ANDRE LUIZ PEREIRA DE ALBUQUERQUE
Projetos de Pesquisa
Unidades Organizacionais
Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina - Médico
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
LIM/09 - Laboratório de Pneumologia, Hospital das Clínicas, Faculdade de Medicina
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Resultados de Busca
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conferenceObject Diaphragmatic dysfunction in interstitial lung disease: An ultrasonography study(2014) SANTANA, Pauliane Vieira; PRINA, Elena; PLETSCH, Renata; FERREIRA, Jeferson; PEREIRA, Mayra Caleff; US, Andre Apanav; TREVISAN, Patricia; ALBUQUERQUE, Andre P.; CARVALHO, Carlos Roberto R.; CARUSO, PedroconferenceObject Comparison of thoracoabdominal asynchrony estimated via optolectronic and inductive respiratory plethymographies(2014) PEREIRA, Mayra Caleffi; PORRAS, Desiderio Cano; CLAUDINO, Renata Cleia; CARDENAS, Leticia; PLETSCH, Renata; SANTANA, Pauliane; IAMONTI, Vinicius; MALONIR, Renan; CARVALHO, Carlos R. R.; CARVALHO, Celso; ALBUQUERUQE, Andre L. P.- Lung Resection Improves the Quality of Life of Patients With Symptomatic Bronchiectasis(2014) VALLILO, Camilla Carlini; TERRA, Ricardo Mingarini; ALBUQUERQUE, Andre Luis Pereira de; SUESADA, Milena Mako; MARIANI, Alessandro Wasum; SALGE, Joao Marcos; COSTA, Priscila Berenice da; PEGO-FERNANDES, Paulo ManuelBackground. Bronchiectasis is a significant cause of morbidity. Surgical resection is a treatment option, but its main outcomes regarding quality of life (QOL) and physiologic consequences have not been addressed previously, to our knowledge. We aimed to evaluate the effect of surgical procedures on QOL, exercise capacity, and lung function in patients with bronchiectasis in whom medical treatment was unsuccessful. Methods. Patients with noncystic fibrosis in whom medical treatment was unsuccessful and who were candidates for lung resection were enrolled in a prospective study. The main measurements before lung resection and 9 months afterward were QOL according to the Short Form 36 Health Survey and World Health Organization Quality of Life Questionnaires, lung function test results, and the results of maximal cardiopulmonary exercise testing on a cycle ergometer. Results. Of 61 patients who were evaluated, 53 (50.9% male, age 41.3 +/- 12.9 years) underwent surgical resection (83% lobectomies), and 44 completed the 9-month followup. At baseline, they had low QOL scores, mild obstruction, and diminished exercise capacity. After resection, 2 patients died and adverse events occurred in 24.5%. QOL scores improved remarkably at the 9-month measurements, achieving values considered normal for the general population in most dimensions. Functionally, resection caused mild reduction of lung volume; nevertheless, exercise capacity was not decreased. In fact, 52% of the patients improved their exercise performance. Multiple linear regression analysis showed that low QOL before resection was an important predictor of QOL improvement after resection (p = 0.0001). Conclusions. Lung resection promotes a significant improvement in the QOL of patients with noncystic fibrosis bronchiectasis without compromising their exercise capacity. (C) 2014 by The Society of Thoracic Surgeons
- Multiple Benefits of Rehabilitation in a Patient with Heart and Renal Failure(2014) HOSSRI, Carlos Alberto Cordeiro; QUEIROGA JUNIOR, Fernando Jose Pinho; CARVALHO, Vitor Oliveira; CARVALHO, Carlos Roberto Ribeiro; ALBUQUERQUE, Andre Luis Pereira
conferenceObject Comparison of thoracoabdominal asynchrony estimated via optolectronic and inductive respiratory plethymographies(2014) PEREIRA, Mayra Caleffi; PORRAS, Desiderio Cano; CLAUDINO, Renata Cleia; CARDENAS, Leticia; PLETSCH, Renata; SANTANA, Pauliane; LAMONTI, Vinicius; MALONIR, Renan; CARVALHO, Carlos R. R.; CARVALHO, Celso; ALBUQUERUQE, Andre L. P.conferenceObject Stability and agreement of micro-transducer esophageal catheter and air-filled balloon esophageal catheter: in vitro and in vivo study(2014) MALONI, Renan; ALBUQUERUUE, Andre; CARVALHO, Carlos; SALGE, Joao; CARDENAS, Leticia; FERREIRA, Jeferson; LAMONTI, Vinicius; ORLANDIN, Luiz; CARUSO, Pedro- Skeletal Muscle Abnormalities in Pulmonary Arterial Hypertension(2014) BREDA, Ana Paula; ALBUQUERQUE, Andre Luis Pereira de; JARDIM, Carlos; MORINAGA, Luciana Kato; SUESADA, Milena Mako; FERNANDES, Caio Julio Cesar; DIAS, Bruno; LOURENCO, Rafael Burgomeister; SALGE, Joao Marcos; SOUZA, RogerioBackground: Pulmonary arterial hypertension is a progressive disease that is characterized by dyspnea and exercise intolerance. Impairment in skeletal muscle has recently been described in PAH, although the degree to which this impairment is solely determined by the hemodynamic profile remains uncertain. The aim of this study was to verify the association of structural and functional skeletal muscle characteristics with maximum exercise in PAH. Methods: The exercise capacity, body composition, CT area of limb muscle, quality of life, quadriceps biopsy and hemodynamics of 16 PAH patients were compared with those of 10 controls. Results: PAH patients had a significantly poorer quality of life, reduced percentage of lean body mass, reduced respiratory muscle strength, reduced resistance and strength of quadriceps and increased functional limitation at 6MWT and CPET. VO2 max was correlated with muscular variables and cardiac output. Bivariate linear regression models showed that the association between muscular structural and functional variables remained significant even after correcting for cardiac output. Conclusion: Our study showed the coexistence of ventilatory and quadriceps weakness in face of exercise intolerance in the same group of PAH patients. More interestingly, it is the first time that the independent association between muscular pattern and maximum exercise capacity is evidenced in PAH, independently of cardiac index highlighting the importance of considering rehabilitation in the treatment strategy for PAH.