MARCIA UCHOA DE REZENDE
Projetos de Pesquisa
Unidades Organizacionais
Instituto de Ortopedia e Traumatologia, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
LIM/41 - Laboratório de Investigação Médica do Sistema Músculoesquelético, Hospital das Clínicas, Faculdade de Medicina
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conferenceObject RESIDUAL KNEE PAIN AND SYNOVITIS AFTER TOTAL KNEE ARTHROPLASTY TREATED WITH SELECTED EMBOLIZATION OF GENICULAR ARTERIES(2023) REZENDE, M. U.; VALLE, L. G. M.; ASSIS, A. M.; OCAMPOS, G. P.; CARNEVALE, F. C.; AFFONSO, B. B.; GALASTRI, F. L.; NASSER, F.- SCHOOLING OF THE PATIENTS AND CLINICAL APLICATION OF QUESTIONNAIRES IN OSTEOARTHITIS(2014) CAMPOS, Gustavo Constantino de; KOHARA, Marcelo Tomio; REZENDE, Marcia Uchoa; SANTANA, Olga Fugiko Magashima; MOREIRA, Merilu Marins; CAMARGO, Olavo Pires deObjective: To evaluate the consistency of the questionnaires (WOMAC, Lequesne, VAS, SF 36-PCS and SF 36-MCS) when applied in patients with osteoarthritis of the knees (KOA) verifying if age and level of education interfere with the completion of the questionnaires. Method: One hundred and two patients with KOA answered WOMAC, LESQUESNE, VAS and SF-36 questionnaires and provided data correlated with age and education. The internal consistency of the WOMAC questionnaire was verified with Cronbach's alpha. Pearson's correlations between the questionnaires, age and educational level was performed. Results: Mean age was 65 years old. Schooling averaged 7.94 years; WOMAC 47.95; VAS 63.57; Lequesne 12.29; PCS and MCS 31.91 43.68. Cronbach's alpha for WOMAC 0.9. Education did not affect WOMAC response (r=-0.182, p = 0.067) and MCS (r=0.021 / p=0.835), but showed weak but significant correlation with VAS (r=-0.264 / p=0.007), Lequesne (r=0.277, p=0.005) and PCS (r=0.309/ p=0.002). Age showed significant direct correlation only with PCS (r=0.205, p=0.039). Conclusion: The level of education does not interfere with the completion of WOMAC but may interfere with completing VAS, Lequesne and physical component of SF-36.
- VISCOSUPPLEMENTATION IN PATIENTS WITH HEMOPHILIC ARTHROPATHY(2013) ZELADA, Flavio; ALMEIDA, Adriano Marques de; PAILO, Alexandre Felicio; BOLLIGER NETO, Raul; OKAZAKI, Erica; REZENDE, Marcia Uchoa deObjective: To assess whether viscosupplementation with hyaluronic acid in patients with severe hemophilic arthropathy associated with triamcinolone after washing with saline improves joint pain, stiffness, function and quality of life. Methods: Eleven patients with hemophilic arthritis of the knee with and without involvement of other joints (elbows and ankles) underwent joint lavage with saline and subsequent injection of Hylan and triamcinolone in all affected joints. The patients answered the algo-functional (Lequesne and WOMAC), visual analog scale for pain (VAS) and SF-36 (quality of life) questionnaires preoperatively, and at one and three months postoperatively. Results: Pain (VAS and WOMAC pain) and stiffness (WOMAC stiffness) did not show significant improvement (p = 0.3, p = 0.2, p = 0.1, respectively). However function had significant improvement given by WOMAC total and function (averaging 11 points, p = 0.04 and p = 0.001). There was no significant variation in scores in Lequesne's questionnaire (p = 0.1), yet both mental and physical components of SF-36 presented clinically relevant and significant improvements (p = 0.002). Conclusion: Joint lavage with saline followed by injection of corticosteroids and Hylan is effective in the treatment of hemophilic arthropathy, functionally and in quality of life. Level of Evidence IV, Case series.
- BRAZILIAN CONSENSUS STATEMENT ON VISCOSUPPLEMENTATION OF THE HIP (COBRAVI-Q)(2022) SOUSA, Eduardo Branco De; HAMDAN, Paulo Cesar; MENEGASSI, Zartur Jose Barcelos; ALCHAAR, Adrieni Antunes Do Amaral; TIEPPO, Antonio Martins; SOUZA, Caio Goncalves De; PINHEIRO, Carlos Bruno Reis; ALMEIDA, Cyro Scala De; ROCHA, Eduardo De Melo Carvalho; CUNHA, Fabiano Goncalves; PACHECO, Ivan; REZENDE, Marcia Uchoa De; SOUZA, Marcio Passini Goncalves De; SILVA, Marcos Britto Da; CAMPOS, Gustavo Constantino DeObjective: The Brazilian Consensus on Hip Viscosupplementation aims to generate a referential and consensual source from the theoretical knowledge and clinical experience of specialists in the field. Methods: A multidisciplinary panel was formed with 15 specialists (sports medicine, orthopedists, physiatrists and rheumatologists), based on clinical and academic experience in the use of viscosupplementation of the hip. 12 statements were prepared, discussed and voted. Each panelist gave a value between 0 and 10 on a Likert scale, specifying their level of agreement with the statement. Results: The panel reached a consensus on several aspects of viscosupplementation of the hip, with emphasis on the following statements: best indication is for mild to moderate hip arthrosis; it may be indicated in severe osteoarthritis; results may vary according to the characteristics of the viscosupplement used; Viscosupplementation should not be performed as an isolated procedure, but in conjunction with other rehabilitation and pharmacological measures; best injection technique should be based on anatomical references coupled with imaging guidance; it is a cost-effective procedure. Conclusion: Viscosupplementation is a safe and effective therapy for hip osteoarthritis, even in severe cases. Guided injection is recommended.
