(2022) AMATO, Valdir Sabbaga; SOUZA, Regina Maia de; FRANCO, Lucas Augusto Moyses; MARTINS, Roberta Cristina Ruedas; SILVA, Camila Alves Maia da; EMORI, Christini Takemi; CELESTE, Beatriz Julieta; CASTANHEIRA, Gabriel Victor; TUON, Felipe Francisco
The immunosuppressive effect of methotrexate has rarely been associated with reactivation of cutaneous leishmaniasis. Here we present a case of a cutaneous leishmaniasis patient with atypical clinical symptoms without splenomegaly but with cutaneous manifestations after treatment of rheumatoid arthritis with methotrexate and blood recovery of the parasite. Next-generation sequencing was used to identify Leishmania infantum chagasi in the patient's blood sample.