VILMA LEYTON
Projetos de Pesquisa
Unidades Organizacionais
Departamento de MedicinaLegal, Ética Médica e Medicina Social e do Trabalho, Faculdade de Medicina - Docente
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense, Hospital das Clínicas, Faculdade de Medicina - Líder
LIM/40 - Laboratório de Imunohematologia e Hematologia Forense, Hospital das Clínicas, Faculdade de Medicina - Líder
6 resultados
Resultados de Busca
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- Alcohol use alone and in combination with other drugs among truck drivers on highways in Sao Paulo State, Brazil: a cross-sectional study(2015) LEOPOLDO, Kae; LEYTON, Vilma; OLIVEIRA, Lucio Garcia deTraffic accidents cause more than a million deaths per year worldwide. Brazil is one of the leading countries in traffic accidents. Since alcohol is a known etiological factor for traffic accidents, the pattern of alcohol use alone and in combination with other drugs was assessed in a convenience sample of 684 truck drivers in Sao Paulo State, Brazil. 67.3% of participants reported alcohol use in the previous 30 days, 34.6% reported heavy drinking, 26% binge drinking, and 9.2% were at risk of developing alcohol addiction. Furthermore, 54.6% reported multiple drug use, mostly alcohol with tobacco and energy drinks. Truck drivers that reported multiple drug use showed heavier alcohol use than those who consumed only alcohol. Drinking and driving is problematic and can be aggravated by multiple drug use. The authors thus suggest monitoring the issue, which creates serious problems for users and society as a whole.
- HAIR DRUG TESTING IN THE NEW BRAZILIAN REGULATION TO OBTAIN PROFESSIONAL DRIVER'S LICENCE: NO PARALLEL TO ANY OTHER LAWENFORCEMENT IN THE WORLD(2015) LEYTON, Vilma; ANDREUCCETTI, Gabriel; ALMEIDA, Rafael Menck de; MUNOZ, Daniel Romero; WALLS, H. Chip; GREVE, Juliamaria D'Andrea; MONTAL, Jose Heverardo da Costa; ADURA, Flavio Emir; YONAMINE, Mauricio
- Association Between Travel Length and Drug Use Among Brazilian Truck Drivers(2015) SINAGAWA, Daniele Mayumi; CARVALHO, Heraclito Barbosa De; ANDREUCCETTI, Gabriel; PRADO, Natanael Vitoriano Do; OLIVEIRA, Keziah Cristina Barbosa Gruber De; YONAMINE, Mauricio; MUNOZ, Daniel Romero; GJERDE, Hallvard; LEYTON, VilmaObjective: To investigate whether the use of the stimulants amphetamines and cocaine by truck drivers in Brazil was related to travel length. Methods: Truck drivers were randomly stopped by the Federal Highway Police on interstate roads in Sao Paulo State during morning hours from 2008 to 2011 and invited to participate in the project ""Comandos de Saude nas Rodovias"" (Health Commands on the Roads). Participants were asked about the use of drugs, travel distance, and age, and gender was recorded. Samples of urine were collected and analyzed for amphetamine, benzoylecgonine (a metabolite of cocaine), and carboxytetrahydrocannabinol (THC-COOH; a metabolite of cannabis) by immunological screening and quantification by gas chromatography-mass spectroscopy. Results: Current use of amphetamine, cocaine, and cannabis was reported by 5.7%, 0.7%, and 0.3% of the truck drivers, respectively. Amphetamine, benzoylecgonine, and THC-COOH were found in urine samples from 5.4%, 2.6,% and in 1.0% of the drivers, respectively. There was a significant association between the positive cases for amphetamine and reported travel length; 9.9% of urine samples from drivers who reported travel length of more than 270km were positive for amphetamine, and 10.9% of those drivers reported current use of amphetamines. In most cases, appetite suppressants containing amphetamines had been used, but the purpose was most often to stay awake and alert while driving. Truck drivers with travel length of more than 270km had significantly higher odds ratio (OR) for having a urine sample that was positive for amphetamine when adjusted for age as confounding factor (OR = 9.41, 95% confidence interval [CI], 3.97-22.26). No significant association was found between the use of cocaine or cannabis and travel length. Conclusion: Truck drivers who reported driving more than 270km had significantly higher frequencies of urine samples positive for amphetamine and reported significantly more frequent current use of amphetamines than those who reported shorter driving distances.
