MUCIO TAVARES DE OLIVEIRA JUNIOR
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina
28 resultados
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conferenceObject Endovascular Therapeutic Hypothermia Is Feasible as an Adjuvant Therapy in Acute ST-Segment Elevation Myocardial Infarction Patients Without Delay in Door-to-Balloon Time(2019) DALLAN, Luis; GIANNETTI, Natali; DAE, Michael; POLASTRI, Thatiane; ROCHITTE, Carlos Eduardo; NOMURA, Cesar Higa; HAJJAR, Ludhmila Abrahao; BERNOCHE, Claudia; LAGE, Silvia; LIMA, Felipe; NICOLAU, Jose Carlos; TAVARES JR., Mucio; RIBEIRO, Expedito; KALIL JR., Roberto; LEMOS, Pedro A.; TIMERMAN, Sergio- Endovascular therapeutic hypothermia adjunctive to percutaneous coronary intervention in acute myocardial infarction: realistic simulation as a game changer(2022) DALLAN, Luis Augusto Palma; DAE, Michael; GIANNETTI, Natali Schiavo; POLASTRI, Tathiane Facholi; LIMA, Marian Keiko Frossard; ROCHITTE, Carlos Eduardo; HAJJAR, Ludhmila Abrahao; MARTIN, Claudia Yanet Bernoche San; LIMA, Felipe Gallego; NICOLAU, Jose Carlos; JR, Mucio Tavares de Oliveira; DALLAN, Luis Alberto Oliveira; SILVA, Expedito Eustaquio Ribeiro da; FILHO, Roberto Kalil; ABIZAID, Alexandre; LEMOS NETO, Pedro Alves; TIMERMAN, SergioBackground: Endovascular therapeutic hypothermia (ETH) reduces the damage by ischemia/reperfusion cell syndrome in cardiac arrest and has been studied as an adjuvant therapy to percutaneous coronary intervention (PCI) in ST-elevation myocardial infarction (STEMI). New available advanced technology allows cooling much faster, but there is paucity of resources for training to avoid delays in door-to-balloon time (DTB) due to ETU and subsequently coronary reperfusion, which would derail the procedure. The aim of the study was to describe the process for the development of a simulation, training & educational protocol for the multidisciplinary team to perform optimized ETH as an adjunctive therapy for STEMI. Methods and results: We developed an optimized simulation protocol using modern mannequins in different realistic scenarios for the treatment of patients undergoing ETH adjunctive to PCI for STEN s starting from the emergency room, through the CathLab, and to the intensive care unit (ICU) using the Proteus (R) Endovascular System (loll Circulation Inc (TM), San Jose, CA, USA). The primary endpoint was door-to-balloon (DTB) time. We successfully trained 361 multidisciplinary professionals in realistic simulation using modern mannequins and sham situations in divisions of the hospital where real patients would be treated. The focus of simulation and training was logistical optimization and educational debriefing with strategies to reduce waste of time in patient's transportation from different departments, and avoiding excessive rewanning during transfer. Afterwards, the EHT protocol was successfully validated in a trial randomizing 50 patients for 18 minutes cooling before coronary recanalization at the target temperature of 32 +/- 1.0 degrees C or PCI-only. A total of 35 patients underwent FM (85.7% [30/35] in 90 +/- 15 minutes), without delays in the mean door-to-balloon time for primary PCI when compared to 15 control group patients (92.1 minutes versus 87 minutes, respectively; p = 0.509). Conclusions: Realistic simulation, intensive training and educational debriefing for the multidisciplinary team propitiated feasible endovascular therapeutic hypothermia as an adjuvant therapy to primary PCI in STEM.
