MARIA MANUELA FERREIRA ALVES DE ALMEIDA
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas, Faculdade de Medicina
LIM/24 - Laboratório de Oncologia Experimental, Hospital das Clínicas, Faculdade de Medicina
LIM/24 - Laboratório de Oncologia Experimental, Hospital das Clínicas, Faculdade de Medicina
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- Appetite Assessment of Hospitalized Cancer Patients in Brazil - A Validation Study(2019) OZORIO, Gislaine Aparecida; ALMEIDA, Maria Manuela Ferreira Alves de; FARIA, Sheilla de Oliveira; CARDENAS, Thais de Campos; WAITZBERG, Dan LinetzkyOBJECTIVES: Appetite loss, a common symptom in cancer patients, contributes to worsened nutritional status. A validated specific tool to assess appetite is clinically useful for diagnosing and identifying symptoms and signs that could be reversed with nutritional and pharmacological therapies. The aim of this study is to produce a Brazilian Portuguese version of the Hill and Blundell visual analog scale (VAS) for appetite and investigate its validity among hospitalized cancer patients. METHODS: The original English VAS version was translated into Brazilian Portuguese in full accordance with the guidelines in the literature and adapted to the Brazilian context by conducting interviews and meetings with an expert committee until the final version was reached. Afterwards, the version was validated in hospitalized cancer patients in a cross-sectional study at Sao Paulo Cancer Institute (ICESP), where the relationships between breakfast intake (rest-ingestion index) and VAS were compared. The Spearman test was used to verify the correlation between the rest-ingestion index and the VAS ratings. RESULTS: Sixty-four patients with a mean age of 56.1 (+/- 12.3) years answered the Portuguese VAS version, and their breakfast intake was evaluated. The mean rest-ingestion index was 18.8%. The correlations between the rest-ingestion index (food acceptance) and three questions of the Portuguese visual analog scale version were inverse and significant: first question (rho -0.3028 p=0.0046), second question (rho -0.2317 p=0.0319) and third question (rho -0.3049 p=0.0043). CONCLUSION: The ""Appetite Assessment Scale of Brazilian Oncology Patients"" is a valid instrument to assess appetite in hospitalized cancer patients in Brazil.
bookPart Indicadores de Nutrição Clínica(2015) GANDOLFO, Adriana Servilha; SILVA, Ana Cláudia da; VALADARES, Andressa Tamasco; TEIXEIRA, Cláudia de Fátima Gomes; BASSINELLO, Giordanna Luiggia Budroni; LOPES, Helen Cristina Bittencourt; COSTA, Helenice Moreira da; SILVA, Jéssica Helena da; VIEIRA, Lis Proença; ALMEIDA, Maria Manuela Ferreira Alves de; SATO, Olga Miyuki; ZAMBERLAM, Patrícia; TRECCO, Sonia Maria Lopes de Souza Sanches; CARDENAS, Thais de Campos; SCHIESARI, Thaís Manoel Bispo; OLIVEIRA, Vanessa da Cunha; ROSA, Vitor Modesto- Exploring the use of the GLIM criteria to diagnose malnutrition in cancer inpatients(2023) OZORIO, Gislaine Aparecida; RIBEIRO, Lia Mara Kauchi; SANTOS, Barbara Chaves; BRUZACA, Wannia Ferreira de Sousa; ROCHA, Gabriela Del Gallo Vieira da; MARCHI, Luani Maria da Fonseca; SANTOS, Fernando Magri; ALMEIDA, Maria Manuela Ferreira Alves de; KULCSAR, Marco Aurelio Vamondes; RIBEIRO, Ulysses; CORREIA, Maria Isabel Toulson Davisson; WAITZBERG, Dan LinetzkyObjectives: The Global Leadership Initiative on Malnutrition (GLIM) criteria establish a diagnosis of malnutrition based on the presence of at least one phenotypic and one etiologic criterion. This study aimed to assess the concurrent and predictive validity of the GLIM criteria in hospitalized cancer patients.Methods: This is an observational retrospective study, including 885 cancer patients, ages >18 y, admitted to a medical oncology inpatient unit between 2019 and 2020. All patients at risk for malnutrition according to the Nutritional Risk Screening 2002 score were assessed by the subjective global assessment (SGA) and 14 different combinations of the GLIM criteria. The SGA was considered the gold standard for assessing the con-current validity of the GLIM combinations. For a subsample of patients with data available on inflammatory markers (n = 198), the serum albumin and C-reactive protein were included in the combinations as etiologic criteria. The predictive validity of the different combinations was tested using the occurrence of surgical complications as the clinical outcome. The sensitivity and specificity values were calculated to assess the con-current validity, univariate and multivariate logistic regression models were used to test predictive validity. Adequate concurrent and predictive validity were determined as sensitivity and specificity values >80% and odds ratio values >2.0, respectively.Results: The median age of the patients was 61.0 y (interquartile range = 51.0-70.0). Head and neck cancer was the prevailing diagnosis and 375 patients were at nutritional risk. According to the SGA, 173 (26.1%) patients were malnourished (SGA categories B or C) and the prevalence of malnutrition ranged from 3.9% to 30.0%, according to the GLIM combinations. None of the tested combinations reached adequate concurrent validity; however, the presence of malnutrition according to four combinations independently predicted surgical complications.Conclusions: The predictive validity of the GLIM was satisfactory in surgical cancer patients.
bookPart Protocolo de tratamento da fadiga oncológica(2014) VELAR, Camila Molina; BRITO, Christina May Moran de; REIS, Fabiana; ANDRADE, Lydia Caldeira Tavares de Oliveira; ALMEIDA, Maria Manuela Ferreira Alves de; SANTOS, Patricia Cunha