MAURA SALAROLI DE OLIVEIRA
Projetos de Pesquisa
Unidades Organizacionais
PAHC, Hospital das Clínicas, Faculdade de Medicina
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina
LIM/49 - Laboratório de Protozoologia, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- Current Status of Antimicrobial Stewardship Programs in Sao Paulo Hospitals(2020) SATO, Silvia; MADALOSSO, Geraldine; ASSIS, Denise; PERDIGAO-NETO, Lauro; LEVIN, Anna; OLIVEIRA, Maura
- Implementation of tailored interventions in a statewide programme to reduce central line-associated bloodstream infections(2018) ASSIS, D. B.; MADALOSSO, G.; PADOVEZE, M. C.; LOBO, R. D.; OLIVEIRA, M. S.; BOSZCZOWSKI, I; SINGER, J. M.; LEVIN, A. S.Background: There have been few studies exploring implementation strategies to central line-associated bloodstream infections (CLABSIs) in low- or middle-income countries. Aim: To implement tailored interventions to reduce CLABSI rates in adult intensive care units. Methods: The implementation strategy of the State Health Department was performed in Sao Paulo State, Brazil, over two cycles. Cycle 1 (56 hospitals) was exploratory and cycle 2 (77 hospitals) was designed to confirm the hypothesis generated by the first cycle, with three phases each (pre-intervention, intervention, post-intervention). Cycles included: evaluation of healthcare workers' knowledge, observation of practices, and CLABSI rates monthly report. In cycle 1, a log-normal mixed model was used to select variables significantly associated with the reduction of CLABSI. In cycle 2, CLABSI rates were evaluated. Findings: Healthcare workers' practices improved after intervention. In cycle 1, reduction of CLABSI rates was more pronounced in hospitals with initial CLABSI rates >7.4 per 1000 catheter-days (P < 0.001) and those that introduced the use of peripherally inserted central catheters (P= 0.01). For hospitals with high CLABSI initial rates, simulation demonstrated that the rates were expected to decrease by 36% (95% CI: 9-63), no matter the type of intervention. In cycle 2, there was an overall decrease in CLABSI rates during the intervention period; whereas the mean rate fell further post-intervention, rates at the 90th percentile increased. Conclusion: The implementation strategy may have had an effect on infection rates independently of the specific interventions implemented; however, the sustainability of reduction in the post-intervention period remains a challenge.
- Nationwide surveillance system to evaluate hospital-acquired COVID-19 in Brazilian hospitals(2022) COSTA, M. Machado de Miranda; GUEDES, A. R.; NOGUEIRA, M. D. S. P.; OLIVEIRA, L. S. C.; BARROS, L. de Souza; GONCALVES, M. R. S.; CARVALHO, A. A.; MOURA, H. L. C. Amaral de; LEVIN, A. S.; OLIVEIRA, M. S.Background: Although the risk of SARS-CoV-2 transmission within hospitals has been well recognized, there is a paucity of data on its occurrence. Our aim was to report the incidence of hospital-acquired (HA) COVID-19 at Brazilian hospitals. Methods: We investigated the incidence of HA COVID-19 in Brazilian hospitals using data from a national surveillance system, from August 2020 through September 2021. Definitions of HA COVID-19 were: (1) symptom onset >14 days after hospital admission plus a positive SARS-CoV-2 RNA or antigen test; (2) symptom onset on days 8-14 after admission, plus a positive SARS-CoV-2 RNA or antigen test positive, plus documented high-risk exposure. We performed descriptive analyses and reported HA COVID-19 rates using pooled mean and percentile distribution. Results: A total of 48,634 cases of HA COVID-19 were reported from 1428 hospitals. Incidence ranged from 0.16/1000 patient-days at neonatal intensive care units (ICUs) to 5.8/1000 patient-days at adult ICUs. The highest incidence of HA COVID-19 was during the months March to July 2021, similar to that which was observed for community-acquired COVID-19. Conclusions: This report provides a national view of the burden of HA COVID-19. The highest incidence of HA COVID-19 similar that which was observed for community-acquired COVID-19. We believe that this reflects the difficulty of implementing preventive measures. Further studies evaluating risk factors for the hospital transmission of SARS-Cov-2 should clarify strategies to minimize the risk of HA COVID-19 and may be applicable to other respiratory diseases. Furthermore, the implementation of a national system to evaluate HA COVID-19 has the potential to shine a light on this problem and lead to interventions in each hospital.
- SARS-Cov-2 seroprevalence and risk factors among health care workers: Estimating the risk of COVID-19 dedicated units(2021) OLIVEIRA, Maura Salaroli de; LOBO, Renata Desordi; DETTA, Felippe Pires; VIEIRA-JUNIOR, Mauro; CASTRO, Thiago Lucas de Souza; ZAMBELLI, Daniella Bosco; CARDOSO, Luiz Francisco; BORGES, Igor Carmo; TOZETTO-MENDOZA, Tania Regina; COSTA, Silvia Figueiredo; MENDES-CORREA, Maria CassiaWe evaluated the seroprevalence of SARS-CoV-2 and risk factors among 1,996 oligo/asymptomatic health care workers. The seroprevalence was 5.5% and risk factors associated with being infected with SARS-CoV-2 was professional category of cleaning (adj odds ratio 2.22, 95% confidence interval: 1.12-4.44, P: .023) and male gender (adj odds ratio: 1.54, 95% confidence interval: 1.03-2.32, P:.035).Working at dedicated COVID-19 units (high-risk group) was not an independent risk factor for seropositivity.
- A Successful Bundled Intervention to Reduce Hospital-Acquired Pneumonia: Sustainability Still an Issue(2020) BEN, Mirian Dal; PERDIZ, Rafael; AMARANTE, Gustavo; COLOMBARI, Heloise; RAMOS, Cintia; VIVEIROS, Libanes Viviane; BARBOSA, Sandra; OLIVEIRA, Maura
- Hospital-Acquired Vector-Transmitted Dengue Fever: An Overlooked Problem?(2016) ALMEIDA-NUNES, Juliana; MARCILIO, Izabel; OLIVEIRA, Maura S.; GONCALVES, Elenice M. N.; BATISTA, Marjorie V.; MENDRONE JR., Alfredo; LEVI, Jose E.; COSTA, Silvia F.; LEVIN, Anna S.
- Evaluating the Cost-Effectiveness of Proposed Algorithms for C. difficile Infection in Different Pretest Probability Settings(2020) BEN, Mirian Dal; OLIVEIRA, Maura; CAPPELLANO, Paola; FLEURY, Grupo; SAMPAIO, Jorge; FLEURY, Grupo; DIAS, Maria Beatriz