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Departamento de Radiologia, Faculdade de Medicina - Docente
Instituto de Radiologia, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/44 - Laboratório de Ressonância Magnética em Neurorradiologia, Hospital das Clínicas, Faculdade de Medicina

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Autor: CHALA, Luciano Fernandes ×

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Agora exibindo 1 - 6 de 6
  • bookPart
    Carcinoma de mama: diagnóstico
    (2016) MENDES, Daniele Carvalho Calvano; CHALA, Luciano Fernandes; BARROS, Nestor de; FILASSI, Jose Roberto
  • article 4 Citação(ões) na Scopus
    Imaging of male breast disease: the good, the bad and the ugly - A pictorial review
    (2020) VIANAA, Marcela Pacheco; TUCUNDUVAA, Tatiana Cardoso de Mello; TORRES, Ulysses S.; AGUILLARA, Vera Lucia Nunes; BRESCIANI, Barbara Helou; SHIMIZU, Carlos; CHALA, Luciano Fernandes; BARROS, Nestor de; MELLO, Giselle Guede Netto de
    The male breast is affected by a broad spectrum of conditions, ranging from benign to malignant, many of which are similar to those occurring in its female counterpart. Despite the challenge motivated by different imaging characteristic features, correct imaging interpretation in male breast disease may aid at differentiation between benign and suspected conditions, narrow the differential diagnosis and guide subsequent management. The purpose of this review is to showcase a wide array of male breast diseases, discuss their imaging presentations and key features for diagnosis.
  • bookPart
    Métodos radiológicos
    (2013) COSTA, Daniel Nóbrega da Costa; PINHO, Marco da Cunha; GARCIA, Marcio Ricardo Taveira; BEZERRA, Regis Otaviano França; GARCIA, Rodrigo Gobbo; JULIO, Thiago; SUGUINO, Silvio; MARCELINO, Antônio Sergio Zafred; CHALA, Luciano Fernandes; BARROS, Nestor de; MENEZES, Marcos Roberto de; CERRI, Giovanni Guido
  • article 23 Citação(ões) na Scopus
    MRI to Predict Nipple Involvement in Breast Cancer Patients
    (2016) PIATO, Jose Roberto Morales; ANDRADE, Roberta Dantas Jales Alves de; CHALA, Luciano Fernandes; BARROS, Nestor de; MANO, Max Senna; MELITTO, Alexandre Santos; GONCALVES, Rodrigo; SOARES JUNIOR, Jose Maria; BARACAT, Edmund Chada; FILASSI, Jose Roberto
    OBJECTIVE. The selection of breast cancer patients as candidates for nipple-sparing mastectomy (NSM) is dependent on the preoperative detection of neoplastic involvement of the nipple-areola complex (NAC). This cross-sectional study was designed to evaluate the accuracy of preoperative breast MRI as a noninvasive method to predict neoplastic involvement of the nipple. MATERIALS AND METHODS. We included 165 female breast cancer patients with a surgical plan that included total mastectomy or breast conservation surgery with the removal of the NAC. All patients underwent MRI before surgery on a 1.5-T unit with a 4-channel in vivo dedicated surface breast coil. One radiologist who was blinded to the results of the histologic evaluations of the specimens evaluated the MRI studies. RESULTS. Of the 170 mastectomy specimens evaluated, 37 (21.8%) had neoplastic involvement of the NAC. The MRI findings of enhancement between the index lesion and the NAC and of nipple retraction were considered statistically significant predictors of nipple involvement in breast cancer patients (p < 0.01 and p = 0.01, respectively). The negative predictive value of the combination of these MRI findings was 83.3%. CONCLUSION. Breast MRI is a safe noninvasive method to preoperatively evaluate breast cancer patients eligible for NSM with a high specificity and a high negative predictive value when enhancement between the index lesion and the nipple and nipple retraction are analyzed.
  • article 27 Citação(ões) na Scopus
    Mammography-based screening program: preliminary results from a first 2-year round in a Brazilian region using mobile and fixed units
    (2012) HAIKEL JR., Raphael Luiz; MAUAD, Edmundo Carvalho; SILVA, Thiago Buosi; MATTOS, Jaco Saraiva de Castro; CHALA, Luciano Fernandes; LONGATTO-FILHO, Adhemar; BARROS, Nestor de
    Background: Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer deaths among women worldwide. The use of mobile mammography units to offer screening to women living in remote areas is a rational strategy to increase the number of women examined. This study aimed to evaluate results from the first 2 years of a government-organized mammography screening program implemented with a mobile unit (MU) and a fixed unit (FU) in a rural county in Brazil. The program offered breast cancer screening to women living in Barretos and the surrounding area. Methods: Based on epidemiologic data, 54 238 women, aged 40 to 69 years, were eligible for breast cancer screening. The study included women examined from April 1, 2003 to March 31, 2005. The chi-square test and Bonferroni correction analyses were used to evaluate the frequencies of tumors and the importance of clinical parameters and tumor characteristics. Significance was set at p < 0.05. Results: Overall, 17 964 women underwent mammography. This represented 33.1% of eligible women in the area. A mean of 18.6 and 26.3 women per day were examined in the FU and MU, respectively. Seventy six patients were diagnosed with breast cancer (41 (54%) in the MU). This represented 4.2 cases of breast cancer per 1000 examinations. The number of cancers detected was significantly higher in women aged 60 to 69 years than in those aged 50 to 59 years (p < 0.001) or 40 to 49 years (p < 0.001). No difference was observed between women aged 40 to 49 years and those aged 50 to 59 years (p = 0.164). The proportion of tumors in the early (EC 0 and EC I) and advanced (CS III and CS IV) stages of development were 43.4% and 15.8%, respectively. Conclusions: Preliminary results indicate that this mammography screening program is feasible for implementation in a rural Brazilian territory and favor program continuation.
  • article 10 Citação(ões) na Scopus
    Sarcomas of the breast: findings on mammography, ultrasound, and magnetic resonance imaging
    (2018) MATSUMOTO, Renato Augusto Eidy Kiota; HSIEH, Su Jin Kim; CHALA, Luciano Fernandes; MELLO, Giselle Guedes Netto de; BARROS, Nestor de
    Abstract Sarcomas of the breast belong to a heterogeneous group of breast tumors of mesenchymal origin, without epithelial components. These tumors can be primary or secondary (after previous treatment for breast cancer), are rare, present aggressive behavior, and have a poor prognosis. They occur mainly in women between 45 and 50 years of age, with the exception of angiosarcomas, which can occur in younger patients. Clinically, breast sarcomas manifest as palpable, mobile, rapidly growing masses, without skin thickening, axillary lymphadenopathy, or nipple discharge. Although the imaging findings are non specific, they can be suggestive of sarcoma. For instance, a solitary mass showing rapid growth, with circumscribed or indistinct margins and, a complex (solid-cystic) or heterogeneous echotexture, without axillary lymph node involvement, can raise the suspicion of sarcoma. The treatment is not well established, because of the rarity and heterogeneity of this type of neoplasm. The principles of treatment for sarcoma of the breast have been addressed only in small cohort studies. In most cases, the treatment of choice is surgery without axillary lymphadenectomy.