RODRIGO RUANO
Projetos de Pesquisa
Unidades Organizacionais
LIM/57 - Laboratório de Fisiologia Obstétrica, Hospital das Clínicas, Faculdade de Medicina
17 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 17
bookPart Diagnóstico de gravidez(2013) CHAU, Juang Horng; RUANO, Rodrigo; ZUGAIB, MarceloconferenceObject Estimating risk factors for spontaneous preterm delivery in teen pregnancies(2013) BAKER, Arthur; RUANO, Rodrigo; HAERI, Sina- Reference Range for Fetal Interventricular Septum Area by Means of Four-Dimensional Ultrasonography Using Spatiotemporal Image Correlation(2013) NARDOZZA, Luciano Marcondes Machado; ROLO, Liliam Cristine; ARAUJO JUNIOR, Edward; HATANAKA, Alan Roberto; ROCHA, Luciane Alves; SIMIONI, Christiane; RUANO, Rodrigo; MORON, Antonio FernandesObjective: To determine reference range for fetal interventricular septum area by means of 3-dimensional ultrasonography (3DUS) using the spatiotemporal image correlation (STIC) method. Methods: A prospective, cross-sectional study was conducted on 328 normal pregnant women between the 18th and 33rd gestational weeks. To obtain the interventricular septum area, a virtual plane was used, with the green line (region of interest) adjacent to the external margin of the septum, which was manually delimited. To evaluate the correlation of the septum area with the gestational age, different regression modes were evaluated. The intraclass correlation coefficient was used to evaluate the interobserver reproducibility. Results: The interventricular septum area showed correlation with the gestational age (r = 0.81). The mean increased from 0.47 +/- 0.10 cm(2) in the 18th week to 2.42 +/- 1.13 cm(2) in the 33rd week of gestation. The mathematical equation that best represented this correlation was provided by linear regression: interventricular septum area = 0.0511 x gestational age (R-2 = 0.095). The interobserver reproducibility was good, with bias of 0.01 cm(2), precision of 0.07 cm(2) and absolute limits of agreement of -0.14 and +0.15 cm(2). Conclusions: Reference range for fetal interventricular septum area were determined by means of 3DUS using STIC in the rendering mode and were shown to be reproducible:
conferenceObject Pregnant women with type 2 diabetes mellitus (DM) show evidence of altered cerebral blood hemodynamics compared to controls(2013) CHEN, Qian; HAERI, Sina; VEEN, Teelkien Van; RUANO, Rodrigo; GOLABBAKHSH, Hossein; MORALES, Yisel; HALL, Nicole; MASON, Chawla; BELFORT, Michaelarticle 13 Citação(ões) na Scopus Renal Volumes Measured by 3-Dimensional Sonography in Healthy Fetuses From 20 to 40 Weeks(2013) YOSHIZAKI, Carlos Tadashi; FRANCISCO, Rossana P. V.; PINHO, Joao Correia de; RUANO, Rodrigo; ZUGAIB, MarceloObjectives-The purpose of this study was to establish reference values for fetal kidney volumes as a function of gestational age, estimated by 3-dimensional sonography using the Virtual Organ Computer-Aided Analysis (VOCAL) technique (GE Healthcare, Kretztechnik, Zipf, Austria). Methods-Volumes of right and left kidneys were assessed in 213 healthy fetuses by 3-dimensional sonography using the VOCAL technique. Inclusion criteria were healthy women with singleton pregnancies, unremarkable comprehensive fetal sonographic findings, well-known gestational age established by first-trimester sonography, and gestational ages between 20 and 40 weeks. Exclusion criteria were patients lost to follow-up and birth weight abnormalities. Each patient was scanned once during pregnancy. Regression analysis was used to calculate unified formulas. Results-The mathematical models calculated in the study were as follows: expected right kidney volume = exp[-1.01 + (0.12 x gestational age)]; and expected left kidney volume = exp[-0.90 + (0.12 x gestational age)]. No significant intraobserver or inter-observer variability was observed for the determined volumes. Conclusions-Reference values for right and left fetal kidney volumes throughout gestation using the rotational technique (VOCAL) are described. The use of this technique might aid in further definition of gestational age kidney volume standards to help in defining variations from the norm.bookPart Mastite Puerperal(2013) YOSHIZAKI, Carlos Tadashi; RUANO, Rodrigo; ZUGAIB, MarceloconferenceObject Estimation of maternal cerebrovascular hemodynamics following routine delivery related blood