SAMUEL PADOVANI STEFFEN
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
5 resultados
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conferenceObject A New Allocation System for Priorization in Heart Transplantation in the State of Sao Paulo - Brazil: Its Impact on Patients in ECMO(2022) STEFFEN, Samuel P.; GAIOTTO, Fabio A.; GASPAR, Shyrline F.; SANTOS, Ronaldo Honorato B.; FILHO, Domingos D. L.; BACAL, Fernando; JATENE, Fabio B.- Heterotopic Heart Transplantation as a Left Ventricular Biological Assistance: a New Two-Stage Method Proposal(2020) GAIOTTO, Fabio Antonio; BARBOSA FILHO, Antonio Carlos de Almeida; TENORIO, Davi Freitas; STEFFEN, Samuel Padovani; JATENE, Fabio B.Since Barnard's first heterotopic heart transplant in 1974, Copeland's method has been the greatest contribution to heterotopic transplants but has the drawback of donor's right ventricular atrophy. This new method proposes a modification in the anastomosis of the superior vena cava aiming to pre-serve donor's right ventricular function by decompressing the pulmonary territory and reducing the pulmonary arterial pressure, as a biological ventricular assist device. Finally, a second intervention is proposed, where a ""twist"" is performed to place the donor's heart in an orthotopic position after re-moval of the native heart. A pioneering research on this method received approval from the ethics committee of the Heart Institute of Sao Paulo. We believe that this method has the potential to im-prove quality of life in a selected group of patients.
- Quadricuspid Aortic Valve: Three Cases Report and Literature Review(2019) VERONESE, Elinthon Tavares; BRANDAO, Carlos Manuel de Almeida; STEFFEN, Samuel Padovani; POMERANTZEFF, Pablo; JATENE, Fabio B.Quadricuspid aortic valve (QAV) is a rare cardiac malformation. Many cases are incidentally diagnosed in aortic surgeries or autopsies and it usually appears as an isolated anomaly. The most widely classification used is the one by Hurwitz and Roberts[1], which divides 7 alphabetical subtypes based on the cusps size. The aim of this report is to describe three different anatomic presentations of this rare aortic valve anomaly.
- Severe and Moderate Primary Graft Dysfunction in Adult Heart Recipients(2023) STEFFEN, Samuel Padovani; TENORIO, Davi Freitas; CIRILLO, Guilherme Carvalhal Gnipper; GASPAR, Shirlyne Fabianni; OLIVEIRA, Karen Amanda Soares de; GAIOTTO, Fabio Antonio; JATENE, Fabio B.Introduction: The aims of this study were to determine the incidence of severe and moderate primary graft dysfunction (PGD) in our center, to identify, retrospectively, donors' and recipients' risk factors for PGD development, and to evaluate the impact of PGD within 30 days after heart transplantation.Methods: Donors' and recipients' medical records of 64 consecutive adult cardiac transplantations performed between January 2016 and June 2017 were reviewed. The International Society for Heart and Lung Transplantation (ISHLT) criteria were used to diagnose moderate and severe PGD. Associations of risk factors for combined moderate/severe PGD were assessed with appropriate statistical analyses.Results: Sixty-four patients underwent heart transplantation in this period. Twelve recipients (18.7%) developed severe or moderate PGD. Development of PGD was associated with previous donor cardiopulmonary resuscitation and a history of prior heart surgery in the recipient (P=0.01 and P=0.02, respectively). The 30-day in hospital mortality was similar in both PGD and non-PGD patients.Conclusion: The use of the ISHLT criteria for PGD is important to identify potential risk factor. The development of PGD did not affect short-term survival in our study. More studies should be done to better understand the pathophysiology of PGD.
conferenceObject Use of Grafts With Extended Ischemic Time (Above 4 Hours Or More): Analysis of the Experience of the Largest Brazilian Heart Transplant Center, From 2013 to 2022(2022) SANTOS, Ronaldo Honorato; GAIOTTO, Fabio A.; STEFFEN, Samuel P.; FILHO, Domingos D. L.; GASPAR, Shirlyne F. D.; BACAL, Fernando; JATENE, Fabio B.