- Occupational conditions and the risk of the use of amphetamines by truck drivers(2015) OLIVEIRA, Lucio Garcia de; SOUZA, Leticia Maria de Araujo de; BARROSO, Lucia Pereira; GOUVEA, Marcela Julio Cesar; ALMEIDA, Carlos Vinicius Dias de; MUNOZI, Daniel Romero; LEYTON, VilmaOBJECTIVE: To test whether the occupational conditions of professional truck drivers are associated with amphetamine use after demographic characteristics and ones regarding mental health and drug use are controlled for. METHODS: Cross-sectional study, with a non-probabilistic sample of 684 male truck drivers, which was collected in three highways in Sao Paulo between years 2012 and 2013. Demographic and occupational information was collected, as well as data on drug use and mental health (sleep quality, emotional stress, and psychiatric disorders). A logistic regression model was developed to identify factors associated with amphetamine use. Odds ratio (OR; 95% CI) was defined as the measure for association. The significance level was established as p < 0.05. RESULTS: The studied sample was found to have an average age of 36.7 (SD = 7.8) years, as well as low education (8.6 [SD = 2.3] years); 29.0% of drivers reported having used amphetamines within the twelve months prior to their interviews. After demographic and occupational variables had been controlled for, the factors which indicated amphetamine use among truck drivers were the following: being younger than 38 years (OR = 3.69), having spent less than nine years at school (OR = 1.76), being autonomous (OR = 1.65), working night shifts or irregular schedules (OR = 2.05), working over 12 hours daily (OR = 2.14), and drinking alcohol (OR = 1.74). CONCLUSIONS: Occupational aspects are closely related to amphetamine use among truck drivers, which reinforces the importance of closely following the application of law (Resting Act (""Lei do Descanso""); Law 12,619/2012) which regulates the workload and hours of those professionals. Our results show the need for increased strictness on the trade and prescription of amphetamines in Brazil.
- RETHINKING THE DEBATE ON DRINKING AND DRIVING LAWS IN SAO PAULO: RESPONSE TO THE LETTER BY VOLPE & FANTONI(2015) ANDREUCCETTI, Gabriel; CARVALHO, Heraclito Barbosa de; CHERPITEL, Cheryl J.; YE, Yu; LEYTON, Vilma
- Risk Factors for Cardiovascular Disease, Metabolic Syndrome and Sleepiness in Truck Drivers(2015) MANSUR, Antonio de Padua; ROCHA, Marcos ABS; LEYTON, Vilma; TAKADA, Julio Yashio; AVAKIAN, Solange Desirée; SANTOS, Alexandre J; NOVO, Gisele C; NASCIMENTO, Arledson Lima; MUñOZ, Daniel Romero; ROHLFS, Waldo J CAbstract Background: Truck driver sleepiness is a primary cause of vehicle accidents. Several causes are associated with sleepiness in truck drivers. Obesity and metabolic syndrome (MetS) are associated with sleep disorders and with primary risk factors for cardiovascular diseases (CVD). We analyzed the relationship between these conditions and prevalence of sleepiness in truck drivers. Methods: We analyzed the major risk factors for CVD, anthropometric data and sleep disorders in 2228 male truck drivers from 148 road stops made by the Federal Highway Police from 2006 to 2011. Alcohol consumption, illicit drugs and overtime working hours were also analyzed. Sleepiness was assessed using the Epworth Sleepiness Scale. Results: Mean age was 43.1 ± 10.8 years. From 2006 to 2011, an increase in neck (p = 0.011) and abdominal circumference (p < 0.001), total cholesterol (p < 0.001), triglyceride plasma levels (p = 0.014), and sleepiness was observed (p < 0.001). In addition, a reduction in hypertension (39.6% to 25.9%, p < 0.001), alcohol consumption (32% to 23%, p = 0.033) and overtime hours (52.2% to 42.8%, p < 0.001) was found. Linear regression analysis showed that sleepiness correlated closely with body mass index (β = 0.19, Raj2 = 0.659, p = 0.031), abdominal circumference (β = 0.24, Raj2 = 0.826, p = 0.021), hypertension (β = -0.62, Raj2 = 0.901, p = 0.002), and triglycerides (β = 0.34, Raj2 = 0.936, p = 0.022). Linear multiple regression indicated that hypertension (p = 0.008) and abdominal circumference (p = 0.025) are independent variables for sleepiness. Conclusions: Increased prevalence of sleepiness was associated with major components of the MetS.