loss(2013) HALL, Nicole; HAERI, Sina; RUANO, Rodrigo; VEEN, Teelkien Van; GOLABBAKHSH, Hossein; CHEN, Qian; MORALES, Yisel; MASON, Chawla; BELFORT, MichaelconferenceObject Maternal obesity is associated with increased cerebral perfusion pressure in pregnancy(2013) HAERI, Sina; RUANO, Rodrigo; GOLABBAKHSH, Hossein; CHEN, Qian; VEEN, Teelkien Van; MORALES, Yisel; HALL, Nicole; MASON, Chawla; BELFORT, Michael- Early fetoscopic tracheal occlusion for extremely severe pulmonary hypoplasia in isolated congenital diaphragmatic hernia: preliminary results(2013) RUANO, R.; PEIRO, J. L.; SILVA, M. M. da; CAMPOS, J. A. D. B.; CARRERAS, E.; TANNURI, U.; ZUGAIB, M.Objective To evaluate the effect of early fetoscopic tracheal occlusion (FETO) (22-24 weeks' gestation) on pulmonary response and neonatal survival in cases of extremely severe isolated congenital diaphragmatic hernia (CDH). Methods This was a multicenter study involving fetuses with extremely severe CDH (lung-to-head ratio < 0.70, liver herniation into the thoracic cavity and no other detectable anomalies). Between August 2010 and December 2011, eight fetuses underwent early FETO. Data were compared with nine fetuses that underwent standard FETO and 10 without fetoscopic procedure from January 2006 to July 2010. FETO was performed under maternal epidural anesthesia, supplemented with fetal intramuscular anesthesia. Fetal lung size and vascularity were evaluated by ultrasound before and every 2 weeks after FETO. Postnatal therapy was equivalent for both treated fetuses and controls. Primary outcome was infant survival to 180 days and secondary outcome was fetal pulmonary response. Results Maternal and fetal demographic characteristics and obstetric complications were similar in the three groups (P > 0.05). Infant survival rate was significantly higher in the early FETO group (62.5%) compared with the standard group (11.1%) and with controls (0%) (P < 0.01). Early FETO resulted in a significant improvement in fetal lung size and pulmonary vascularity when compared with standard FETO (P < 0.01). Conclusions Early FETO may improve infant survival by further increases of lung size and pulmonary vascularity in cases with extremely severe pulmonary hypoplasia in isolated CDH. This study supports formal testing of the hypothesis with a randomized controlled trial.
- Fetoscopic laser ablation of placental anastomoses in twin-twin transfusion syndrome using 'Solomon technique'(2013) RUANO, R.; RODO, C.; PEIRO, J. L.; SHAMSHIRSAZ, A. A.; HAERI, S.; NOMURA, M. L.; SALUSTIANO, E. M. A.; ANDRADE, K. K. de; SANGI-HAGHPEYKAR, H.; CARRERAS, E.; BELFORT, M. A.ObjectiveTo document perinatal outcomes following use of the Solomon technique' in the selective photocoagulation of placental anastomoses for severe twin-twin transfusion syndrome (TTTS). MethodsBetween January 2010 and July 2012, data were collected from 102 consecutive monochorionic twin pregnancies complicated by severe TTTS that underwent fetoscopic laser ablation at four different centers. We compared outcomes between subjects that underwent selective laser coagulation using the Solomon technique (cases) and those that underwent selective laser coagulation without this procedure (controls). ResultsOf the 102 pregnancies examined, 26 (25.5%) underwent the Solomon technique and 76 (74.5%) did not. Of the 204 fetuses, 139 (68.1%) survived up to 30 days of age. At least one twin survived in 82 (80.4%) pregnancies and both twins survived in 57 (55.9%) pregnancies. When compared with the control group, the Solomon-technique group had a significantly higher survival rate for both twins (84.6 vs 46.1%; P < 0.01) and a higher overall neonatal survival rate (45/52 (86.5%) vs 94/152 (61.8%); P < 0.01). Use of the Solomon technique remained independently associated with dual twin survival (adjusted odds ratio (aOR), 11.35 (95% CI, 3.11-53.14); P = 0.0007) and overall neonatal survival rate (aOR, 4.65 (95% CI, 1.59-13.62); P = 0.005) on multivariable analysis. There were no cases of recurrent TTTS or twin anemia-polycythemia sequence (TAPS) in the Solomon-technique group. ConclusionsUse of the Solomon technique following selective laser coagulation of placental anastomoses appears to improve twin survival and may reduce the risk of recurrent TTTS and TAPS. Our data support the idea of performing a randomized controlled trial to evaluate the effectiveness of the Solomon technique.