ALEXANDRE SILVA E SILVA

(Fonte: Lattes)
Índice h a partir de 2011
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Lattes
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Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina
LIM/58 - Laboratório de Ginecologia Estrutural e Molecular, Hospital das Clínicas, Faculdade de Medicina

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  • conferenceObject
    In Bag Morcellation: details and logistics of the technique
    (2016) FERNANDES, R.; ARAUJO, M.; SILVA, A. Silva e; CARVALHO, P. Mancusi de; ANTON, C.; GENTA, M. L. Nogueira Dias; RIBEIRO JR., A. Dias; SAMPAIO, D.; MIGLINO, G.; SADALLA, J. C.; CARVALHO, J. Paula
  • conferenceObject
    IATROGENIC INJURY OF THE OBTURATOR NERVE DURING PELVIC LAPAROSCOPIC LYMPHADENECTOMY: ANALYSIS OF THE CORRECTION 5 YEARS LATER
    (2016) DIAS, A. J. Ribeiro; SILVA, A. Silva e; FERNANDES, R. Pinto; ANTON, C.; ARAUJO, M.; MORAES, A.; BARROS, L.; CARVALHO, J. P.; BARACAT, E. C.
  • article
    Functional Reconstruction of Temporomandibular Joint after Resection of Pigmented Villonodular Synovitis with Extension to Infratemporal Fossa and Skull Base: A Case Report
    (2016) VELLUTINI, Eduardo de Arnaldo Silva; ALONSO, Nivaldo; ARAP, Sergio Samir; GODOY, Luis Felipe Silva; SOUZA, Ricardo Antenor de Souza e; MATTEDI, Romulo Loss; OLIVEIRA, Matheus Fernandes de
    Introduction Pigmented villonodular synovitis (PVNS) is a benign but aggressive lesion arising from sinovia. The temporomandibular joint (TMJ) is hardly ever involved. Methods We describe a case of PVNS arising in the left TMJ involving infratemporal fossa soft tissue and the skull base; we also present the reconstruction. Results A 37-year-old woman had progressive mandibular swelling for 6 months. Computed tomography of the skull revealed an osteolytic lesion in the left TMJ, involving the upper mandible, condyle, and glenoid fossa and extending to the infratemporal fossa and fossa media through a defect in temporal bone. Surgical management included a left pterional craniotomy to reach the temporal skull base and resect the intracranial tumor and a facial approach with partial leftmandibulectomy and resection of left condyle, glenoid fossa, and tumor removal in infratemporal fossa. Mandible function was restored with prosthetic reconstruction of the condyle. She progressively started to eat solid foods after 3 months, becoming increasingly functional and asymptomatic. At 30 months' follow-up, she had no sign of tumoral recurrence and showed asymptomatic and normal TMJ function. Conclusion PVNS should be considered in the differential diagnosis of bone neoplasms affecting young patients. In such cases, radical excision is mandatory and TMJ prosthesis for local reconstruction may be used to preserve functionality.
  • conferenceObject
    Borderline Ovarian Tumors: 15 year experience from a Single institute
    (2016) FERNANDES, R.; ANTON, C.; SILVA, A. Silva e; ARAUJO, M.; SAMPAIO, D.; MIGLINO, G.; CARVALHO, J. P. Mancusi de; RIBEIRO JR., A. Dias; SADALLA, J. C.; GENTA, M. L. Nogueira Dias; CARVALHO, J. Paula
  • conferenceObject
    Oncologic safety of laparoscopy in the surgical treatment of type II endometrial cancer.
    (2016) FAVERO, Giovanni; ANTON, Cristina; LE, Xin; KHLER, Christhardt; PFIFFER, Tatiana; DOGAN, Nasuh Utku; BARACAT, Edmund Chada; SILVA, Alexandre Silva; CARVALHO, Jesus Paula
  • article 29 Citação(ões) na Scopus
    Oncologic Safety of Laparoscopy in the Surgical Treatment of Type II Endometrial Cancer
    (2016) FAVERO, Giovanni; ANTON, Cristina; LE, Xin; SILVA, Alexandre Silva e; DOGAN, Nasuh Utku; PFIFFER, Tatiana; KOEHLER, Christhardt; BARACAT, Edmund Chada; CARVALHO, Jesus Paula
    Background: Laparoscopy is considered the method of choice in the operative treatment of type I endometrial carcinoma (EC). However, there is a paucity of data regarding the safety of endoscopy for type II EC because these malignancies have several biological similarities with ovarian cancer. Objectives: This study aimed to evaluate the feasibility, operative outcomes, and oncologic safety of laparoscopic surgery in patients with type II EC. Methods: A retrospective study with histologically confirmed serous or clear-cell EC without peritoneal carcinomatosis treated by laparoscopy (G1) or laparotomy (G2) was conducted. Procedures included hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and pelvic and para-aortic lymphadenectomy. Results: From 2009 to 2015, 89 patients were included; 53 women underwent laparoscopy and 36 underwent laparotomy. No relevant epidemiological or oncologic difference between groups was observed. The mean number of removed pelvic nodes was 16 [ 10] and 12 [ 13] in group 1 (G1) and group 2 (G2), respectively (P = 0.127). The mean number of dissected para-aortic nodes was significantly greater in the laparoscopic group (11 [ 9] vs 6 [ 9], P = 0.006). Para-aortic metastasis was significantly more often observed in the endoscopy group (26% vs 13%, P = 0.04). Adjuvant therapies were given to 86% of the patients in the study and 75% in the control group (P = 0.157). No excessive blood loss, casualty related to surgery, intraoperative complication, or conversion to laparotomy occurred in G1. Ten (18%) women from G1 and 36% (13/36) in G2 developed relevant postoperative complications (P = 0.03). The median duration of follow-up was 38 months for the laparoscopy and 47 months for the open surgery (P = 0.12). The 5-year overall and disease-free survival were similar, 86% versus 78% and 58% versus 51% for G1 and G2, respectively (P = 0.312). Conclusions: Laparoscopy is oncologically at least not inferior to laparotomy for the surgical treatment of type II EC. Endoscopic techniques are feasible, effective, result in significantly less morbidity, and improved quality staging. Although statistical significance was not reached, laparoscopy was associated with superior oncologic results.