VERA HERMINA KALIKA KOCH
Projetos de Pesquisa
Unidades Organizacionais
Instituto da Criança, Hospital das Clínicas, Faculdade de Medicina
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/36 - Laboratório de Pediatria Clínica, Hospital das Clínicas, Faculdade de Medicina - Líder
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
conferenceObject Pediatric peritoneal dialysis in Brazil: document by the Brazilian Society of Nephrology, Brazilian Society of Pediatrics, Brazilian Association of Organ Transplantation, and the Brazilian Association of Dialysis and Transplant Centers.(2023) PENIDO, Maria Goretti Moreira Guimaraes; PALMA, Lilian Monteiro Pereira; BRESOLIN, Nilzete Liberato; TAVARES, Marcelo Sousa; SYLVESTRE, Lucimary Castro; ANDRADE, Olberes Vitor Braga de; BERNARDES, Rejane Paula; BANDEIRA, Maria de Fatima Santos; GARCIA, Clotilde Druck; KOCH, Vera Hermina Kalika; BELANGERO, Vera Maria Santoro; UHLMANN, Anelise; KAUFMAN, Arnauld; ANDRADE, Maria Cristina; SILVA, Roxana Almeida Roque Fontes- Hypertension in the Developing World(2023) KOCH, V. H.Hypertension is a major global chronic noncommunicable disease (NCD). Despite continued efforts to establish public policies to ensure surveillance and monitoring, the absolute numbers of patients affected by hypertension in low- and middle-income countries are likely to grow, as economic improvement favors longer life expectancy. Increasing longevity provides longer periods of exposure to the risk factors of cardiovascular disease (CVD), resulting in a greater probability of clinical manifestation of CVD events, especially because of the lack of awareness and insufficient treatment of the affected individuals. The survivors of an economic transition period are more likely to present the phenotype of lower birth weight coupled with either stunting or a higher body mass index in childhood or adulthood, which appears to be associated with the highest risks of morbid cardiovascular, renal, and metabolic outcomes into adulthood. The combination of population-wide and individual interventions may save millions of lives and considerably reduce human suffering from NCDs. © Springer Nature Switzerland AG 2023.
- The challenges of the pandemic and the vaccination against covid-19 in pediatric patients with kidney disease(2023) SOEIRO, Emilia Maria Dantas; PENIDO, Maria Goretti Moreira Guimaraes; PALMA, Lilian Monteiro Pereira; BRESOLIN, Nilzete Liberato; LIMA, Eduardo Jorge da Fonseca; KOCH, Vera Hermina Kalika; TAVARES, Marcelo de Sousa; SYLVESTRE, Lucimary; BERNARDES, Rejane de Paula; GARCIA, Clotilde Druck; ANDRADE, Maria Cristina de; KAUFMAN, Arnauld; CHOW, Charles Yea Zen; MARTINS, Suelen Bianca Stopa; CAMARGO, Suzana Friedlander Del NeroThe covid-19 vaccine confers direct protection and reduces transmission rates of the virus and new variants. Vaccines from Pfizer/BioNTech and CoronaVac have been cleared for children in Brazil. They are safe, effective, and immunogenic. There are no known complications associated with the use of steroids or vaccines in pediatric patients with covid-19 and nephrotic syndrome. With or without immunosuppression, these patients are not at increased risk of severe covid-19, and steroids are safe for them. A milder form of covid-19 occurs in patients with chronic kidney disease without the need for hospitalization. The vaccine response may be reduced and/or the duration of antibodies after vaccination may be shorter than in the general population. However, considering risk of exposure, vaccination against covid-19 is recommended. It is believed that patients with hemolytic-uremic syndrome are at higher risk of severe covid-19. Vaccination is recommended, although specific data on the safety and efficacy of the covid-19 vaccine are limited. There is agreement that the benefits of induced immunity outweigh the risks of immunization. Vaccination against covid-19 is recommended for children and adolescents needing kidney transplantation or who have undergone transplantation. These patients present decreased immune response after vaccination, but immunization is recommended because the benefits outweigh the risks of vaccination. Current recommendations in Brazil stipulate the use of the messenger RNA vaccine. This paper aims to provide pediatric nephrologists with the latest knowledge about vaccination against covid-19 for children with kidney disease.
- Risk factors of acute kidney injury in very low birth weight infants in a tertiary neonatal intensive care unit(2023) MORAES, Lucas Hirano Arruda; KREBS, Vera Lucia Jornada; KOCH, Vera Hermina Kalika; MAGALHAES, Natalia Assis Medeiros; CARVALHO, Werther Brunow deObjective: Acute kidney injury (AKI) in the neonatal period is associated with worst outcomes as increased mortality and increased length of hospital stay. Very low birth weight (VLBW) newborns are at higher risk for developing several other conditions that are associated with worst outcomes. Understanding the risk factors for AKI may help to prevent this condition and improve neonatal care for this population. Methods: This retrospective cohort study included 155 very low birth weight newborns admitted between 2015 and 2017. The authors compared the newborns who developed neonatal AKI with the non-AKI group and analyzed the main risk factors for developing AKI in the population. The authors also performed an analysis of the main outcomes defined as the duration of mechanical ventilation, length of stay, and death. Results: From the cohort, a total of 61 (39.4%) patients had AKI. The main risk factors associated with Neonatal AKI were necrotizing enterocolitis (aOR 7.61 [1.69 - 34.37]; p = 0.008), neonatal sepsis (aOR 2.91 [1.17 - 7.24], p = 0.021), and hemodynamic instability (aOR 2.99 [1.35 - 6.64]; p = 0.007). Neonatal AKI was also associated with an increase in the duration of mechanical ventilation in 9.4 days (p = 0.026) and in an increase in mortality 4 times (p = 0.009), after adjusting for the other variables. Conclusion: The present results highlight the importance of minimizing sepsis and necrotizing enterocolitis, as well as the importance of identifying hemodynamic instability, to prevent AKI and diminish the burden of morbimortality in VLBW newborns. (c) 2022 Sociedade Brasileira de Pediatria.
bookPart Aspectos laboratoriais em nefrologia(2023) SUMITA, Nairo Massakazu; KOCH, Vera Hermina Kalika