ERIC HOMERO ALBUQUERQUE PASCHOAL
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- Cerebral hemodynamic and metabolic changes in fulminant hepatic failure(2017) PASCHOAL JUNIOR, Fernando Mendes; NOGUEIRA, Ricardo de Carvalho; OLIVEIRA, Marcelo de Lima; PASCHOAL, Eric Homero Albuquerque; TEIXEIRA, Manoel Jacobsen; D'ALBUQUERQUE, Luiz Augusto Carneiro; BOR-SENG-SHU, EdsonIntracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.
- Embolic Signals during Routine Transcranial Doppler Ultrasonography in Aneurysmal Subarachnoid Hemorrhage(2015) PASCHOAL JR., Fernando Mendes; RONCONI, Karla de Almeida Lins; OLIVEIRA, Marcelo de Lima; NOGUEIRA, Ricardo de Carvalho; PASCHOAL, Eric Homero Albuquerque; TEIXEIRA, Manoel Jacobsen; FIGUEIREDO, Eberval Gadelha; BOR-SENG-SHU, EdsonIntroduction. Cerebral emboli may occur in subarachnoid hemorrhage (SAH) and intracranial aneurysm surgery. Although embolic signs (ES) have been reported in SAH, their origin remains unclear. The aim of this study was to report the detection of ES during routine TCD monitoring in patients with aneurysmal SAH. Methods. A total of 105 patients with aneurysmal SAH were submitted to TCD evaluation. Patients were monitored almost daily (5 times per week). In each monitoring session, one experienced operator performed TCD to detect or assess vasospasm and ES in arteries of the Willis polygon. Results. Four patients out of a total of 105 patients with aneurysmal SAH were found to present spontaneous cerebral embolization during routine TCD monitoring. The average age of the 4 patients (mean +/- standard deviation) was 59.5 +/- 8.34 years (range 49-68 ys); female patients predominated representing 75%(3/4) of subjects. Conclusion. Although detection of ES was relatively rare in this study, rates of emboli occurrence may be higher under systematic monitoring. The detection of ES after SAH surgery reinforces the need to study the role of embolus in this condition and may be an indicator for prophylactic antithrombotic treatment.
- Cerebral autoregulation in a fulminant hepatic failure patient who underwent liver transplantation(2019) PASCHOAL- JR., Fernando M.; NOGUEIRA, Ricardo C.; DE-LIMA-OLIVEIRA, Marcelo; PASCHOAL, Eric H.; TEIXEIRA, Manoel J.; D'ALBUQUERQUE, Luiz A.; BOR-SENG-SHU, Edson