MARIA CRISTINA CHAVANTES
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conferenceObject LASER THERAPY: AN ADJUVANT TREATMENT IN ACUTE AND CHRONIC WOUNDS REPAIRING(2013) BAPTISTA, Ivany; CHAVANTES, Maria Cristina; PINTO, Nathali; MONETTA, LinaconferenceObject LOW LEVEL LASER THERAPY IMPROVES CARDIOVASCULAR AUTONOMIC ACTIVITY IN SPONTANEOUSLY HYPERTENSIVE RATS(2015) SILVA, Bianca; TOMIMURA, Suely; SANCHES, Iris; CANAL, Marina; PINTO, Nathali; MADI, Otavio; CONTI, Felipe; ANGELIS, Katia De; COLOMBO, Fernanda; CHAVANTES, M. CristinaconferenceObject LOWLEVEL LASER THERAPY CAN IMPROVE THE THYROID VASCULARIZATION IN PATIENTS WITH CHRONIC AUTOIMMUNE THROIDITIS(2012) HOEFLING, Danilo; CHAVANTES, Maria Cristina; JULIANO, Adriana; CERRI, Giovanni; KNOBEL, Meyer; YOSHIMURA, Elisabeth; CHAMMAS, Maria CristinaBackground: Chronic autoimmune thyroiditis (CAT) frequently alters thyroid vascularization, likely as a result of the autoimmune process. Therefore, the objective of this study was to evaluate the effects of low-level laser therapy (LLLT) on the thyroid vascularization of patients with hypothyroidism induced by CAT using color Doppler ultrasound parameters. Study: A randomized clinical trial was conducted from 2006 to 2009 at the Hospital das Clínicas, University of Sao Paulo Medical School. Forty-three patients who underwent levothyroxine replacement for CAT-induced hypothyroidism were randomly assigned to receive either 10 sessions of LLLT (L group, n=23) or 10 sessions of a placebo treatment (P group, n=20). Color Doppler ultrasounds were performed before and 30 days after the end of the interventions. All of the patients in both groups continued taking their previous levothyroxine doses for the duration of the study. To verify the vascularization of the thyroid parenchyma, power Doppler was performed. The systolic peak velocity (SPV) and resistance index (RI) in the superior and inferior thyroid arteries were measured by pulsed Doppler. Results: All of the patients completed the study. The frequency of normal vascularization of the thyroid lobes observed in the post-intervention power Doppler examination was significantly higher in the L than in the P group (P=0.023). The pulsed Doppler examination revealed an increase in the SPV of the inferior thyroid arteries in the L group compared with the P group (P=0.016), whereas no significant difference in the SPV of the superior thyroid arteries was found between the groups. There was also no significant difference in the RI between the groups. Conclusion: These results suggest that LLLT can ameliorate thyroid parenchyma vascularization and increase the SPV of the inferior thyroid arteries of patients with hypothyroidism caused by CAT.conferenceObject ANALYSIS OF OPTICAL DOSIMETRY IN RAT-TAIL MAY CORROBORATE TRANSCUTANEOUS LOW-LEVEL LASER THERAPY IN BLOOD RESPONSE(2013) SOUSA, Marcelo; PINTO, Nathali; YOSHIMURA, Elisabeth; CANAL, Marina; NAKATA, Leticia; PEREIRA, Mara; MARTINS, Luis; CHAVANTES, Maria CristinaconferenceObject LONG-TERM FOLLOW-UP OF PATIENTS WITH HYPOTHYROIDISM INDUCED BY AUTOIMMUNE THYROIDITIS SUBMITTED TO LOW-LEVEL LASER THERAPY(2017) HOFLING, Danilo; CHAVANTES, M. Cristina; BUCHPIGUEL, Carlos Alberto; CERRI, Giovanni Guido; CARNEIRO, Paulo Campos; MARUI, Suemi; CHAMMAS, Maria CristinaconferenceObject HEMODYNAMIC CHANGES POST LOW LEVEL LASER THERAPY IN ELDERLY OBESE RATS: AN EXPERIMENTAL STUDY(2013) CANAL, Marina; CONTI, Filipe; PINTO, Nathali; PINTO, Michael; SILVA, Bianca; SANCHES, Iris; DUARTE, Ivone; ANGELIS, Katia De; CONSOLIM-COLOMBO, Fernanda; CHAVANTES, Maria Cristina- Hemodynamic Effect of Laser Therapy in Spontaneously Hypertensive Rats(2014) TOMIMURA, Suely; SILVA, Bianca Passos Assumpcao; SANCHES, Iris Callado; CANAL, Marina; CONSOLIM-COLOMBO, Fernanda; CONTI, Felipe Fernandes; ANGELIS, Katia De; CHAVANTES, Maria CristinaSystemic arterial hypertension (SAH) is considered to be the greatest risk factor for the development