conferenceObject Training, Simulation and Validation of Therapeutic Hypothermia as an Adjuvant Treatment in St Segment Elevation Myocardial Infarction(2018) DALLAN, Luis Augusto; RIBEIRO, Marcelo; GIANNETTI, Natali; ROCHITTE, Carlos; NOMURA, Cesar H.; HAJJAR, Ludhmila A.; BERNOCHE, Claudia Y.; LAGE, Silvia G.; NICOLAU, Jose Carlos; OLIVEIRA, Mucio T.; POLASTRI, Thatiane F.; RIBEIRO, Expedito E.; KALIL FILHO, Roberto; LEMOS NETO, Pedro A.; TIMERMAN, SergioconferenceObject Safety of Endovascular Therapeutic Hypothermia as an Adjuvant Therapy in Acute ST Segment Elevation Myocardial Infarction(2017) DALLAN, Luis A.; RIBEIRO, Marcelo; GIANNETTI, Natali; ROCHITTE, Carlos; NOMURA, Cesar; HAJJAR, Ludhmila; LAGE, Silvia; LIMA, Felipe G.; SOEIRO, Alexandre; NICOLAU, Jose C.; TAVARES, Mucio; NETO, Pedro A. Lemos; TIMERMAN, Sergio; KALIL, Robertobook Cardiologia de emergências em fluxogramas(2015) SOEIRO, Alexandre de Matos; LEAL, Tatiana de Carvalho Andreucci Torres; OLIVEIRA JR., Múcio Tavares de; KALIL FILHO, RobertoconferenceObject Cooling as an Adjunctive Therapy to Percutaneous Intervention in Acute Myocardial Infarction: COOL-MI InCor Trial(2020) DALLAN, Luis Augusto; GIANNETTI, Natali; ROCHITTE, Carlos Eduardo; POLASTRI, Thatiane; BERNOCHE, Claudia; HAJJAR, Ludhmila Abrahao; LIMA, Felipe; NICOLAU, Jose Carlos; TAVARES JR., Mucio; DAE, Michael; RIBEIRO, Expedito; KALIL JR., Roberto; LEMOS, Pedro A.; TIMERMAN, Sergio- Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instável e Infarto Agudo do Miocárdio sem Supradesnível do Segmento ST (II Edição, 2007) - Atualização 2013/2014(2014) NICOLAU, JC; TIMERMAN, A; MARIN-NETO, JA; PIEGAS, LS; BARBOSA, CJDG; FRANCI, A; AVEZUM JR., A; CARVALHO, ACC; MARKMAN FILHO, B; POLANCZYK, CA; ROCHITTE, CE; SERRANO JÚNIOR, CV; PRECOMA, DB; SILVA JUNIOR, DG; ALBUQUERQUE, DC; STEFANINI, E; KNOBEL, E; JATENE, FB; FERES, F; MORCERF, FAP; GANEM, F; LIMA FILHO, FA; FEITOSA FILHO, GS; FERREIRA, JFM; MENEGHETTI, JC; SARAIVA, JFK; SILVA, LS; MAIA, LN; BARACIOLI, LM; LISBOA, LAF; DALLAN, LAO; BODANESE, LC; ANDRADE, MD; OLIVEIRA JÚNIOR, M; DUTRA, OP; COELHO, OR; LEÃES, PE; ALBUQUERQUE, PF; LEMOS, P; KALIL, R; COSTA, RVC; ESPORCATE, R; MARINO, RL; BOTELLHO, RV; MENEGHELO, RS; SPROVIERI, SR; TIMERMAN, S; MATHIAS JÚNIOR, W
conferenceObject Sonothrombolysis Improves Left Atrial Pressure and Volume in Patients With ST Elevation Acute Myocardial Infarction(2020) CHIANG, Hsu Po; AGUIAR, Miguel; TAVARES, Bruno; MATHIAS, Wilson; BORGES, Bruno C.; OLIVEIRA, Mucio; SOEIRO, Alexandre D.; NICOLAU, Jose C.; SBANO, Joao; GOLDSWEIG, Andrew M.; KALIL FILHO, Roberto; RAMIRES, Jose A.; PORTER, Thomas R.; TSUTSUI, Jeane M.conferenceObject THE IMPACT OF SONOTHROMBOLYSIS ON LEFT VENTRICULAR DIASTOLIC FUNCTION AND LEFT ATRIAL MECHANICS IN PATIENTS WITH ST ELEVATION MYOCARDIAL INFARCTION(2020) CHIANG, Hsu; AGUIAR, Miguel Osman; TAVARES, Bruno Garcia; MATHIAS JR., Wilson; BORGES, Bruno Carter; AZEVEDO, Luciene; OLIVEIRA, Mucio; SOEIRO, Alexandre; NICOLAU, Jose C.; RIBEIRO, Henrique B.; SBANO, Joao Cesar; GOLDSWEIG, Andrew; KALIL-FILHO, Roberto; RAMIRES, Jose; PORTER, Thomas; TSUTSUI, JeaneconferenceObject Effects of High Mechanical Index Impulses From a Diagnostic Ultrasound Transducer During an Intravenous Ultrasound Contrast Infusion in Preventing Adverse Left Ventricular Remodeling in Acute ST Segment Myocardial Infarction(2016) MATHIAS, Wilson; TSUTSUI, Jeane M.; TAVARES, Bruno G.; AGUIAR, Miguel O.; OLIVEIRA, Mucio T.; SOEIRO, Alexandre; LEMOS, Pedro A.; RAMIRES, Jose; KALIL, Roberto; PORTER, Thomas R.
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