conferenceObject ONE-YEAR RESULTS OF GENICULAR ARTERIES EMBOLIZATION AS TREATMENT OF KNEE OA(2023) REZENDE, M. U.; VALLE, L. G. M.; ASSIS, A. M.; OCAMPOS, G. P.; CARNEVALE, F. C.; AFFONSO, B. B.; GALASTRI, F. L.; NASSER, F.- PREVALENCE OF OSTEOPOROSIS IN PATIENTS AWAITING TOTAL HIP ARTHROPLASTY(2015) DOMINGUES, Vitor Rodrigues; CAMPOS, Gustavo Constantino de; PLAPLER, Perola Grimberg; REZENDE, Marcia Uchoa deObjective: To evaluate the prevalence of osteoporosis in patients awaiting total hip arthroplasty. Method: Twenty-nine patients diagnosed with hip osteoarthritis awaiting primary total arthroplasty of the hip answered WOMAC questionnaire, VAS and questions about habits, osteoporosis and related diseases. Bone mineral densitometry of the lumbar spine and hips and laboratory tests (complete blood count and examination of calcium metabolism) were performed. Weight and height were measured to calculate body mass index (BMI). The evaluated quantitative characteristics were compared between patients with and without osteoporosis using the Mann-Whitney tests. Results: Thirteen men and 16 women with a mean age of 61.5 years old, WOMAC 51.4; EVA 6.4 and BMI 27.6 were evaluated. The prevalence of osteoporosis was 20.7%, and 37.9% had osteopenia. Patients with osteoporosis were older than patients without osteoporosis (p=0.006). The mean bone mineral density of the femoral neck without hip osteoarthritis was lower than the affected side (p=0.007). Thirty-five percent of patients did not know what osteoporosis is. Of these, 30% had osteopenia or osteoporosis. Conclusion: osteoarthritis and osteoporosis may coexist and the population waiting for total hip arthroplasty should be considered at risk for the presence of osteoporosis.
- CURRENT CONCEPTS IN OSTEOARTHRITIS(2013) REZENDE, Marcia Uchoa de; CAMPOS, Gustavo Constantino de; PAILO, Alexandre FelicioOsteoarthritis (OA), the most common form of joint disease, affects mainly the hips, knees, hands and feet, leading to severe disability and loss of quality of life, particularly in the elderly population. Its importance grows every year with the aging of the population, with a large increase in the elderly population compared to younger patients. The progressive understanding of the pathophysiology of OA, the perception that the process is not purely mechanical and / or aging, and clarification of the inflammatory pathways involved led recently to the clinical application of various drugs and other measures. This update aims to expose the current concepts on the pathophysiology and treatment of OA.
- COST-EFFECTIVENESS AND BUDGET IMPACT ANALYSIS OF VISCOSUPPLEMENTATION WITH ORTHOVISC (TM) (HYALURONAN) IN KNEE OSTEOARTHRITIS, FROM THE BRAZILIAN PRIVATE HEALTH CARE SYSTEM PERSPECTIVE(2012) REZENDE, M. U.; HERNANDEZ, A. J.; NAMBA, M. M.; FERNANDES, R. A.; TAKEMOTO, M. L. S.; SANTOS, P. M. L.; REPSOLD, D. M.; SILVA, R. C.; ANDRADE, P. C.
- ANALYSIS AND CORRELATION OF PHYSICAL THERAPY TESTS, PAIN, FUNCTION AND QUALITY OF LIFE QUESTIONNAIRES IN PATIENTS FROM PARQVE (PROJECT ARHTRITIS RECOVERING QUALITY OF LIFE BY MEANS OF EDUCATION)(2015) FARIAS, F. E.; SILVA, C. A.; CERNIGOY, C. H.; REZENDE, M. U.
- Pilot study of the effect of therapeutic photobiomodulation on postoperative pain in knee arthroplasty(2022) REZENDE, Marcia Uchoa de; VARONE, Bruno Butturi; MARTUSCELLI, Diego Ferreira; OCAMPOS, Guilherme Pereira; FREIRE, George Miguel Goes; PINTO, Nathali Cordeiro; SOUSA, Marcelo Victor Pires deAbstract Nine participants undergoing primary TKA submitted to spinal anesthesia, sedation, ultrasound-guided obturator and Femoral nerve Block analgesia, and photobiomodulation Therapy (FBMT) were evaluated regarding postoperative pain and morphine consumption. FBMT sessions were performed in the Immediate Postoperative period (IPO) and after 24 hours. Participants received 16.7±15 mg of morphine up to the third postoperative day. At IPO, mean pain score was 4.8 ± 3.2 and 5.6 ± 3.5, at rest and on movement, respectively. Photo biomodulation therapy can be considered an option for mitigating pain for patients undergoing TKA.