NELSON WOLOSKER
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Cirurgia, Faculdade de Medicina - Docente
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/02 - Laboratório de Anatomia Médico-Cirúrgica, Hospital das Clínicas, Faculdade de Medicina - Líder
3 resultados
Resultados de Busca
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- A Single Bout of Arm-crank Exercise Promotes Positive Emotions and Post-Exercise Hypotension in Patients with Symptomatic Peripheral Artery Disease(2017) CAVALCANTE, B. R.; RITTI-DIAS, R. M.; SOARES, A. H. G.; LIMA, A. H.; CORREIA, M. A.; MATOS, L. D. De; GOBBI, F.; LEICHT, A. S.; WOLOSKER, N.; CUCATO, G. G.Objective/Background: The objective was to analyze the acute effects of a single bout of arm cranking exercise on affective and cardiovascular parameters in patients with symptomatic peripheral artery disease (PAD). Methods: This was a prospective, controlled, crossover study. Eleven men with symptomatic PAD underwent two experimental sessions in a random order: control or arm crank exercise (15 x 2 minutes bouts of arm crank exercise interrupted by 2 minutes rest intervals). During exercise, ratings of perceived exertion (Borg scale) and affective responses (pleasure/displeasure) were obtained at the first, fifth, tenth, and fifteenth bouts. Before and after the experimental sessions, cardiovascular parameters (blood pressure and heart rate) were obtained. Data were analysed by a two-way repeated measure analysis of variance with significance achieved at p < .05. Results: During the arm crank exercise, patients reported positive feelings of pleasure. During exercise, heart rate (HR) remained within 80-90% of peak HR. Additionally, patients performed arm crank exercise with moderate levels of perceived exertion (Borg rating of 11-13) and with pleasant affective scores (Feeling Scale of +1 to +5). Blood pressure (systolic, diastolic, and mean) increase was lower after arm crank exercise than for control (greatest net effect: -15 +/- 11 mmHg [p <.001]; -9 +/- 5 mmHg [p <.001]; -9 +/- 6 mmHg [p <.001], respectively), while HR increased (greatest net effect: +9 +/- 6 beats per minute; p <.001). Conclusion: A single bout of arm crank exercise promotes pleasurable feelings while reducing blood pressure in patients with symptomatic PAD.
- Reproducibility of Anaerobic and Pain Thresholds in Male Patients With Intermittent Claudication(2016) CHEHUEN, Marcel da Rocha; CUCATO, Gabriel Grizzo; SAES, Glauco Fernandes; COSTA, Luiz Augusto Riani; LEICHT, Anthony Scott; RITTI-DIAS, Raphael Mendes; WOLOSKER, Nelson; FORJAZ, Claudia Lucia de MoraesPURPOSE: Maximal and submaximal parameters assessed during treadmill tests are used to prescribe exercise training and assess exercise-induced adaptations in patients with intermittent claudication (IC). Although reproducibility of maximal parameters is well documented, the reproducibility of submaximal is not clear. The aim of this study was to identify the reproducibility (reliability and agreement) of heart rate (HR) and oxygen uptake (o(2)) measured at the anaerobic (AT) and the pain (PT) thresholds assessed during a maximal test in patients with IC. METHODS: Twenty male patients with IC underwent 2 cardiopulmonary treadmill tests to maximal pain. The HR ando(2) at the AT and PT were identified, and differences between repeat tests were compared. Reliability was determined by intraclass coefficient correlation (ICC). Agreement was assessed by coefficient of variation (CV), standard error of measurement (SEM), smallest detectable difference (SDD), and limits of agreement (LOA). RESULTS: The o(2) at AT and PT exhibited moderate reliability and moderate/good agreement (ICC = 0.73 and 0.70; CV = 9.6% and 11.1%, respectively). The HR at the AT and PT exhibited high reliability and good agreement (ICC = 0.87 and 0.92; SEM = 3.9 and 3.2 bpm; SDD = 10.8 and 8.8 bpm, respectively). The LOA for o(2) at AT and PT were 20% and for HR 11 bpm. CONCLUSIONS: The o(2) and HR measured at the AT and PT were moderately to highly reproducible in male patients with IC. The HR and o(2) at AT and PT may be used to establish training intensity and evaluate training effectiveness for these patients in clinical practice and research.
- Walking training at the heart rate of pain threshold improves cardiovascular function and autonomic regulation in intermittent claudication: A randomized controlled trial(2017) CHEHUEN, Marcel; CUCATO, Gabriel G.; CARVALHO, Celso Ricardo F.; RITTI-DIAS, Raphael M.; WOLOSKER, Nelson; LEICHT, Anthony S.; FORJAZ, Claudia Lucia M.Objectives: This study investigated the effects of walking training (WT) on cardiovascular function and autonomic regulation in patents with intermittent claudication (IC). Design: Randomized controlled trial. Methods: Forty-two male patients with IC (>= 50 years) were randomly allocated into two groups: control (CG, n = 20, 30 min of stretching exercises) and WT (WTG, n = 22, 15 bouts of 2 min of walking interpolated by 2 min of upright rest-walking intensity was set at the heart rate of pain threshold). Both interventions were performed twice/week for 12 weeks. Walking capacity (maximal treadmill test), blood pressure (auscultatory), cardiac output (CO2 rebreathing), heart rate (ECG), stroke volume, systemic vascular resistance, forearm and calf vascular resistance (plethysmography), and low (LF) and high frequency (HF) components of heart rate variability and spontaneous baroreflex sensitivity were measured at baseline and after 12 weeks of the study. Results: WT increased total walking distance (+302 +/- 85 m, p = 0.001) and spontaneous baroreflex sensitivity (+2.13 +/- 1.07 ms/mmHg, p = 0.02). Additionally, at rest, WT decreased systolic and mean blood pressures (-10 +/- 3 and -5 +/- 2 mmHg, p = 0.001 and p = 0.01, respectively), cardiac output (-0.37 +/- 0.24 l/min, p = 0.03), heart rate (-4 +/- 2 bpm, p = 0.001), forearm vascular resistance (-8.5 +/- 2.8 U, p = 0.02) and LF/HF (-1.24 +/- 0.99, p = 0.001). No change was observed in the CG. Conclusions: In addition to increasing walking capacity, WT improved cardiovascular function and autonomic regulation in patients with IC.