of neuro-cardiovascular pathologies, thus constituting a severe Public Health issue in the world. The Low-Level Laser Therapy (LLLT), or laser therapy, activates components of the cellular structure, therefore converting luminous energy into photochemical energy and leading to biophysical and biochemical reactions in the mitochondrial respiratory chain. The LLLT promotes cellular and tissue photobiomodulation by means of changes in metabolism, leading to molecular, cellular and systemic changes. The objective of this study was to analyze the action of low-level laser in the hemodynamic modulation of spontaneously hypertensive rats, in the long term. Animals (n = 16) were randomly divided into the Laser Group (n = 8), which received three weekly LLLT irradiations for seven weeks, and into the Sham Group (n = 8), which received three weekly simulations of laser for seven weeks, accounting for 21 applications in each group. After seven weeks, animals were cannulated by the implantation of a catheter in the left carotid artery. On the following day, the systemic arterial pressure was recorded. The Laser Group showed reduced levels of mean blood pressure, with statistically significant reduction (169 +/- 4 mmHg* vs. 182 +/- 4 mmHg from the Sham Group) and reduced levels of diastolic pressure (143 +/- 4 mmHg* vs. 157 +/- 3 mmHg from the Sham Group), revealing a 13 and 14 mmHg decrease, respectively. Besides, there was a concomitant important decline in heart rate (312 +/- 14 bpm vs. 361 +/- 13 bpm from the Sham Group). Therefore, laser therapy was able to produce hemodynamic changes, thus reducing pressure levels in spontaneously hypertensive rats.
conferenceObject LOW LEVEL LASER THERAPY'S EFFECT RELATING TO THE ELECTROMYOGRAPHIC ACTIVITY AND THE POSTURE IN THE TEMPOROMANDIBULARS DISORDERS: PILOT STUDY(2012) SERRAO, Nelson; MARTINICHEN, Marcia; MAGNANI, Rina; PINTO, Nathali; CHAVANTES, Maria Cristina- The use of a high-power laser on swine mitral valve chordae tendineae(2016) PINTO, Nathali Cordeiro; CHAVANTES, M. Cristina; ZEZELL, Denise; DEANA, Alessandro; BENETTI, Carolina; MARCOS, Rodrigo Labat; LOPES, Luciana Almeida; MARTINS, Rodrigo A. B. Lopes; AIELLO, Vera Demarchi; JATENE, Fabio Biscegli; POMERANTZEFF, Pablo M. A.Worldwide, rheumatic fever remains a significant cause of mitral valve insufficiency. It is responsible for approximately 90 % of early childhood valvular surgeries in Brazil. Elongated or flail chordae are frequently responsible and require surgical correction. The purpose of this study was to analyze and compare the histological tissues of the mitral valve chordae and the mechanical resistance generated by the chordae, both with and without the application of a high-power laser. Twenty normal porcine mitral valve chordae were measured and divided randomly into the following two groups: control group (not subjected to a high-power laser) and laser group (subjected to photonic irradiation). Laser surgery was performed under controlled conditions, using following parameters: lambda = 980-nm wavelength, power = 3 W, and energy = 60 J. A mechanical test machine was used in combination with a subsequent histological study to measure chordae tensile properties. A histological analysis demonstrated a typical collagen bundle arrangement in the control group; however, under a particular reached temperature range (48), the collagen bundles assumed different arrangements in the laser group. Significant reductions in the chordae tendineae lengths and changes in their resistance in the laser group were observed, as these chordae exhibited less rigid fibers. The chordae tendineae of normal porcine valves subjected to a high-power laser exhibited its length reduction and less stiffness compared to the control group. A histological analysis of the laser treatment specimens demonstrated differences in collagen bundle spatial organization, following slight changes into tissue temperature.
