CIDIA VASCONCELLOS
Projetos de Pesquisa
Unidades Organizacionais
LIM/53 - Laboratório de Micologia, Hospital das Clínicas, Faculdade de Medicina
4 resultados
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article 8 Citação(ões) na Scopus Dermatitis herpetiformis Relevance of the physical examination to diagnosis suspicion(2012) CRIADO, Paulo Ricardo; CRIADO, Roberta Fachini Jardim; AOKI, Valeria; BELDA JR., Walter; HALPERN, Ilana; LANDMAN, Gilles; VASCONCELLOS, Cidiaarticle 34 Citação(ões) na Scopus Bedbugs (Cimicidae infestation): the worldwide renaissance of an old partner of human kind(2011) CRIADO, Paulo Ricardo; BELDA JUNIOR, Walter; CRIADO, Roberta Fachini Jardim; SILVA, Roberta Vasconcelos e; VASCONCELLOS, CidiaBedbugs have been known as a human parasite for thousands of years, but scientific studies about this insect are recent and limited. Cimex lectularius, the common bedbug, was a well-known parasite in human dwellings until the end of the Second World War. Nowadays, bedbugs are considered uncommon in the industrialized world. Anecdotal reports suggest that bedbugs are getting more common in the United States, Canada, and United Kingdom. In Brazil, there are few reports about bedbug infestations in the literature. The aim of this article was to alert physicians, especially in Brazil, about this ectoparasitosis, including aspects of the bedbug biology, their parasitism in human host, treatment and prophylaxis.bookPart Reações Cutâneas Adversas às Drogas(2015) CRIADO, Roberta Fachini Jardim; CRIADO, Paulo Ricardo; VASCONCELLOS, Cidia- Immunoelectron microscopy study of superficial skin nerves in drug-induced acute urticaria(2012) CRIADO, Paulo Ricardo; CRIADO, Roberta Fachini Jardim; TAKAKURA, Cleusa F. H.; PAGLIARI, Carla; SOTTO, Mirian Nacagami; VASCONCELLOS, CidiaBACKGROUND: Few studies have evaluated the ultrastructure of the superficial skin nerves in urticaria. OBJECTIVE: The objective of this study was to describe findings in superficial skin nerves in cases of drug-induced acute urticaria. METHODS: Seven patients with drug-induced acute urticaria were included in the study. Skin biopsies were obtained from the urticarial lesion and from the apparently normal skin. The 14 fragments collected were processed for immunogold electron microscopy using single stains for antitryptase and anti-FXIIIa antibodies, as well as double immunogold labeling for both. RESULTS: Some sections showed mast cells in the process of degranulation. Following double immunogold staining, 10 nm (FXIIIa) and 15 nm (Tryptase) gold particles were found together throughout the granules in mast cells, indicating that tryptase and FXIIIa are located inside each one of the granules of these cells. Interestingly, we found strong evidence of the presence of tryptase and factor XIIIa in the superficial skin nerves of these patients, both in cases of urticarial lesions (wheals) and in the apparently normal skin. CONCLUSIONS: Tryptase and FXIIIa are present in the superficial nerves of the skin in drug-induced acute urticaria. This is the first report of tryptase and FXIIIa expression in the superficial skin nerves of patients with urticaria. Tryptase may be participating in neural activation in these patients, while FXIIIa may be present in the nerves to guarantee the functional integrity of structures.