ANA CRISTINA DE MEDEIROS RIBEIRO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
conferenceObject INFLUENCE OF SULFASALAZINE COMEDICATION IN SWITCHING AND RESPONSE TO ANTI-TUMORAL NECROSIS FACTOR IN ANKYLOSING SPONDYLITIS(2016) SHIMABUCO, A. Y.; GONCALVES, C. R.; MORAES, J. C. B.; WAISBERG, M. G.; RIBEIRO, A. C. M.; SAMPAIO-BARROS, P. D.; GOLDENSTEIN-SCHAINBERG, C.; BONFA, E.; SAAD, C. G. S.- Systemic and localized infection by Candida species in patients with rheumatic diseases receiving anti-TNF therapy(2016) AIKAWA, Nadia E.; ROSA, Daniela T. A.; NEGRO, Gilda M. B. Del; MORAES, Julio C. B.; RIBEIRO, Ana C. M.; SAAD, Carla Goncalves; SILVA, Clovis A.; BONFA, EloisaObjective: To evaluate the prevalence of systemic and localized infection by Candida species and its possible association with demographic, clinical and laboratory manifestations and therapy in patients with rheumatic diseases taking TNF blockers. Methods: Consecutive patients with rheumatic diseases receiving anti-TNF agents were included. The following risk factors up to four weeks prior to the study were analyzed: use of antibiotics, immunosuppressant drugs, hospitalization and invasive procedures. All subjects were evaluated for clinical complaints; specific blood cultures were obtained for fungi and blood samples were collected for Candida spp. detection by polymerase chain reaction. Results: 194 patients [67 with rheumatoid arthritis (RA), 47 with ankylosing spondylitis (AS), 36 with juvenile idiopathic arthritis (JIA), 28 with psoriatic arthritis and 16 with other conditions] were included. The average age of patients was 42 +/- 16 years, with 68 (35%) male and mean disease duration of 15 +/- 10 years. Sixty-four (33%) patients were receiving adalimumab, 59 (30%) etanercept and 71 (36%) infliximab. Eighty-one percent of patients were concomitantly taking immunosuppressant drugs. At the time of the study, only one (0.5%) patient had localized fungal infection (vaginal candidiasis). None of the patients included had systemic candidiasis with positive blood cultures for fungi or IDCR positive for Candida spp. in peripheral blood sample. Conclusions: This was the first study to assess the prevalence of invasive and localized fungal disease by Candida in a significant number of patients with rheumatic diseases on anti-TNF therapy, and demonstrated low risk of candidiasis, despite the high prevalence of immunosuppressive drug use. (C) 2015 Elsevier Editora Ltda.
conferenceObject LATENT TUBERCULOSIS SCREENING AND TREATMENT IN ANKYLOSING SPONDYLITIS PATIENTS UNDER ANTI-TNF THERAPY IN ENDEMIC AREA(2016) MORAES, J. C. B.; SAAD, C. G. S.; MIOSSI, R.; BONFIGLIOLI, K. R.; RIBEIRO, A. C. M.; BONFA, E.bookPart Manifestações Reumatológicas das Doenças Sistêmicas(2016) RIBEIRO, Ana Cristina de Medeiros; CALICH, Ana Luisa GarciaconferenceObject Changes on Body Composition in Women with Long-Standing Established Rheumatoid Arthritis: Differences By Level of Disease Activity(2016) CARVALHO, Gabriela Daffre; BONFIGLIOLI, Karina; RIBEIRO, Ana C. M.; GONCALVES, Celio R.; PEREIRA, Rosa M. R.; DOMICIANO, Diogo S.bookPart Artrite Reumatoide(2016) MEDEIROS, Ana Cristina de; DOMICIANO, Diogo; LAURINDO, Iêda Maria Magalhães; BONFIGLIOLI, Karina RossiconferenceObject Early DAS28 Drop Is a Predictor for Clinical Response to Anti-TNF Agents in Patients with Rheumatoid Arthritis: An Observational Study of a Real Life Inception Cohort(2016) RIBEIRO, Ana C. M.; BONFIGLIOLI, Karin.; MIOSSI, Renata; SAAD, Carla G. S.; MORAES, Julio C. B.; WAISBERG, Mariana G.; SOUZA, Fernando Henrique Carlos de; AIKAWA, Nadia E.; PRADO, Leandro L. do; LOPES, Michelle; SEGURO, Luciana; BONFA, Eloisa