MARIO AUGUSTO TARICCO
Projetos de Pesquisa
Unidades Organizacionais
LIM/45 - Laboratório de Fisiopatologia Neurocirúrgica, Hospital das Clínicas, Faculdade de Medicina
7 resultados
Resultados de Busca
Agora exibindo 1 - 7 de 7
- Professor Luiz Alcides Manreza IN MEMORIAM(2012) BACHESCHI, Luiz Alberto; TARICCO, Mario Augusto; REED, Umbertina Conti
- The history of neurosurgery at the University of Sao Paulo(2014) TEIXEIRA, Manoel Jacobsen; FIGUEIREDO, Eberval Gadelha; TARICCO, Mario Augusto; PLESE, Jose Pindaro P.; FLORES, Camila; TEIXEIRA, Saulo A.; LUZIO, JoseThe history of neurosurgery at University of São Paulo comes from 1918, since its origins under the Department of Neurology from Chair of Psychiatric Clinic and Nervous Diseases. Professor Enjolras Vampré was the great inspiration for such medical specialty in the State of Sao Paulo. In 1929, the first neurosurgical procedures were performed in the recently (at time) organized Section of Neurosurgery. The official inauguration of the Division of Functional Neurosurgery occurred at June 1977, with the presence of worldwide well-known neuroscientists. The division suffered a deep streamlining under the leadership of Professor Raul Marino Jr., between the decades of 1990 and 2000. At this time, it was structured with the sections of neurological surgery, functional neurosurgery and neurosurgical emergency. Since 2008, Professor Manoel Jacobsen Teixeira is the Chairman of the Division and has provided the Division with the best available technological resources, performing more than 3,000 surgeries a year and training professionals who will, certainly, be some of the future leaders of brazilian neurosurgery.
- Reliability and safety of a new upper cervical spine injury treatment algorithm(2017) JOAQUIM, Andrei Fernandes; BROCK, Roger Schmidt; GUIRADO, Vinicius Monteiro de Paula; SANDON, Luis Henrique; SILVA, Otavio Turolo da; TARICCO, Mario Augusto; TEIXEIRA, Manoel Jacobsen; FIGUEIREDO, Eberval GadelhaIn the present study, we evaluated the reliability and safety of a new upper cervical spine injury treatment algorithm to help in the selection of the best treatment modality for these injuries. Methods: Thirty cases, previously treated according to the new algorithm, were presented to four spine surgeons who were questioned about their personal suggestion for treatment, and the treatment suggested according to the application of the algorithm. After four weeks, the same questions were asked again to evaluate reliability (intra-and inter-observer) using the Kappa index. Results: The reliability of the treatment suggested by applying the algorithm was superior to the reliability of the surgeons' personal suggestion for treatment. When applying the upper cervical spine injury treatment algorithm, an agreement with the treatment actually performed was obtained in more than 89% of the cases. Conclusion: The system is safe and reliable for treating traumatic upper cervical spine injuries. The algorithm can be used to help surgeons in the decision between conservative versus surgical treatment of these injuries.
article 3 Citação(ões) na Scopus Intramedullary granuloma suggestive of tuberculoma(2011) GUIRADO, Vinicius M.; WELLING, Leonardo C.; MELUZZI, Alexandre; SANTOS, Marcelo E. Sette dos; FIGUEIREDO, Eberval Gadelha; TARICCO, Mario Augusto; TEIXEIRA, Manoel Jacobsen- Immunohistochemical expression of cyclin D1 is higher in supratentorial ependymomas and predicts relapses in gross total resection cases(2015) ANDRADE, Fernanda Goncalves de; MARIE, Suely Kazue Nagahashi; UNO, Miyuki; MATUSHITA, Hamilton; TARICCO, Mario Augusto; TEIXEIRA, Manoel Jacobsen; ROSEMBERG, Sergio; OBA-SHINJO, Sueli MiekoEpendymomas are tumors of the CNS. Although cyclin D1 overexpression has been related to several cancers, its prognostic value in ependymomas has not yet been fully established. We evaluated cyclin D1 expression by an immunohistochemistry analysis of 149 samples of ependymomas, including some relapses, corresponding to 121 patients. Eighty-one patients were adults, 60 were intracranial cases and 92 tumors were grade II. Gross total resection (GTR) was achieved in 62% of cases, and relapse was confirmed in 41.4% of cases. Cyclin D1 protein expression was analyzed by immunohistochemistry and scored with a labeling index (LI) calculated as the percentage of positively stained cells by intensity. We also analyzed expression of CCND1 and NOTCH1 in 33 samples of ependymoma by quantitative real-time PCR. A correlation between cyclin D1 LI score and anaplastic cases (P<0.001), supratentorial location (P<0.001) and age (P=0.001) were observed. A stratified analysis demonstrated that cyclin D1 protein expression was strong in tumors with a supratentorial location, independent of the histological grade or age. Relapse was more frequent in cases with a higher cyclin D1 LI score (P=0.046), and correlation with progression-free survival was observed in cases with GTR (P=0.002). Only spinal canal tumor location and GTR were suggestive markers of PFS in multivarite analyses. Higher expression levels were observed in anaplastic cases for CCND1 (P=0.002), in supratentorial cases for CCND1 (P=0.008) and NOTCH1 (P=0.011). There were correlations between the cyclin D1 mRNA and protein expression levels (P<0.0001) and between CCND1 and NOTCH1 expression levels (P=0.003). Higher cyclin D1 LI was predominant in supratentorial location and predict relapse in GTR cases. Cyclin D1 could be used as an immunohistochemical marker to guide follow-up and treatment in these cases.
- Spinal melanotic schwannomas(2012) WELLING, Leonardo C.; GUIRADO, Vinicius M. P.; TESSARI, Marcelo; FELIX, Alexandre R.; ZANELLATO, Cristina; FIGUEIREDO, Eberval G.; TARICCO, Mario Augusto; TEIXEIRA, Manoel Jacobsen
- Survival score scales of patients operated with spinal metastases: retrospective application in a Brazilian population(2016) RIBAS, Eduardo Carvalhal; MATHIAS JUNIOR, Luis Roberto; GUIRADO, Vinicius Monteiro; BROCK, Roger Schmidt; TARICCO, Mario Augusto; DANIEL, Mauro Miguel; LOURENCO, Rafael Burgomeister; TEIXEIRA, Manoel JacobsenSpinal cord epidural metastasis (SEM) is a common complication of systemic cancer. Predicting these patient's survival is a key factor to select the proper treatment modality, but the three most used score scales to predict their survival (Tokuhashi revised score, Tomita score and Bauer modified score) were designed in single institutions and their reliability to predict correctly the patient's survival were first tested only in those specific populations. This prognostication issue is addressed in this article, evaluating retrospectively the survival of 17 patients with SEM from a Brazilian general hospital with these score scales. Our results show that the actual survival of those patients were worse than the predicted of all three score scales, suggesting that differences between the different populations might have affected their reliability and alert that their usage as a major factor to select the most appropriate treatment have to be done with caution.