LUANA FARIAS DE OLIVEIRA
Projetos de Pesquisa
Unidades Organizacionais
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
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conferenceObject Beta-Alanine Did Not Improve High-Intensity Performance Throughout Simulated Road Cycling(2021) PERIM, Pedro; GOBBI, Nathan; DUARTE, Breno; OLIVEIRA, Luana Faria de; COSTA, Luiz Augusto Riani; SALE, Craig; GUALANO, Bruno; DOLAN, Eimear; SAUNDERS, Bryan- Beta-alanine did not improve high-intensity performance throughout simulated road cycling(2022) PERIM, Pedro; GOBBI, Nathan; DUARTE, Breno; OLIVEIRA, Luana Farias de; COSTA, Luiz Augusto Riani; SALE, Craig; GUALANO, Bruno; DOLAN, Eimear; SAUNDERS, BryanThis study investigated the effect of beta-alanine supplementation on short-duration sprints and final 4-km simulated uphill cycling time-trial performance during a comprehensive and novel exercise protocol representative of the demands of road-race cycling, and determined if changes were related to increases in muscle carnosine content. Seventeen cyclists (age 38 +/- 9 y, height 1.76 +/- 0.07 m, body mass 71.4 +/- 8.8 kg, V?O-2max 52.4 +/- 8.3 ml center dot kg(-1)center dot min(-1)) participated in this placebo-controlled, double-blind study. Cyclists undertook a prolonged intermittent cycling protocol lasting 125 min, with a 10-s sprint every 20 min, finishing with a 4-km time-trial at 5% simulated incline. Participants completed two familiarization sessions, and two main sessions, one pre-supplementation and one post-supplementation following 28 days of 6.4 g center dot day(-1) of beta-alanine (N=11) or placebo (N=6; maltodextrin). Muscle biopsies obtained pre- and post-supplementation were analysed for muscle carnosine content. There were no main effects on sprint performance throughout the intermittent cycling test (all P>0.05). There was no group (P=0.69), time (P=0.50) or group x time interaction (P=0.26) on time-to-complete the 4-km time-trial. Time-to-completion did not change from pre- to post-supplementation for BA (-19.2 +/- 45.6 s, P=0.43) or PL (+2.8 +/- 31.6 s, P=0.99). Beta-alanine supplementation increased muscle carnosine content from pre- to post-supplementation (+9.4 +/- 4.0 mmol center dot kg(-1)dm; P<0.0001) but was not related to performance changes (r=0.320, P=0.37). Chronic beta-alanine supplementation increased muscle carnosine content but did not improve short-duration sprint performance throughout simulated road race cycling, nor 4-km uphill time-trial performance conducted at the end of this cycling test.