MARIA LUIZA BAGGIO GARCIA PINTO
Índice h a partir de 2011
12
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LIM/24 - Laboratório de Oncologia Experimental, Hospital das Clínicas, Faculdade de Medicina
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article 13 Citação(ões) na Scopus Concordance of Beta-papillomavirus across anogenital and oral anatomic sites of men: The HIM Study(2017) NUNES, Emily M.; LOPEZ, Rossana V. M.; SUDENGA, Staci L.; GHEIT, Tarik; TOMMASINO, Massimo; BAGGIO, Maria L.; FERREIRA, Silvaneide; GALAN, Lenice; SILVA, Roberto C.; LAZCANO-PONCE, Eduardo; GIULIANO, Anna R.; VILLA, Luisa L.; SICHERO, LauraWe evaluated the concordance between beta-HPVs detected in external genital skin, anal canal, and oral cavity specimens collected simultaneously from 717 men that were participating in the multinational HIM Study. Viral genotyping was performed using the Luminex technology. Species- and type-specific concordance was measured using kappa statistics for agreement. Overall, concordance of P-HPVs across sites was low and mainly observed among paired genital/anal canal samples. When grouped by species, solely beta-4 HPVs showed moderate concordance in genital/anal pairs (k = 0.457), which could be attributed to the substantial concordance of HPV-92 in men from Brazil and Mexico (k > 0.610). beta-HPV type concordance was higher in Mexico, where HPV-19 was consistently concordant in all anatomic site combinations. Our analysis indicates that type-specific concordance across sites is limited to few viral types; however, these infections seem to occur more often than would be expected by chance, suggesting that although rare, there is agreement among sites.- Diversity of beta-papillomavirus at anogenital and oral anatomic sites of men: The HIM Study(2016) NUNES, Emily Montosa; SUDENGA, Staci L.; GHEIT, Tarik; TOMMASINO, Massimo; BAGGIO, Maria Luiza; FERREIRA, Silvaneide; GALAN, Lenice; SILVA, Roberto C.; CAMPBELL, Christine M. Pierce; LAZCANO-PONCE, Eduardo; GIULIANO, Anna R.; VILLA, Luisa L.; SICHERO, LauraOur goal was to describe prevalence of P-HPVs at three anatomic sites among 717 men from Brazil, Mexico and US enrolled in the HPV Infection in Men (HIM) Study. beta-HPVs were genotyped using Luminex technology. Overall, 77.7%, 543% and 293% men were positive for any (beta-HPV at the genitals, anal canal, and oral cavity, respectively. Men from US and Brazil were significantly less likely to have beta-HPV at the anal canal than men from Mexico. Older men were more likely to have (beta-HPV at the anal canal compared to younger men. Prevalence of beta-HPV at the oral cavity was significantly associated with country of origin and age. Current smokers were significantly less likely to have beta-HPV in the oral cavity than men who never smoked. Lack of associations between beta-HPV and sexual behaviors may suggest other routes of contact such as autoinoculation which need to be explored further.