THAIS BENTO LIMA DA SILVA
Projetos de Pesquisa
Unidades Organizacionais
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
5 resultados
Resultados de Busca
Agora exibindo 1 - 5 de 5
- Effects of cognitive interventions with video games on cognition in healthy elderly people: a systematic review(2023) ISHIBASHI, Graciela Akina; SANTOS, Gabriela dos; MOREIRA, Ana Paula Bagli; VERGA, Cassia Elisa Rossetto; SILVA, Guilherme Alves da; ORDONEZ, Tiago Nascimento; MORAES, Luiz Carlos de; LESSA, Patricia Prata; BRUCKI, Sonia Maria Dozzi; SILVA, Thais Bento Lima daBackground Currently, studies using video games as an intervention to improve cognitive functions in the elderly are on the rise.Objective To investigate and evaluate the effects of cognitive interventions using video games on cognition in healthy elderly people published in the last ten years.Methods A systematic review involving a qualitative analysis carried out between July and September 2021on the SciELO, LILACS and MEDLINE databases..Results A total of 262 articles were identified in the initial search. After exclusion of duplicates, analysis of titles/abstracts and of the full text, a final total of 9 studies were included in the review. The objectives of the studies included investigating the effects on cognition of cognitive training (CT) programs using video games compared to programs using entertainment games or to low-intensity CT games. Despite the growing number of studies, many of them were focused on cognitive rehabilitation in elderly people with some degree of cognitive impairment, and few involved training among healthy elderly people.Conclusion According to the studies analyzed, the interventions involving CT with video games promoted significant improvements in processing speed and working memory, but no improvements in executive functions.
- Predicting Dementia Due to Alzheimer's Disease and Behavioral Variant Frontotemporal Dementia Using Algorithms with the Addenbrooke's Cognitive Examination-Revised Subscores Combined with Sociodemographic Factors(2023) AMARAL-CARVALHO, Viviane; LIMA-SILVA, Thais Bento; MARIANO, Luciano Inacio; SOUZA, Leonardo Cruz de; GUIMARAES, Henrique Cerqueira; BAHIA, Valeria Santoro; NITRINI, Ricardo; BARBOSA, Maira Tonidandel; YASSUDA, Monica Sanches; CARAMELLI, PauloBackground: Alzheimer's disease (AD) and behavioral variant frontotemporal dementia (bvFTD) are important causes of dementia with challenging differential diagnoses in many cases. Addenbrooke's Cognitive Examination-Revised (ACE-R) is a cognitive battery that may be useful to differentiate the two disorders.Objective: The objectibe of this study is to investigate the value of the ACE-R combined with sociodemographic factors in the differential diagnosis between AD and bvFTD.Methods The ACE-R was administered to 102 patients with mild dementia due to probable AD, 37 with mild bvFTD, and 135 controls. Performances of patients and controls were analyzed by logistic regression and by ROC curves to refine the diagnostic accuracy of the ACE-R in AD and bvFTD.Results: The ACE-R subscores Attention and Orientation, Fluency, and Memory, in combination with schooling differentiated AD from controls with an area under the ROC curve (AUC) of 0.936 (86% sensitivity and 87% specificity). The ACE-R subscores Attention and Orientation, Fluency, and Language, in combination with sex (male), age, and schooling, discriminated bvFTD from controls with an AUC of 0.908 (81% sensitivity and 95% specificity). In the differentiation between AD and bvFTD, the ACE-R subscores Attention and Orientation, Fluency, and Language, together with age, displayed an AUC of 0.865 (78% sensitivity and 85% specificity).Conclusion: The combination of ACE-R scores with sociodemographic data allowed good differentiation between AD and bvFTD in the study sample.
