MICHELE TATIANA PEREIRA TOMITAO

(Fonte: Lattes)
Índice h a partir de 2011
3
Lattes
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina

Filtros

Limpar filtros

Configurações

Assunto: Oncology ×

Resultados de Busca

Agora exibindo 1 - 4 de 4
  • article 3 Citação(ões) na Scopus
    Cyclooxygenase-2 gene polymorphisms and susceptibility to colorectal cancer in a Brazilian population
    (2017) TOMITAO, Michele Tatiana Pereira; NAHAS, Sergio Carlos; KUBRUSLY, Marcia Saldanha; FURUYA, Tatiane Katsue; DINIZ, Marcio Augusto; MARIE, Suely Kazue Nagahashi; SAFATLE-RIBEIRO, Adriana Vaz; ELUF-NETO, Jose; CECCONELLO, Ivan; RIBEIRO JR., Ulysses
    Background: Multi-ethnicity of Brazilian population displays high levels of genomic diversity. Polymorphism may detect people at higher risk of developing cancer, distinctive response to treatment, and prognosis. Cyclooxygenase-2 (COX-2) is induced in response to growth factors and cytokines, and is expressed in inflammatory diseases, precancerous lesions and colorectal cancer (CRC). The aim of this study was to evaluate the influence of COX-2 -1195A > G and 8473T > C polymorphisms as a risk factor of developing CRC. Methods: We evaluated COX-2 Single Nucleotide Polymorphism (SNP) of 230 CRC patients and 196 healthy controls by Real-Time Polymerase Chain Reaction. Results: Populations were in Hardy-Weinberg equilibrium (HWE), except for control group of 8473T > C SNP. The frequencies were similar in both groups for genotypes and haplotypes. There was no association between studied polymorphisms and risk of CRC. Conclusions: The gene polymorphisms studied do not participate in the genetic susceptibility to CRC in a Brazilian population.
  • conferenceObject
    Association between polymorphisms in inflammatory response related-genes and the susceptibility, progression, and prognosis of gastric cancer.
    (2018) FURUYA, Tatiane K.; JACOB, Carlos E.; TOMITAO, Michele T.; CORDOBA-CAMACHO, Lizeth C.; RAMOS, Marcus K.; ELUF-NETO, Jose; ALVES, Venancio A.; ZILBERSTEIN, Bruno; CECCONELLO, Ivan; RIBEIRO-JUNIOR, Ulysses; CHAMMAS, Roger
  • conferenceObject
    VEGF-A and Cox-2 gene polymorphisms and susceptibility to colorectal cancer in Brazilian population
    (2013) TOMITAO, Michele T. P.; KUBRUSLY, Marcia S.; COTTI, Guilherme C.; ZAIDAN, Evelise P.; SAFATLE-RIBEIRO, Adriana V.; MARIE, Suely K. N.; CECCONELLO, Ivan; NAHAS, Sergio C.; RIBEIRO, Ulysses
  • conferenceObject
    Jarid1b protects from metformin-induced chemosensitization to cisplatin through p53 downregulation in NSCLC
    (2018) TORTELLI JR., Tharcisio Citrangulo; TAMURA, Rodrigo Esaki; TOMITAO, Michele Tatiana Pereira; BUSTOS, Silvina Odete; SAITO, Renata de Freitas; LEANDRINI, Sarah Milani de Moraes; JACOMASSI, Mayara D'Aurea; RIBEIRO JR., Ulysses; STRAUSS, Bryan Erik; CHAMMAS, Roger