WILLIAM OMAR CONTRERAS LOPEZ
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- Aesthetically optimal deep brain stimulation technique in patients with alopecia(2015) FONOFF, Erich Talamoni; TEIXEIRA, Manoel Jacobsen; NASCIMENTO, Clarissa Nobrega Gambarra; LOPEZ, William Omar
article 11 Citação(ões) na Scopus Pain Relief in CRPS-II after Spinal Cord and Motor Cortex Simultaneous Dual Stimulation(2016) LOPEZ, William O. C.; BARBOSA, Danilo C.; TEIXEIRA, Manoel J.; PAIZ, Martin; MOURA, Leonardo; MONACO, Bernardo A.; FONOFF, Erich T.We describe a case of a 30-year-old woman who suffered a traumatic injury of the right brachial plexus, developing severe complex regional pain syndrome type II (CRPS-II). After clinical treatment failure, spinal cord stimulation (SCS) was indicated with initial positive pain control. However, after 2 years her pain progressively returned to almost baseline intensity before SCS. Additional motor cortex electrode implant was then proposed as a rescue therapy and connected to the same pulse generator. This method allowed simultaneous stimulation of the motor cortex and SCS in cycling mode with independent stimulation parameters in each site. At 2 years follow-up, the patient reported sustained improvement in pain with dual stimulation, reduction of painful crises, and improvement in quality of life. The encouraging results in this case suggests that this can be an option as add-on therapy over SCS as a possible rescue therapy in the management of CRPS-II. However, comparative studies must be performed in order to determine the effectiveness of this therapy.- Optical coherence tomography imaging of the basal ganglia: feasibility and brief review(2015) LOPEZ, W. O. Contreras; ANGELOS, J. S.; MARTINEZ, R. C. R.; TAKIMURA, C. K.; TEIXEIRA, M. J.; LEMOS NETO, P. A.; FONOFF, E. T.Optical coherence tomography (OCT) is a promising medical imaging technique that uses light to capture real-time cross-sectional images from biological tissues in micrometer resolution. Commercially available optical coherence tomography systems are employed in diverse applications, including art conservation and diagnostic medicine, notably in cardiology and ophthalmology. Application of this technology in the brain may enable distinction between white matter and gray matter, and obtainment of detailed images from within the encephalon. We present, herein, the in vivo implementation of OCT imaging in the rat brain striatum. For this, two male 60-day-old rats (Rattus norvegicus, Albinus variation, Wistar) were stereotactically implanted with guide cannulas into the striatum to guide a 2.7-French diameter high-definition OCT imaging catheter (Dragonfly (TM), St. Jude Medical, USA). Obtained images were compared with corresponding histologically stained sections to collect imaging samples. A brief analysis of OCT technology and its current applications is also reported, as well as intracerebral OCT feasibility on brain mapping during neurosurgical procedures.