- Subjective impacts of computerized cognitive training for healthy older adults in the context of the COVID-19 pandemic(2023) VIVIANI, Cristiane Benedita Rodrigues da Mota Antunes; ORDONEZ, Tiago Nascimento; PEREIRA, Andreia Rodrigues; JARDIM, Karen de Souza; BORGES, Jonatas da Hora; MOTA, Lais Aparecida Pereira; SANTOS, Gabriela dos; MOREIRA, Ana Paula Bagli; VERGA, Cassia Elisa Rossetto; ISHIBASHI, Graciela Akina; SILVA, Guilherme Alves da; MORAES, Luiz Carlos de; LESSA, Patricia Prata; GUTIERREZ, Beatriz Aparecida Ozello; BRUCKI, Sonia Maria Dozzi; SILVA, Thais Bento Lima daBackground Computerized cognitive training programs may have benefited the self-assessment of memory, quality of life, and mood among older adults during the coronavirus disease 2019 (COVID-19) pandemic. Objective To determine the subjective impacts of computerized cognitive training on mood, frequency of forgetfulness, memory complaints, and quality of life in the elderly using an online platform. Methods In total, 66 elderly participants of USP 60thorn, a program for the elderly offered by Universidade de Sao Paulo, who voluntarily enrolled in the study were selected and randomized with an allocation ratio of 1:1 into 2 groups: the training group (n = 33) and the control group (n = 33). After signing the free and informed consent form, they answered a protocol which included a sociodemographic questionnaire, the Memory Complaints Questionnaire (MAC-Q), the McNair and Kahn's Frequency of Forgetfulness Scale, the Geriatric Depression Scale (GDS-15), the Geriatric Anxiety Inventory (GAI), and the Control, Autonomy, Self-Realization, and Pleasure (CASP-19) questionnaire. The training cognitive game platform aimed to stimulate various cognitive aspects, including memory, attention, language, executive functions (reasoning, logical thinking), and visual and spatial skills. Results The participants of the training group showed a reduction in the MAC-Q, MacNair and Kahn, and GAI scores in the pre- and posttest comparison. Significant differences were identified between the groups regarding the total scores of theMAC-Q in the post-test, which was also evidenced by the logistic regression. Conclusion Participation in a computerized cognitive intervention promoted reductions in memory complaints, frequency of forgetfulness, and anxiety symptoms, in addition to improving self-reported quality of life.
- Social distancing, emotional suffering, and cognitive performance in mature and older adults: a literature review(2023) SANTOS, G. Dos; LIMA-SILVA, T. B.Variables related to social distancing can have negative effects on the emotional well-being and cognition of adults and the elderly. Objective: The aim of this study was to analyze the available studies that address the relationship between situations of social distancing, socioemotional aspects, and cognition in the lives of mature and older adults. Methods: A literature review study was carried out between December 2021 and January 2022, involving the SciELO, PubMed, and ScienceDirect databases, with studies published between February 2018 and December 2021. Results: A total of 754 studies were identified, and after selection, 18 were included. Notably, 16 showed significant effects of social distancing on cognition and socioemotional aspects, that is, the greater the social distancing, the lower the capacity for cognitive performance and the higher the index of symptoms of depression and anxiety, for example. Conclusions: Greater engagement in social activities and a closer contact with friends and family are protective factors against symptoms of depression and anxiety and cognitive decline.
- The presence of depressive symptoms and cognitive performance among older individuals with and without self-reported chronic diseases(2023) SILVA, Thaís Bento Lima da; ORDONEZ, Tiago Nascimento; SILVA, Guilherme Alves da; SOUZA, Maria Antônia Antunes de; SILVA, Sabrina Aparecida da; SANTOS, Gabriela dos; GUTIERREZ, Beatriz Aparecida Ozello; MOREIRA, Ana Paula Bagli; COSTA, Laydiane Alves; MORAES, Luiz Carlos de; LESSA, Patrícia Prata; CARDOSO, Neide Pereira; SAKAGUCHI, Mitsuru; SILVA, Henrique Salmazo da; BRUCKI, Sonia Maria DozziABSTRACT. Dementias secondary to cardiovascular diseases are the second cause of neurogenerative diseases. These conditions can be prevented by controlling risk factors, and it is necessary to observe the relationship between chronic diseases. Objective: to know the influence of chronic non-communicable diseases on cognition and depressive symptoms in the elderly, amid the COVID-19 pandemic. Methods: 578 older adults were evaluated using a sociodemographic questionnaire, the Brazilian Telephone version of the Mini Mental State Examination (Braztel-MMSE), the Geriatric Depression Scale (GDS-15) and an open questionnaire related to NCDs. Results: the association of Non-Communicable Diseases (NCD) with age, depressive symptoms and schooling was confirmed. Conclusion: no association with cognitive decline was evident due to the relationship of high schooling of participants and control of NCDs.