- Photobiomodulation of the dorsal root ganglion for the treatment of low back pain: A pilot study(2016) HOLANDA, Vanessa Milanesi; CHAVANTES, Maria Cristina; SILVA, Daniela Fatima Teixeira; HOLANDA, Carlos Vanderlei M. de; OLIVEIRA JR., Jose Oswaldo de; WU, Xingjia; ANDERS, Juanita J.Background and ObjectiveChronic low back pain is a worldwide public health issue with high socioeconomic impact. The aim of this study was to determine the efficacy of laser irradiation of the dorsal root ganglion of the second lumbar spinal nerve for chronic axial low back pain compared to lidocaine injection and radiofrequency treatment. Study Design/Materials and MethodsTwenty-eight patients were randomly divided into three treatment groups: lidocaine injection, radiofrequency, or laser. The second intervertebral foramen between the second and third lumbar vertebrae was accessed by percutaneous needle puncture bilaterally, guided by fluoroscopy. In the local anesthetic group, injection of 1ml lidocaine without epinephrine was applied through a 20-gauge (G20) Quincke tip spinal needle inserted in the second lumbar intervertebral foramen. In the radiofrequency group, the probe (150mm long with a 5mm active tip) was directed through a G20 needle placed in the second lumbar intervertebral foramen and neuromodulation was done with a radiofrequency of Cosman G4 (R) in pulses of 20ms with wash-out period of 480ms, for 300seconds at 42 degrees C. A single treatment was used. In the laser treatment group, a continuous wave, 808nm wavelength diode laser (Photon Lase III (R) DCM, Brazil), with an output power of 100mW was used for a single treatment. An 18 gauge needle was placed in the second lumbar intervertebral foramen guided by fluoroscopy. Light was delivered through a 600 mu m optical fiber placed in the G18 needle. The tip of the fiber extended 5mm beyond the tip of the needle in the second lumbar intervertebral foramen. The beam spot size was 0.003cm(2), irradiance=35W/cm(2), exposure time=84seconds, energy density=2800J/cm(2), total energy was 8.4J. The low back pain score was assessed by the visual analog scale (VAS) and Pain Relief Scale (PRS) pre, post procedure and in 1 month follow up. Temperature was measured using a digital thermometer. ResultsAll patients in the local anesthetic and laser treatment groups reported a pain reduction of at least 50% immediately post-procedure and 10 out of 11 patients in the radiofrequency group reported a pain reduction of at least 50%. At 1 month post-treatment, the laser treatment group had the greatest number of patients who reported more than 50% pain relief based on PRS (7 out of 10 patients) while only 2 out of 7 patients and 3 out of 11 patients in the lidocaine and radiofrequency treatment groups respectively reported more than a 50% pain relief. ConclusionLaser irradiation caused an immediate decrease in low back pain post-procedure similar to pain reduction caused by lidocaine injection. Both lidocaine injection and laser irradiation were more effective than radiofrequency treatment for immediate and longer term (1 month post-treatment) chronic back pain. Lasers Surg. Med. 48:653-659, 2016. (c) 2016 Wiley Periodicals, Inc.