BRUNO GUALANO
Projetos de Pesquisa
Unidades Organizacionais
Departamento de Clínica Médica, Faculdade de Medicina - Docente
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/17 - Laboratório de Investigação em Reumatologia, Hospital das Clínicas, Faculdade de Medicina - Líder
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
conferenceObject Creatine In Osteoarthritis, A Randomized, Double-blinded, Placebo-controlled Trial(2012) ROSCHEL, Hamilton; NEVES- JR., Manoel; FULLER, Ricardo; BENATTI, Fabiana; PINTO, Ana Lucia Sa; LIMA, Fernanda R.; PEREIRA, Rosa M.; LANCHA- JR., Antonio H.; BONFA, Eloisa; GUALANO, Bruno- Creatine supplementation does not augment muscle carnosine content in type 2 diabetic patients (vol 36, pg 764, 2011)(2012) GUALANO, Bruno; LUGARESI, Rebeca; PAINELLI, Vitor de Salles; QUEIROZ, Andreia Cristina Carrenho; ARTIOLI, Guilherme; ROSCHEL, Hamilton; OTADUY, Maria Concepcion; LEITE, Claudia da Costa; LANCHA JR., Antonio Herbert
- Similar Health Benefits of Endurance and High-Intensity Interval Training in Obese Children(2012) ARAUJO, Ana Carolina Corte de; ROSCHEL, Hamilton; PICANCO, Andreia Rossi; PRADO, Danilo Marcelo Leite do; VILLARES, Sandra Mara Ferreira; PINTO, Ana Lucia de Sa; GUALANO, BrunoPurpose: To compare two modalities of exercise training (i.e., Endurance Training [ET] and High-Intensity Interval Training [HIT]) on health-related parameters in obese children aged between 8 and 12 years. Methods: Thirty obese children were randomly allocated into either the ET or HIT group. The ET group performed a 30 to 60-minute continuous exercise at 80% of the peak heart rate (HR). The HIT group training performed 3 to 6 sets of 60-s sprint at 100% of the peak velocity interspersed by a 3-min active recovery period at 50% of the exercise velocity. HIT sessions last similar to 70% less than ET sessions. At baseline and after 12 weeks of intervention, aerobic fitness, body composition and metabolic parameters were assessed. Results: Both the absolute (ET: 26.0%; HIT: 19.0%) and the relative VO2 peak (ET: 13.1%; HIT: 14.6%) were significantly increased in both groups after the intervention. Additionally, the total time of exercise (ET: 19.5%; HIT: 16.4%) and the peak velocity during the maximal graded cardiorespiratory test (ET: 16.9%; HIT: 13.4%) were significantly improved across interventions. Insulinemia (ET: 29.4%; HIT: 30.5%) and HOMA-index (ET: 42.8%; HIT: 37.0%) were significantly lower for both groups at POST when compared to PRE. Body mass was significantly reduced in the HIT (2.6%), but not in the ET group (1.2%). A significant reduction in BMI was observed for both groups after the intervention (ET: 3.0%; HIT: 5.0%). The responsiveness analysis revealed a very similar pattern of the most responsive variables among groups. Conclusion: HIT and ET were equally effective in improving important health related parameters in obese youth.
- Incidence of adverse events associated with percutaneous muscular biopsy among healthy and diseased subjects(2012) NEVES JR., M.; BARRETO, G.; BOOBIS, L.; HARRIS, R.; ROSCHEL, H.; TRICOLI, V.; UGRINOWITSCH, C.; NEGRAO, C.; GUALANO, B.The development of the percutaneous muscle biopsy technique is recognized as one of the most important scientific contributions in advancing our understanding of skeletal muscle physiology. However, a concern that this procedure may be associated with adverse events still exists. We reported the incidence of adverse outcomes associated with percutaneous muscle biopsy in healthy and diseased subjects. Medical records of 274 volunteers (496 muscle biopsies) were reviewed. This included 168 healthy subjects (330 muscle biopsies) as well as 106 chronically ill patients (166 muscle biopsies). This latter group encompassed patients with type II diabetes (n=28), osteoarthritis (n=39), inclusion body myositis (n=4), polymyositis (n=4), and chronic heart failure (n=31). The most common occurrences were pain (1.27%), erythema (1.27%), and ecchymosis (1.27%). Panic episode, bleeding, and edema were also reported (0.21%, 0.42%, and 0.84%, respectively), while infection, hematoma, inflammation, denervation, numbness, atrophy, and abnormal scarring were not verified. The percent of incidents did not differ between healthy and ill individuals. In conclusion, the incidence of complications associated with percutaneous muscle biopsy is scarce and of minor clinical relevance. Additionally, the rate of adverse events is comparable between healthy and chronically ill subjects.
conferenceObject Effects Of Sprint Interval And Traditional Endurance Training On Heart Rate Recovery In Obese Children(2012) ARAUJO, Ana Carolina C.; PINTO, Ana Lucia S.; ROSCHEL, Hamilton; PRADO, Danilo L.; PERONDI, Maria Beatriz; VILLARES, Sandra M.; GUALANO, Bruno- Exercise as a therapeutic tool to counteract inflammation and clinical symptoms in autoimmune rheumatic diseases(2012) PERANDINI, Luiz Augusto; SA-PINTO, Ana Lucia de; ROSCHEL, Hamilton; BENATTI, Fabiana Braga; LIMA, Fernanda Rodrigues; BONFA, Eloisa; GUALANO, BrunoChronic inflammation is a common feature shared by several autoimmune rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, idiopathic inflammatory myopathies, systemic sclerosis, and ankylosing spondylitis. Therefore, blocking or reducing inflammation is one of the major treatment strategies in these diseases. In this context, exercise training has emerged as a potential therapeutic tool in counteracting systemic inflammation, thereby leading to better clinical outcomes. The aims of this review are i) to provide a summary of the clinical effects of exercise training in selected autoimmune rheumatic diseases; and ii) to discuss the potential anti-inflammatory role of exercise training in autoimmune rheumatic diseases, stressing the gaps in literature and the clinical and scientific perspectives in the field.
conferenceObject Exercise Training Attenuates Total And Visceral Fat Compensatory Growth In Women Submitted To Abdominal Liposuction(2012) BENATTI, Fabiana B.; MONTAG, Eduardo; SOLIS, Marina Y.; SAITO, Fabio L.; BAPTISTA, Luciana P.; TERUYA, Alexandre; GUALANO, Bruno; PAINELLI, Vitor S.; LIMA, Fernanda R.; SEIXAS, Daniela F. C.; COSTA, Luiz Augusto R.; LANCHA JR., Antonio H.