PERCIVAL DEGRAVA SAMPAIO BARROS
Índice h a partir de 2011
26
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina
10 resultados
Resultados de Busca
Agora exibindo 1 - 10 de 10
- EARLY SACROILIITIS AND PROGRESSION TO ANKYLOSING SPONDYLITIS IS ASSOCIATED TO POSITIVE HLA-B27 IN JUVENILE SPONDYLOARTHRITIS(2015) PEREZ, M. O.; AIKAWA, N. E.; CARRASCO, S.; SAAD, C. G.; SAMPAIO-BARROS, P. D.; GONCALVES, C. R.; MORAES, J. C. B.; GOLDENSTEIN-SCHAINBERG, C.
- HIGH RATES OF WORK DISABILITY IN PATIENTS WITH PSORIATIC ARTHRITIS(2015) GASPARI, C. N. De; GOLDEINSTEIN-SCHAINBERG, C.; PRETTI, F. Z.; SILVA, T. C. P.; GONCALVES, C. R.; SAMPAIO-BARROS, P. D.; SAAD, C. G. S.; MORAES, J. C. B.
conferenceObject Metabolic Syndrome in Patients with Psoriatic Arthritis Is Associated to Peripheral Disease Activity(2015) GASPARI, Camilla De; MORAES, Julio C. B.; SAMPAIO-BARROS, Percival D.; GONCALVES, Celio R.; SAAD, Carla G. S.; GOLDENSTEIN-SCHAINBERG, ClaudiaconferenceObject Hand Bone Impairment By High-Resolution Peripheral Quantitative Computed Tomography in Patients with Diffuse Systemic Sclerosis: Correlation with Clinical Parameters, Quality of Life and Capillaroscopic Findings(2015) SAMPAIO-BARROS, Marilia; TAKAYAMA, Liliam; ALVARENGA, Jackeline Couto; LUPPINO-ASSAD, Ana Paula; SAMPAIO-BARROS, Percival D.; PEREIRA, Rosa M. R.bookPart Esclerose istêmica(2015) SAMPAIO-BARROS, Percival Degrava- Perfil epidemiológico da espondiloartrite de início juvenil comparada com a espondiloartrite de início na vida adulta em uma grande coorte brasileira(2015) DUARTE, Angela P.; MARQUES, Claudia D. L.; BORTOLUZZO, Adriana B.; GONCALVES, Celio R.; SILVA, Jose Antonio Braga da; XIMENES, Antonio Carlos; BERTOLO, Manoel B.; RIBEIRO, Sandra Lucia E.; KEISERMAN, Mauro; SKARE, Thelma L.; CARNEIRO, Sueli; MENIN, Rita; AZEVEDO, Valderilio F.; VIEIRA, Walber P.; ALBUQUERQUE, Elisa N.; BIANCHI, Washington A.; BONFIGLIOLI, Rubens; CAMPANHOLO, Cristiano; CARVALHO, Hellen M. S.; COSTA, Izaias P.; KOHEM, Charles L.; LEITE, Nocy; LIMA, Sonia A. L.; MEIRELLES, Eduardo S.; PEREIRA, Ivanio A.; PINHEIRO, Marcelo M.; POLITO, Elizandra; RESENDE, Gustavo G.; ROCHA, Francisco Airton C.; SANTIAGO, Mittermayer B.; SAUMA, Maria de Fatima L. C.; VALIM, Valeria; SAMPAIO-BARROS, Percival D.
