MARIA FERNANDA ABALEM DE SA CARRICONDO
Projetos de Pesquisa
Unidades Organizacionais
Instituto Central, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
LIM/33 - Laboratório de Oftalmologia, Hospital das Clínicas, Faculdade de Medicina
6 resultados
Resultados de Busca
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conferenceObject Enhanced Depth Image Optical Coherence Tomography (EDI-OCT) choroidal evaluation in patients with diabetes and correlation with retinal and kidney disease(2016) ABALEM, Maria Fernanda; PRETI, Rony Carlos; GARCIA, Rafael; SANTOS, Helen Nazareth Veloso; CARRICONDO, Pedro C.; PIMENTEL, Sergio Luis Gianotti; TAKAHASHI, Walter Y.; MONTEIRO, Mario L. R.- Prevalence of Focal Inner, Middle, and Combined Retinal Thinning in Diabetic Patients and Its Relationship With Systemic and Ocular Parameters(2021) PRETI, Rony Carlos; IOVINO, Claudio; ABALEM, Maria Fernanda; GARCIA, Rafael; SANTOS, Helen Nazareth Veloso dos; SAKUNO, Gustavo; AU, Adrian; CUNHA, Leonardo Provetti; ZACHARIAS, Leandro Cabral; MONTEIRO, Mario Luiz Ribeiro; SADDA, Srinivas Reddy; SARRAF, DavidPurpose: To determine the prevalence of focal inner, middle, and combined inner/middle retinal thinning (FIRT, FMRT, and FCRT, respectively) in different stages of diabetic retinopathy (DR) without diabetic macular edema and to assess the relationship between such findings with ocular and systemic parameters. Methods: This was a cross-sectional, comparative study comprising healthy participants and diabetic patients with different stages of DR. Forty-nine horizontal macular B-scans from the selected eye were obtained using spectral-domain optical coherence tomography (SD-OCT) and analyzed for the presence of FIRT, FMRT, or FCRT and any relationship with systemic and ocular parameters. Focal retinal thinning (FRT) was subjectively defined as any evidence of inner and/or middle retinal thinning. Results: A total of 190 participants (52 healthy participants and 138 diabetic patients) were included. A higher prevalence of FRT was observed in eyes with advanced DR versus healthy eyes and versus diabetic eyes with no DR or mild DR. FIRT and FCRT were significantly greater in eyes with proliferative DR treated with pan-retinal photocoagulation, and FMRT was significantly more common in eyes with severe nonproliferative DR. FRT was significantly more common in patients with coronary artery disease and was positively correlated with diabetes duration, serum creatinine, and glycosylated hemoglobin and negatively correlated with age, estimated glomerular filtration rate, and visual acuity. Conclusions: FRT occurs in all stages of DR and is increasingly prevalent with increasing severity of DR. Translational Relevance: OCT identification of FRT may provide a surrogate biomarker of retinal and systemic disease in diabetic patients.
conferenceObject Correlation of Enhanced Depht Imaging Optical Coherence Tomography (EDI-OCT) choroidal findings and visual acuity in sickle cell disease(2016) CARRICONDO, Pedro C.; ABALEM, Maria Fernanda; BONANOMI, Maria Teresa B. C.; PRETI, Rony; PIMENTEL, Sergio Luis Gianotti; MONTEIRO, Mario L. R.; TAKAHASHI, Walter Y.conferenceObject Foveal choroidal thickness using spectral-domain optical coherence tomography in diabetic patients during the water-drinking test(2016) PRETI, Rony; ABALEM, Maria Fernanda; GARCIA, Rafael; SANTOS, Helen Nazareth Veloso; CARRICONDO, Pedro C.; ZACHARIAS, Leandro C.; PIMENTEL, Sergio Luis Gianotti; SUSANNA, Remo; TAKAHASHI, Walter Y.; MONTEIRO, Mario L. R.conferenceObject Retinal blood vessels diameters in unilateral ischemic central retinal vein occlusion using infrared imaging.(2016) GARCIA, Rafael; ABALEM, Maria Fernanda; PRETI, Rony; SANTOS, Helen Nazareth Veloso; CARRICONDO, Pedro Carlos; ZACHARIAS, Leandro C.; PIMENTEL, Sergio Luis Gianotti; TAKAHASHI, Walter Y.; MONTEIRO, Mario L. R.- Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing's Syndrome(2016) ABALEM, Maria Fernanda; MACHADO, Marcio Carlos; SANTOS, Helen Nazareth Veloso Dos; GARCIA, Rafael; HELAL JR., John; CARRICONDO, Pedro Carlos; PIMENTEL, Sergio Luis Gianotti; MONTEIRO, Mario Luiz Ribeiro; QIAN, Cynthia X.; BRONSTEIN, Marcello Delano; FRAGOSO, Maria Candida Villares BarissonContext: Cortisol has been suggested as a risk factor for choroidal thickening, which may lead to retinal changes. Objective: To compare choroidal thickness measurements using optical coherence tomography (OCT) in patients with endogenous active Cushings syndrome (CS) and to evaluate the occurrence of retinal abnormalities in the same group of patients. Design: Cross-sectional study. Setting: Outpatient clinic. Patients: Eleven female patients with CS in hypercortisolism state as determined by the presence of at least two abnormal measurements from urinary cortisol 24 h, no suppression of cortisol with low dose dexamethasone suppression test, and nocturnal salivary cortisol levels and 12 healthy controls. Methods: Choroidal and retinal morphology was assessed using OCT. Main outcome measures: Choroidal thickness measurements and the presence of retinal changes. Results: The mean subfoveal choroidal thickness was 372.96 +/- 73.14 m in the patients with CS and 255.63 +/- 50.70 mu m in the control group (p < 0.001). One patient (9.09%) presented with central serous chorioretinopathy and one patient (9.09%) with pachychoroid pigment epitheliopathy. Conclusion: Choroidal thickness is increased in the eyes of patients with active CS compared to healthy and matched control. Also, 18.18% of patients presented with macular changes, possibly secondary to choroidal thickening. While further studies are necessary to confirm our findings, excess corticosteroid levels seem to have a significant effect on the choroid and might be associated with secondary retinal diseases.