison between laser and control showed no significant differences (p = 0.588). The posterior laryngofissure incision using a 980-nm CDL is feasible resulting in smaller incisional area and less lateral thermal damage.