- Avaliação do desempenho do BASDAI (Bath Ankylosing Spondylitis Disease Activity Index) numa coorte brasileira de 1.492 pacientes com espondiloartrites: dados do Registro Brasileiro de Espondiloartrites (RBE)(2015) COSTA, Izaias Pereira da; BORTOLUZZO, Adriana B.; GONCALVES, Celio R.; SILVA, Jose Antonio Braga da; XIMENES, Antonio Carlos; BERTOLO, Manoel B.; RIBEIRO, Sandra L. E.; KEISERMAN, Mauro; MENIN, Rita; SKARE, Thelma L.; CARNEIRO, Sueli; AZEVEDO, Valderilio F.; VIEIRA, Walber P.; ALBUQUERQUE, Elisa N.; BIANCHI, Washington A.; BONFIGLIOLI, Rubens; CAMPANHOLO, Cristiano; CARVALHO, Hellen M. S.; DUARTE, Angela L. B. Pinto; KOHEM, Charles L.; LEITE, Nocy H.; LIMA, Sonia A. L.; MEIRELLES, Eduardo S.; PEREIRA, Ivelnio A.; PINHEIRO, Marcelo M.; POLITO, Elizandra; RESENDE, Gustavo G.; ROCHA, Francisco Airton C.; SANTIAGO, Mittermayer B.; SAUMA, Maria de Fatima L. C.; VALIM, Valeria; SAMPAIO-BARROS, Percival D.Objective: To analyze the results of the application of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in a large series of Brazilian patients with the diagnosis of SpA and establish its correlations with specific variables into the group. Methods: A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyoarthropathies Study Group (ESSG), attended at 29 referral centers of Rheumatology in Brazil. Clinical and demographic variables, and disease indices (BASDAI, Basfi, Basri, Mases, ASQol) were applicated. The total values of BASDAI were compared to the presence of the different variables. Results: The mean score of BASDAI was 4.20 +/- 2.38. The mean scores of BASDAI were higher in patients with the combined (axial + peripheral + entheseal) (4.54 +/- 2.38) clinical presentation, compared to the pure axial (3.78 +/- 2.27) or pure peripheral (4.00 +/- 2.38) clinical presentations (p<0.001). BASDAI also presented higher scores associated with the female gender (p<0.001) and patients who did not practice exercises (p<0.001). Regarding the axial component, higher values of BASDAI were significantly associated with inflammatory low back pain (p<0.049), alternating buttock pain (p<0.001), cervical pain (p<0.001) and hip involvement (p< 0.001). There was also statistical association between BASDAI scores and the peripheral involvement, related to the lower (p=0.004) and upper limbs (p=0.025). The presence of enthesitis was also associated to higher scores of BASDAI (p=0.040). Positive HLA-B27 and the presence of cutaneous psoriasis, inflammatory bowel disease, uveitis and urethritis were not correlated with the mean scores of BASDAI. Lower scores of BASDAI were associated with the use of biologic agents (p<0.001). Conclusion: In this heterogeneous Brazilian series of SpA patients, BASDAI was able to demonstrate ""disease activity"" in patients with axial as well as peripheral disease.
- ALTERED SLEEP PATTERNS, FATIGUE, ANXIETY AND DEPRESSION LEVELS ARE IMPORTANT FEATURES AMONG PATIENTS WITH PSORIATIC ARTHRITIS(2015) AQUILA, L. Arancibia; MEDEIROS, A. C.; GONCALVES, C. R.; BARROS, P. D. Sampaio; SCHAINBERG, C. Goldenstein
- Safe use of biological therapies for the treatment of rheumatoid arthritis and spondyloarthritides(2015) MOTA, Licia Maria Henrique da; CRUZ, Boris Afonso; BRENOL, Claiton Viegas; POLLAK, Daniel Feldman; PINHEIRO, Geraldo da Rocha Castelar; LAURINDO, Ieda Maria Magalhaes; PEREIRA, Ivanio Alves; CARVALHO, Jozelio Freire de; BERTOLO, Manoel Barros; PINHEIRO, Marcelo de Medeiros; FREITAS, Max Victor Carioca; SILVA, Nilzio Antonio da; LOUZADA-JUNIOR, Paulo; SAMPAIO-BARROS, Percival Degrava; GIORGI, Rina Dalva Neubarth; LIMA, Rodrigo Aires Correa; ANDRADE, Luis Eduardo CoelhoThe treatment of autoimmune rheumatic diseases has gradually improved over the last half century, which has been expanded with the contribution of biological therapies or immunobiopharmaceuticals. However, we must be alert to the possibilities of undesirable effects from the use of this class of medications. The Brazilian Society of Rheumatology (Sociedade Brasileira de Reumatologia) produced a document based on a comprehensive literature review on the safety aspects of this class of drugs, specifically with regard to the treatment of rheumatoid arthritis and spondyloarthritides. The themes selected by the participating experts, on which considerations have been established as the safe use of biological drugs, were: occurrence of infections (bacterial, viral, tuberculosis), infusion reactions, hematological, neurological, gastrointestinal and cardiovascular reactions, neoplastic events (solid tumors and hematologic neoplasms), immunogenicity, other occurrences and vaccine response. For didactic reasons, we opted by elaborating a summary of safety assessment in accordance with the previous themes, by drug class/mechanism of action (tumor necrosis factor antagonists, T-cell co-stimulation blockers, B-cell depletors and interleukin-6 receptor blockers). Separately, general considerations on safety in the use of biologicals in pregnancy and lactation were proposed. This review seeks to provide a broad and balanced update of that clinical and experimental experience pooled over the last two decades of use of immunobiological drugs for RA and spondyloarthritides treatment.
conferenceObject Sulfasalazine Comedication: A Predictor of Reduced Long-Term Anti-TNF Switch in Ankylosing Spondylitis(2015) SHIMABUCO, Andrea Y.; GONCALVES, Celio R.; MORAES, Julio C. B.; WAISBERG, Mariana G.; SAMPAIO-BARROS, Percival D.; GOLDENSTEIN-SCHAINBERG, Claudia; BONFA, Eloisa; SAAD, Carla G. S.