ERICH TALAMONI FONOFF
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Neurologia, Faculdade de Medicina - Docente
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
29 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 29
conferenceObject Force platform analysis after deep brain stimulation of peduncolopontine nucleus in progressive supranuclear palsy: Report of one case(2015) SOUZA, C. O.; BRANT, R.; PARDINI, A. L.; BOARI, D.; TEIXEIRA, L. A.; TEIXEIRA, M. J.; BARBOSA, E. R.; FONOFF, E. T.conferenceObject Non-motor symptoms in PD candidates for DBS treatment(2016) GHILARDI, M. G. dos Santos; MARTINEZ, R. C. R.; CURY, R. G.; ARANHA, J. R.; TEIXEIRA, M. J.; BARBOSA, E. R.; FONOFF, E. T.conferenceObject Subthalamic deep brain stimulation modulates small fiber-dependent sensory threshold in Parkinson's disease(2015) CURY, R. G.; GALHARDONI, R.; FONOFF, E. T.; GHILARDI, M. G. dos Santos; MYCZKOWSKI, M.; MARCOLIN, M. A.; BARBOSA, E. R.; TEIXEIRA, M. J.; ANDRADE, D. Ciampi deconferenceObject Correlation between novelty-seeking and harm-avoidance with depression and anxiety in Parkinson's disease(2012) FONOFF, F. M. C.; FONOFF, E. T.; QUARANTA, T.; BARBOSA, E. R.; TEIXEIRA, M. J.; FUENTES, D.Background: Lower novelty-seeking (NS) and higher harm-avoidance (HA) are characteristics often found in depressive patients. Depression is a comorbidity often found in PD patients. However, recent studies debate whether depressive-like personality traits in PD patients result from dopaminergic degeneration or are related to depression symptoms present in PD. Methods: 61 advanced PD patients and 42 healthy volunteers (HV) were submitted to personality assessment through Temperament and Character Inventory by Cloninger and to depressive and anxiety symptoms assessment through Hamilton Scales for Anxiety (Ham-A) and Depression (Ham-D). Results: PD group showed NS1 significantly lower 4,96 (SD: 2,05) and higher HA4 4,96 (SD: 1,72) than HV. However, PD group and HV did not differ significantly in Anxiety and Depression scores. Conclusions: The present data suggest that depression is not responsible for depressive-like features in PD. Following this reasoning, we can state that these personality traits can be understood independently and, therefore, as part of the motor treatment of the PD patients, a clinical follow-up of the personality traits is necessary. Further studies should investigate those personality traits in PD patients after DBS.- Restless legs syndrome in Wilson's disease: frequency, characteristics, and mimics(2017) TRINDADE, M. C.; BITTENCOURT, T.; LORENZI-FILHO, G.; ALVES, R. C.; ANDRADE, D. C. de; FONOFF, E. T.; BOR-SENG-SHU, E.; MACHADO, A. A.; TEIXEIRA, M. J.; BARBOSA, E. R.; TRIBL, G. G.ObjectiveTo determine characteristics, clinical significance, frequency, and mimics of restless legs syndrome (RLS) in a cohort of Wilson's disease (WD, n = 42/f = 18), compared to healthy, matched controls. Materials and methodsStructured clinical interviews (patients and caregiving family members), repeated neurological examinations (afternoon and presleep), comprehensive laboratory tests, WD-, RLS-, and sleep-specific rating scales, and video-polysomnography. ResultsThirteen patients with WD (13/42 = 31.0%) clearly fulfilled the five diagnostic criteria of RLS; in eight patients (19.1%), the burden of RLS was clinically significant. The RLS was of moderate severity, equally distributed among sexes, manifested mainly in the evening and before falling asleep, and had developed mostly after clinical manifestation of WD (time elapsed 10.2 14.5 years), still at a young mean age (27.5 +/- 11.5 years). The known RLS-associated features were absent (normal iron and kidney parameters) or rare (positive family history, polyneuropathy). Compared to WD patients without RLS, patients with RLS were significantly elder and had suffered longer from WD. WD-specific RLS mimics as well as RLS confounding motor comorbidities (dystonia, tremor, chorea) were frequent and a diagnostic challenge; in difficult cases, the differentiation was reached by clinical observation of the motor behavior in the evening or at nighttime. ConclusionRLS was frequent in this cohort of WD and might be causally related to WD. RLS should be included in the diagnostic work-up of WD. In complex motor disorders, differential diagnosis of RLS might require evening/nighttime examination and video-polysomnography. In WD patients with a clinically significant RLS, treatment with dopaminergic substances may be considered.
conferenceObject Spinal cord stimulation improves freezing of gait in Parkinson's disease in chronic implanted stn-dbs patients: A case report(2016) SOUZA, C. O.; SOUZA, C. P.; PARDINI, A. L.; BOARI, D.; TEIXEIRA, L. A.; BARBOSA, E. R.; FONOFF, E. T.conferenceObject Pallidal versus subthalamic stimulation for PD: Beyond the motor effects(2016) GHILARDI, M. G. dos Santos; CURY, R. G.; MARTINEZ, R. C. R.; TEIXEIRA, M. J.; BARBOSA, E. R.; FONOFF, E. T.conferenceObject Effects of STN versus GPi deep brain stimulation on impulse control disorders(2015) GHILARDI, M. G. dos Santos; COUTINHO, A. M. N.; CURY, R. G.; BARBOSA, E. R.; TEIXEIRA, M. J.; ETCHEBEHERE, E.; FONOFF, E. T.conferenceObject Correlation between pain, other non-motor symptoms, quality of life and motor improvement in patients with Parkinson's disease after deep brain stimulation(2014) CURY, R. G.; GHILARDI, M. G.; GALHARDONI, R.; SOUZA, C.; FONOFF, F.; MARCOLIN, M. A.; MYCZKOWSKI, M. L.; TEIXEIRA, M. J.; BARBOSA, E. R.; FONOFF, E. T.; ANDRADE, D. Ciampi deconferenceObject Stimulation of electrode contacts within zona incerta directly blocks levodopa-induced dyskinesias in PD patients(2013) SOUZA, C. P.; GHILARDI, M. G. S.; CURY, R. G.; RODRIGUES, R. B. M.; BARBOSA, E. R.; TEIXEIRA, M. J.; FONOFF, E. T.
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